
Sara Omar
Academic Computational Chemistry Researcher

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About me
Cheminformatician @ Variational AI | Computational Chemist | I use computers to design drugs for treatment of disease.
Education

University of Manitoba
2010 - 2013Master's degree Chemistry GPA 4.33Activities and Societies: Volunteer for “Let’s Talk Science”, an organization focused on education and outreach to support youth development. Thesis title: “Computational Modelling of Ca2+ and Zn2+ Competition in Calbindin D28k, implications for altering Calcium Homeostasis”

The German University in Cairo
2004 - 2009Bachelor of Pharmacy and Biotechnology Pharmacy High HonoursActivities and Societies: - Member of the Children’s program in “Ashanek ya Baladi (AYB)-GUC” - Member of the “Discovery Toolbox” sponsored by the GUC and Siemens to demonstrate simple physics and chemistry principles to school students using experiments - Member of the Big Buddy Society (BBS) at the GUC to help familiarize new students with university life

University of Alberta
2013 - 2018Doctor of Philosophy - PhD Oncology and Cancer Biology
Experience

University of Manitoba
Sept 2010 - Dec 2012Academic Computational Chemistry Researcher- Modelled a calcium binding protein called Calbindin D28k.- Analyzed the protein's structure to understand the underlying mechanism of competition between zinc and calcium ions binding to the protein. This competition is known to have implications in Alzheimer's disease.Courses taught:- Chemical Energetics and dynamics: Macroscopic descriptions (CHEM 2290)- Physical Chemistry: Microscopic descriptions of Matter (CHEM 2280)- University I Chemistry: Structure and Modeling in Chemistry (CHEM 1300)- Assistant in Chemistry Resource Center for first year Chemistry students Show less

Faculty of Medicine & Dentistry, University of Alberta
Jan 2013 - Mar 2020- Finalized my PhD thesis entitled “From activation to inhibition: p53 and PNKP as targets for cancer therapy”.- Modelled mutant variants of the transcription factor, p53.- Virtually screened databases to find small molecule activators that can restore the wild-type activity to the mutant protein.- As a member of the Alberta DNA Repair Consortium team, we modelled a DNA repair enzyme called polynucleotide kinase phosphatase (PNKP). The aim of this project is to use PNKP inhibitors for combination cancer therapy.- Used pharmacophore-assisted docking to find inhibitors of PNKP.- Published 8 articles in peer-reviewed journals and assisted in grant writing.- Supervised and mentored an MSc student and trained junior graduate students. Show less
Postdoctoral Fellow | Computational Chemistry
Feb 2019 - Mar 2020Academic Computational Chemistry Researcher
Jan 2013 - Jan 2019

SinoVeda Canada Inc.
Aug 2019 - Mar 2020Computational Research Scientist- Assisted in the development of the company's proprietary Pharmaceutical Platform Technology (PPT) to help formulate novel botanical pharmaceuticals.- Collaborated on developing the company's platform algorithms using Github.- Developed an algorithm to construct the pain signalling network to identify target genes.- Used python and SQL to develop an herbal database

University of Alberta, Faculty of Science
Apr 2020 - Jan 2021Postdoctoral Researcher | Computational Chemistry- Creating models of the SARS-CoV2 programmed ribosomal frameshifting element for targeting against COVID-19.- Virtual screening of FDA approved drugs to identify inhibitors of the SARS-CoV2 frameshifting element for experimental validation.- Virtual screening and optimization of novel inhibitors of the SARS-CoV2 frameshifting element.

Diagen AI
Feb 2021 - May 2024Lead Computational Structural Biology Scientist
Sept 2021 - May 2024Computational Structural Biology Scientist
Feb 2021 - Aug 2021

Variational AI
May 2024 - nowComputational Chemist | Cheminformatician
Licenses & Certifications
- View certificate

Data Analysis Using Python
University of PennsylvaniaMar 2024 
Open Water Diver
PADIDec 2019- View certificate

NumPy Essential Training: 1 Foundations of NumPy
LinkedInMar 2024 - View certificate
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Machine Learning Foundations 2
Alberta Machine Intelligence Institute (Amii)Oct 2022 - View certificate

6.00.1x: Introduction to Computer Science and Programming Using Python
MITx CoursesMar 2020 - View certificate

Neural Networks and Deep Learning
CourseraSept 2023 
Pharmacist
Egyptian Pharmacists Syndicate - النقابة العامة لصيادلة مصرJan 2019- View certificate
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Machine Learning Foundations 1
Alberta Machine Intelligence Institute (Amii)Oct 2022 
Management Skills Certificate
Langara CollegeAug 2022
Honors & Awards
- Awarded to Sara Omar75th Anniversary Graduate Student Award Faculty of Medicine & Dentistry at the University of Alberta Jan 2017
- Awarded to Sara OmarCategory A Scholarship German University in Cairo Sep 2016 50% tuition fees reduction for three years
- Awarded to Sara OmarDepartment of Oncology Differential fees tuition remission award Department of Oncology, University of Alberta Sep 2016
- Awarded to Sara OmarDepartment of Oncology Differential fees tuition remission award Department of Oncology, University of Alberta Sep 2014
- Awarded to Sara OmarAntoine Noujaim Scholarship Alberta Cancer Foundation Jan 2013
- Awarded to Sara OmarUniversity of Alberta Entrance Award University of Alberta Jan 2013
- Awarded to Sara OmarCampbell / Charlesworth Graduate Bursary University of Manitoba Dec 2011
- Awarded to Sara OmarHugh J. Anderson Graduate Award University of Manitoba Dec 2011
- Awarded to Sara OmarRobert H. Betts Graduate Award University of Manitoba Dec 2011
- Awarded to Sara OmarFaculty of Science Graduate Scholarship University of Manitoba Sep 2011
- Awarded to Sara OmarChemistry Centennial Scholarship University of Manitoba Dec 2010
- Awarded to Sara OmarErnst and Ingrid Bock Graduate Award University of Manitoba Dec 2010
- Awarded to Sara OmarHugh J. Anderson Graduate Award University of Manitoba Dec 2010
- Awarded to Sara OmarFaculty of Science Graduate Scholarship University of Manitoba Sep 2010
- Awarded to Sara OmarInternational Graduate Student Entrance Scholarship University of Manitoba Sep 2010
Volunteer Experience
Trainee Committee President
Issued by Cancer Research Institute of Northern Alberta on Jun 2017
Associated with Sara OmarVice President
Issued by Egyptian Student Association in North America on May 2019
Associated with Sara OmarJudge
Issued by FIRST Lego League on Jan 2018
Associated with Sara OmarVolunteer
Issued by Let's talk Science, University of Manitoba on May 2010
Associated with Sara Omar
Languages
- enEnglish
- arArabic
- frFrench
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