Susan Elliott

Experience

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  Zeneca

  Sept 1995 - Jul 1998

  Research Associate I

  Sept 1995-July 1998 Associate Chemist, Astra-Zeneca. Supervisor/study director Majid Akhavan (contact info Pacific Analytical Laboratories, Alameda CA, Tel: (510) 864-0364)•Conducted Soil and animal studies to ID metabolites under GLP, for EPA•Developed extraction methods, liq-liq, liq-solid, homogenization, centrifugation, acid hydrolysis, closed vessel microwave extraction to isolate and purify pesticide metabolites.•Developed HPLC and TLC methods, c14 radio label detection Prepared written research reports, SOPs Show less

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  AgraQuest, Inc.

  Jan 1998 - Jan 2002

  Research associate III

  August 1998- March 2002 Associate Researcher, Dept of Natural Products Chemistry, Agraquest Inc., 1530 Drew Ave, Davis CA 95616. 530-750-0150. Supervisor Denise Manker. •Develop and qualify new extraction methods and characterization methods to purify natural products from fermentation broth, liquid-liquid extraction, flash column chromatography, RP, SEC, IEX UV/Vis SPE. Identify by LCMS. Wrote research reports, test methods, and research proposals.•Transfer methods and audit contract manufactures. •Critical member of a team that set up new testing lab in Tlaxcala, Mexico. Purchase, ship and install equipment. Train, and audit personnel •Trouble shoot maintain and repair Agilent HPLC’s in laboratory. •Screen new microbes against known toxins using HPLC uv/vis data base Show less

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  ZymoGenetics

  Mar 2002 - May 2006

  Research Associate III

  March 2002 – May 2006, Research Associate III, ZymoGenetics, Bioanalytical and Formulations group 1201 Eastlake Ave E, Seattle, WA, 98102. Supervisor Sibylle Wilbert, Senior scientist II (sybille.wilbert@gilead.com, )•Develop, qualify and transfer stability-indicating assays for recombinant protein drug products and drug intermediates. Assays: peptide maps, SEC, CEX, RP-HPLC, UV/VIS and light scattering detection. Also used these method to analyzed dug product for shipping stability and formulation studies.•Write detailed research reports, test method, SOPs, and training documents.•Lead for trouble-shooting, repairing and maintaining Agilent HPLCs. Wrote SOP for maintenance and repair of HPLCs, and training protocols. Show less

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  Amgen

  May 2006 - Apr 2010

  Associate Scientist

  Analytical Sciences, Amgen Inc, Supervisor Wesly Wang and Jiu-Li Song.•Develop, qualify and transfer stability-indicating HPLC assays (SEC, CEX, RP) with UV/VIS detection for monoclonal antibodies. Documenting method development in written research reports and orally presentations.•Characterize monoclonal antibodies via (SEC, RP, CEX)-HPLC, rCE-SDS glycan analysis, peptide maps with LC-MS detection for full sequence coverage, and disulfide bond bridges•Conduct assays HPLC, rCE, CIEF, TOC, HIAC, protein concentration for stability and relase under GLP regulations. Show less

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  University of Washington

  May 2010 - Feb 2020

  Research Scientist III

  • Project lead for several clinical pilot studies for Lysosomal Storage Disease. • Implement and evaluate the use of tandem mass spectrometry (LC/MS/MS) as a high-throughput screening assay for the detection of lysosomal storage disorders in newborns.• Manage daily operations, daily clinical testing, manage resources and supply chain. Investigate and implement process improvements.• Train and supervise laboratory personnel• Write SOP’s and protocols and publications, perform safety assessments. Assist in performance reviews. • Extract and process neonatal samples and QC samples, to generate mass data. Perform statistical analysis, histograms, regression analysis, Anova, intra and inter assay variability. Determine disease cutoffs, trends in sample age, type and matrix, reagent lot variability, key performance criteria. • Maintain, diagnose and repair scientific instrumentation, pumps, autosampler, Waters Inc HPLC and TQD mass spectrometer, auto pipettors, HPLCs, SPE driers, nitrogen generators. • Assist in development and implementation of new screening methods• Collaborate and train international scientists, on LC-MS-MS assays in additional laboratories. • Presented UW research at several scientific conferences Show less

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  Graduate Student , in Data Science Program at Eastern University

  Aug 2023 - now

  Graduate Student , in Data Science Program at Eastern University