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Mònica Aguilà

Mònica Aguilà

Professional training

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location of Mònica AguilàLeiden, South Holland, Netherlands

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  • Timeline

  • About me

    Associate Director at ProQR Therapeutics NV

  • Education

    • Universitat Autònoma de Barcelona

      1998 - 2003
      B.Sc. Biotechnology

  • Experience

    • Oryzon

      Nov 2003 - Feb 2004
      Professional training

      Professional training in Oryzon Genomics, a functional genomics company. Participation in the development of the rice atlas expression.

    • Biokit

      Apr 2004 - Sept 2004
      Professional training

      Validation of automated ELISA processing system, ensuring the quality and reliability of the results.

    • Biopole (Namur, Belgium)

      Apr 2005 - Nov 2005
      Research assistant

      Professional training offered by the program of European mobility Eurodyssée in Biopole (Belgium). Research of antibacterial activities of lactic enzymes, especially on Helicobacter pylori.

    • Politechnical University of Catalunya

      May 2006 - Dec 2010
      PhD

      Study of the structure-function relationship of rhodopsin, a model for the GPCRs

    • University College London

      Jan 2009 - Jan 2010
      PhD student visitor

      Visit to Prof. Mike Cheetham's lab, Laboratory of Molecular and Cellular Neuroscience, at the Institute of Ophthalmology, London (UCL)

    • UCL, Institute of Ophthalmology, Ocular Biology and Therapeutics Department

      Jan 2011 - Jun 2016
      Research Associate

      Research project: Investigation and manipulation of photoreceptor proteostasis • Study of the mechanisms that enable correct protein folding in photoreceptors and mediate the cellular response to protein misfolding • Investigation of the therapeutic potential of molecular chaperones in different animal models of rhodopsin retinitis pigmentosa • Manipulation of the gene expression in the retina using AAV vectors • Drug screening using in vivo models in collaboration with pharmaceutical companies and other universities. Show less

    • UCL, Institute of Ophthalomology

      Jun 2016 - Sept 2017
      Research Associate

      Research project: In collaboration with ProQR Therapeutics N.V., use of iPSC to understand RNA processing in retinal dystrophies and develop therapies. • Generate CEP290 LCA-patient derived IPSC lines and differentiate them into 3D optic cup organoids. • Investigate CEP290 deep intonic mutation and test antisense oligonucleotides to correct splicing and restore function

    • UCL, Institute of Ophthalmology

      Sept 2017 - Sept 2019
      Senior Research Associate

      Research project: Study the mechanisms of photoreceptor cell death

    • ProQR Therapeutics

      Oct 2019 - now

      • Associate Director Nonclinical Pharmacology

        Jan 2022 - now

      • Senior Scientist

        Oct 2019 - Dec 2021

  • Licenses & Certifications

    • UK Home Office Personal Licence Holder

      Jan 2011