Jean-Michel Carter

Experience

• 

  NERC

  Sept 2008 - Jul 2009

  Sandwich Course Student

  NERC Internship at the Centre for Ecology and Hydrology (CEH) assisting Prof. Robert D. Possee with baculovirus research.• Classified hyper variable DNA regions and discovered a novel transposon: Generated and analysed baculovirus sequencing data in a Linux environment.• Identified new conditions for induction of cytopathic effects: Performed experiments recombineering baculoviruses and transfecting insect cell lines.

• 

  University of Oxford

  Jun 2014 - Aug 2014

  Postdoctoral Researcher

  Research (Ferguson Lab. & Breuker Lab.) - Pilot postdoctoral project with Dr Laura Ferguson.• Characterised the molecular expression of a large gene family: Performed experiments and bioinformatics (WMISH, sequence analyses) with pilot funding and supervision from Dr Laura Ferguson.

• 

  University of Oxford

  Nov 2014 - Jun 2015

  Postdoctoral Researcher

  Research (Aboobaker Lab.) - Investigating stem cells, regeneration and ageing using Planarian flatworms• Identified telomerase isoforms by integrating NGS and RACE data: Designed and performed experiments (RACE) and sequence analyses (bash).• Characterised the role of JNK signaling in posterior regeneration of a flatworm (S. med): Performed revision experiments (RNAi, drug treatment, FISH) and co-authored paper.• Established a 3-year fellowship proposal to investigate RNA methylation in S. med: Designed, performed pilot experiments (RNAi, sequence analyses) and authored proposal.Teaching, Public Engagement and other Activities:- Oxford Stem Cell Institute Annual Symposium Delegate (2015)- International Symposium of Flatworm Biology Delegate (2015)- Big Data Science in Medicine 2014 (2014 Sep. & Dec. Symposiums) Delegate Show less

• 

  University of Bath

  Apr 2016 - Aug 2019

  Research Associate

  Research (Hussain Lab.) - Investigating RNA modifications using sequencing techniques and bioinformatics:• First study profiling m5U RNA modifications at single nucleotide resolution across the human transcriptome, using novel NGS-based CLIP techniques: Performed experiments, analyses (bash/R) and co-authored manuscript. Initial data processed in collaboration with the Francis Crick Institute (Üle).• First study benchmarking direct human genome sequencing with Oxford Nanopore Tech. (ONT) MinION: Performed all analyses independently (bash, various tools and R) and co-authored manuscript.• Created pipelines to detect m6A RNA modifications in MinION data from novel CLIP-based experiments: Tested and troubleshooted different pipeline configurations and tools (bash/Python).• Benchmarking m5C identification from direct RNA sequencing using MinION: Performing all analyses independently using tombo, Python, bash and R (in preparation)• Supervised BSc, MSc experimental and bioinformatic student projects: Mostly teaching bioinformatics but also genotyping and characterising Zebrafish mutants.Teaching, Public Engagement & Other Activities:- Delivered lectures on Sequencing Technologies & Bioinformatics to the Intellectual Property Office (10/05/2017).- Delivered lecture on applying for postgraduate education to prospective international students (18/07/2017).- Founded the Postdoctoral Society for the Dept. of Biology & Biochemistry in October 2018. Chairing the organising committee.- Active Committee Member of Bath Science in Policy since September 2017. Helped organise 10+ events including chairing a panel discussion on AI & Policy (13/11/2018), attending an APPG on Chemical Weapons (19/01/2018) and networking with policy stakeholders.- Supervised 5 Undergraduate Project Students & 2 MRes Project Students- Entered the Royal Society "The Pitch" Competition for Research Culture: Changing Expectations Conference. Show less

• 

  Nanyang Technological University

  Apr 2020 - now

  Research Fellow