Hasmik Manukyan

Experience

• 

  Bacteriological Laboratory, State Center for Epidemiological Control

  Feb 2009 - Dec 2011

  Junior Scientist

  Performed bacteriological testing of clinical specimens and contributed to data analysis for public health studies.

• 

  Ararat Food Production Company

  Jan 2011 - Jan 2012

  QC Chemist

  Performed microbiological and physicochemical QC for beverages; implemented ISO-compliant documentation.Conducted microbial identification and quality assurance for food safety standards.

• 

  Arpimed Pharmaceutical Company

  Jan 2012 - Mar 2015

  Analytical Chemist

  Performed quality control of pharmaceutical products across multiple dosage forms per USP/Eur.Ph standards.Conducted method validation, cleaning validation, and supported regulatory compliance for manufacturing.

• 

  FDA

  Aug 2015 - May 2023

  Developed and validated multiplex qPCR-based assays for identification, titer determination and neutralization of polio vaccines. Applied NGS methods for genetic consistency and mutation profiling of polio, influenza, Zika, and other viruses, applied UMI-based method for reducing mutation detection error rate. Contributed to the development of self-amplifying mRNA vaccines. Conducted environmental surveillance and identified contaminants in vaccines using molecular methods and high throughput sequencing.

  • Research Scientist

    Oct 2018 - May 2023

  • ORISE Research Fellow

    Aug 2015 - Oct 2018
• 

  National Institute of Allergy and Infectious Diseases (NIAID)

  May 2023 - now

  Research And Development Scientist

  Designed and optimized RT-PCR workflows, including template-switch methods, for sequencing antibody genes. Developed and implemented high-throughput sequencing protocols for monoclonal antibodies.Generated engineered B cell lines via CRISPR and lentiviral transduction to evaluate candidate immunogens. Expressed and purified recombinant proteins; developed fluorescent probes and optimized functional B cell assays.