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Maria Casquinha

Maria Casquinha

Contribution for a doctoral thesis in Pharmaceutical Sciences

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  • Timeline

  • About me

    PhD Student (Body Barrier Immunometabolism Group, CNC-UC)

  • Education

    • Faculty of Science and Technology of the University of Coimbra

      2023 - 2027
      Doctor of Philosophy - PhD

    • Faculty of Sciences and Technology of the University of Coimbra

      2020 - 2022
      Master's in Cellular and Molecular Biology Neurobiology 18/20

      Master Thesis: "The impact of postnatal allergies in microglia-mediated cerebellar maturation"Establishment and validation of a postnatal experimental allergy model in order to study allergen (House Dust Mites)-evoked alterations in cerebellar microglia and its circuit, as well as to probe the animals for ADHD-related hyperactive traits.- Use of several cellular and molecular techniques such as flow cytometry, qRT-PCR and ELISA- Retrieval and processing of brain slices to… Show more Master Thesis: "The impact of postnatal allergies in microglia-mediated cerebellar maturation"Establishment and validation of a postnatal experimental allergy model in order to study allergen (House Dust Mites)-evoked alterations in cerebellar microglia and its circuit, as well as to probe the animals for ADHD-related hyperactive traits.- Use of several cellular and molecular techniques such as flow cytometry, qRT-PCR and ELISA- Retrieval and processing of brain slices to count cerebellar microglia and perform Sholl and surface analysis after 3D reconstruction, following IBA-1 immunohistochemistry and confocal microscopy- Electrophysiological recordings of AMPA-mediated miniature excitatory postsynaptic currents- Behavioral paradigms: open field, running wheels and delay aversion T-Maze (Accompanied all procedures, while supervised by a senior member of the laboratory) Show less

    • Faculty of Pharmacy of the University of Coimbra

      2017 - 2020
      Bachelor's degree in Biomedical Pharmacy 15/20

      Relevant educational training:- Introductory subjects in the areas of Biochemistry, Cell and Molecular Biology, Chemistry, Anatomy, Maths, Statistics and English- Specialized subjects in Pharmacology, Clinical Trials, Regulatory Affairs, Pharmacovigilance and Pharmacoepidemiology

    • Basic and Secondary School of Cadaval

      2009 - 2017
      Science and Technology 16/20

      Activities and Societies: Clube + (Young VolunTeam Program, promoted by Caixa Geral de Depósitos, in school year 2014/2015) ; Academic sports team

  • Experience

    • Faculty of Pharmacy of the University of Coimbra

      May 2019 - May 2019
      Contribution for a doctoral thesis in Pharmaceutical Sciences

      Sporadic colaboration in the experimental work in accumulation assays to assess the inhibitory effect of antiepileptic drugs over BCRP developed for a doctoral thesis in Pharmaceutical Sciences under the supervision of Professor Ana Fortuna, PhD.

    • CNC UC

      Apr 2021 - Sept 2022

      Master Thesis Student

      • Member of Neuronal Circuits and Behavior Lab at CNC

        Jan 2021 - Sept 2022

      • Laboratory Rotation at Neurotrophin signaling and synaptic (dys)function laboratory

        Apr 2021 - May 2021

    • Center for Neuroscience and Cell Biology

      Nov 2022 - Jun 2023
      Research Fellowship - MJDEdit

      Research fellowship to work on the MJDEdit project at Vectors and Gene Therapy group (CNC) to validate CRISPR-Cas9 sequences in both cellular and animal models, aiming to mitigate disease features and symptoms.

    • Center for Neuroscience and Cell Biology

      Oct 2023 - now
      PHD Student

  • Licenses & Certifications

    • V Symposium of the Portuguese Glial Network

      Portuguese Glial Network
      Nov 2021

    • Member of Portuguese Glial Network

      Portuguese Glial Network
      Jan 2021
      View certificate certificate

    • III Week of Biomedical Pharmacy

      Comissão de Curso da Licenciatura em Farmácia Biomédica
      May 2020

    • I Semana de Farmácia Biomédica

      Comissão de Curso da Licenciatura em Farmácia Biomédica
      Apr 2018

    • IV Jornadas das Saídas Profissionais

      Coordenação do Pelouro dos Estágios e Saídas Profissionais do Núcleo de Estudantes de Farmácia da Associação Académica de Coimbra
      Oct 2017

    • DruSER.Net – Drug Safety and Effectiveness Research Network 1st Meeting

      AIBILI-Association for Innovation and Biomedical Research on Light and Image
      Dec 2019

    • Biomedicines | Recent Advances in Mitochondrial Biology

      MDPI
      Oct 2022

    • 1st Drugs R&D PhD Symposium – Translational Science: From Academia to Industry

      Faculdade de Farmácia da Universidade de Coimbra
      Sept 2018

    • XI Congresso Científico NEF/AAC – Terapias Biológicas – Na vanguarda da saúde

      Núcleo de Estudantes de Farmácia da Associação Académica de Coimbra (NEF/AAC)
      Nov 2017

    • Brain Gain

      CNC UC
      Mar 2021

  • Honors & Awards

    • Awarded to Maria Casquinha
      Best student in the Bachelor's degree of Biomedical Pharmacy, Class of 2020 Faculty of Pharmacy of the University of Coimbra Apr 2022
    • Awarded to Maria Casquinha
      Municipality School Merit Award, Class of 2017 City council of Cadaval Sep 2017
    • Awarded to Maria Casquinha
      Text reading contest «Dá voz à letra» Fundação Calouste Gulbenkian 2015 Good communication skills acquired through the participation in the three phases (up to the final) of a textreading contest for the secondary school students of the Lisbon Region organized by the Department of Portuguese Language and Culture of Fundação Calouste Gulbenkian.

  • Volunteer Experience

    • Member of Serviço Pastoral do Ensino Superior (SPES) Coimbra

      Issued by Instituto Universitário Justiça e Paz/Casa de Saúde do Telhal on Apr 2018
      Instituto Universitário Justiça e Paz/Casa de Saúde do TelhalAssociated with Maria Casquinha