Sara Omar

Sara Omar

Academic Computational Chemistry Researcher

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location of Sara OmarVancouver, British Columbia, Canada

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  • Timeline

  • About me

    Cheminformatician @ Variational AI | Computational Chemist | I use computers to design drugs for treatment of disease.

  • Education

    • University of Manitoba

      2010 - 2013
      Master's degree Chemistry GPA 4.33

      Activities and Societies: Volunteer for “Let’s Talk Science”, an organization focused on education and outreach to support youth development. Thesis title: “Computational Modelling of Ca2+ and Zn2+ Competition in Calbindin D28k, implications for altering Calcium Homeostasis”

    • The German University in Cairo

      2004 - 2009
      Bachelor of Pharmacy and Biotechnology Pharmacy High Honours

      Activities and Societies: - Member of the Children’s program in “Ashanek ya Baladi (AYB)-GUC” - Member of the “Discovery Toolbox” sponsored by the GUC and Siemens to demonstrate simple physics and chemistry principles to school students using experiments - Member of the Big Buddy Society (BBS) at the GUC to help familiarize new students with university life

    • University of Alberta

      2013 - 2018
      Doctor of Philosophy - PhD Oncology and Cancer Biology
  • Experience

    • University of Manitoba

      Sept 2010 - Dec 2012
      Academic Computational Chemistry Researcher

      - Modelled a calcium binding protein called Calbindin D28k.- Analyzed the protein's structure to understand the underlying mechanism of competition between zinc and calcium ions binding to the protein. This competition is known to have implications in Alzheimer's disease.Courses taught:- Chemical Energetics and dynamics: Macroscopic descriptions (CHEM 2290)- Physical Chemistry: Microscopic descriptions of Matter (CHEM 2280)- University I Chemistry: Structure and Modeling in Chemistry (CHEM 1300)- Assistant in Chemistry Resource Center for first year Chemistry students Show less

    • Faculty of Medicine & Dentistry, University of Alberta

      Jan 2013 - Mar 2020

      - Finalized my PhD thesis entitled “From activation to inhibition: p53 and PNKP as targets for cancer therapy”.- Modelled mutant variants of the transcription factor, p53.- Virtually screened databases to find small molecule activators that can restore the wild-type activity to the mutant protein.- As a member of the Alberta DNA Repair Consortium team, we modelled a DNA repair enzyme called polynucleotide kinase phosphatase (PNKP). The aim of this project is to use PNKP inhibitors for combination cancer therapy.- Used pharmacophore-assisted docking to find inhibitors of PNKP.- Published 8 articles in peer-reviewed journals and assisted in grant writing.- Supervised and mentored an MSc student and trained junior graduate students. Show less

      • Postdoctoral Fellow | Computational Chemistry

        Feb 2019 - Mar 2020
      • Academic Computational Chemistry Researcher

        Jan 2013 - Jan 2019
    • SinoVeda Canada Inc.

      Aug 2019 - Mar 2020
      Computational Research Scientist

      - Assisted in the development of the company's proprietary Pharmaceutical Platform Technology (PPT) to help formulate novel botanical pharmaceuticals.- Collaborated on developing the company's platform algorithms using Github.- Developed an algorithm to construct the pain signalling network to identify target genes.- Used python and SQL to develop an herbal database

    • University of Alberta, Faculty of Science

      Apr 2020 - Jan 2021
      Postdoctoral Researcher | Computational Chemistry

      - Creating models of the SARS-CoV2 programmed ribosomal frameshifting element for targeting against COVID-19.- Virtual screening of FDA approved drugs to identify inhibitors of the SARS-CoV2 frameshifting element for experimental validation.- Virtual screening and optimization of novel inhibitors of the SARS-CoV2 frameshifting element.

    • Diagen AI

      Feb 2021 - May 2024
      • Lead Computational Structural Biology Scientist

        Sept 2021 - May 2024
      • Computational Structural Biology Scientist

        Feb 2021 - Aug 2021
    • Variational AI

      May 2024 - now
      Computational Chemist | Cheminformatician
  • Licenses & Certifications

    • Data Analysis Using Python

      University of Pennsylvania
      Mar 2024
      View certificate certificate
    • Open Water Diver

      PADI
      Dec 2019
    • NumPy Essential Training: 1 Foundations of NumPy

      LinkedIn
      Mar 2024
      View certificate certificate
    • Machine Learning Foundations 2

      Alberta Machine Intelligence Institute (Amii)
      Oct 2022
      View certificate certificate
    • 6.00.1x: Introduction to Computer Science and Programming Using Python

      MITx Courses
      Mar 2020
      View certificate certificate
    • Neural Networks and Deep Learning

      Coursera
      Sept 2023
      View certificate certificate
    • Pharmacist

      Egyptian Pharmacists Syndicate - النقابة العامة لصيادلة مصر
      Jan 2019
    • Machine Learning Foundations 1

      Alberta Machine Intelligence Institute (Amii)
      Oct 2022
      View certificate certificate
    • Management Skills Certificate

      Langara College
      Aug 2022
  • Honors & Awards

    • Awarded to Sara Omar
      75th Anniversary Graduate Student Award Faculty of Medicine & Dentistry at the University of Alberta Jan 2017
    • Awarded to Sara Omar
      Category A Scholarship German University in Cairo Sep 2016 50% tuition fees reduction for three years
    • Awarded to Sara Omar
      Department of Oncology Differential fees tuition remission award Department of Oncology, University of Alberta Sep 2016
    • Awarded to Sara Omar
      Department of Oncology Differential fees tuition remission award Department of Oncology, University of Alberta Sep 2014
    • Awarded to Sara Omar
      Antoine Noujaim Scholarship Alberta Cancer Foundation Jan 2013
    • Awarded to Sara Omar
      University of Alberta Entrance Award University of Alberta Jan 2013
    • Awarded to Sara Omar
      Campbell / Charlesworth Graduate Bursary University of Manitoba Dec 2011
    • Awarded to Sara Omar
      Hugh J. Anderson Graduate Award University of Manitoba Dec 2011
    • Awarded to Sara Omar
      Robert H. Betts Graduate Award University of Manitoba Dec 2011
    • Awarded to Sara Omar
      Faculty of Science Graduate Scholarship University of Manitoba Sep 2011
    • Awarded to Sara Omar
      Chemistry Centennial Scholarship University of Manitoba Dec 2010
    • Awarded to Sara Omar
      Ernst and Ingrid Bock Graduate Award University of Manitoba Dec 2010
    • Awarded to Sara Omar
      Hugh J. Anderson Graduate Award University of Manitoba Dec 2010
    • Awarded to Sara Omar
      Faculty of Science Graduate Scholarship University of Manitoba Sep 2010
    • Awarded to Sara Omar
      International Graduate Student Entrance Scholarship University of Manitoba Sep 2010
  • Volunteer Experience

    • Trainee Committee President

      Issued by Cancer Research Institute of Northern Alberta on Jun 2017
      Cancer Research Institute of Northern AlbertaAssociated with Sara Omar
    • Vice President

      Issued by Egyptian Student Association in North America on May 2019
      Egyptian Student Association in North AmericaAssociated with Sara Omar
    • Judge

      Issued by FIRST Lego League on Jan 2018
      FIRST Lego LeagueAssociated with Sara Omar
    • Volunteer

      Issued by Let's talk Science, University of Manitoba on May 2010
      Let's talk Science, University of ManitobaAssociated with Sara Omar