Gabriel Goodney

Experience

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  Maryland Police and Correctional Training Commission

  Jul 2014 - Aug 2014

  IT Intern

  • Managed and replaced servers• Added wireless access points to a larger network• Coded MySQL

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  Washington & Jefferson College

  Sept 2014 - Jan 2015

  • Research assistant to Dr. Damian Carrieri of Matrix Genetics and Dr. Thomas Lombardi of Washington & Jefferson College. Literature research and data analysis of gene and protein transcripts for wild-type and nitrogen-starved cyanobacteria.• Compared significant changes in up-regulation and down-regulation of gene expression to protein expression of wild type and mutant cyanobacteria to understand the responses of nitrogen-starvation • Assisted students in understanding laboratory safety and techniques• Setup and prepared materials before class

  • Research Assistant

    Dec 2013 - Jan 2015

  • Biology 101 Lab Assistant

    Sept 2014 - Dec 2014
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  San Diego State University-California State University

  Jan 2016 - May 2017

  • Instructed Biology 203L: Principles of Cell and Molecular Biology• Facilitated interactions with students to achieve lecture outcomes • Used SYBR Gold staining and epifluorescent microscopy to count bacteria and virus-like particles• Performed non-parametric tests to determine if relationships exist between time, materials, condition, and organismal growth• Used 16S and ITS sequence data to create microbial co-occurrence networks using SparCC

  • Teaching Associate

    Jan 2017 - May 2017

  • Graduate Researcher

    Jan 2016 - May 2017
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  National Human Genome Research Institute (NHGRI)

  May 2018 - Sept 2024

  Currently, I work within the Metabolic, Cardiovascular and Inflammatory Disease GenomicsBranch of NHGRI, as part of Dr. Gary Gibbons’ laboratory. As a group, we investigate how social and environmental factors influence cardiovascular disease in African Americans by taking an 'Omics' approach to begin to unravel this complex disease. My current role requires Python, R and Bash scripting in linux, HPC, and cloud environments to handle and process large, multi-omic human NGS datasets. On a daily basis, I process mRNA sequencing, methylation sequencing, whole genome sequencing and other omic data from raw reads to analysis-ready files. I look forward to continuing to learn, grow, sharpen my programming skills, and strengthen my statistical skills so that I can make informed, robust inferences on the relationship between genomics, environmental factors and phenotypic traits. Show less • Provide lab members with recommendations on optimal quality controls to apply to raw data and support in implementing those techniques• Apply computational theoretical principles to understand biological systems and carry out biological methods and procedures• Advise the lab on experimental design, development and analysis of microbiome data• Development of Genetic Local Ancestry computational pipeline for Gibbons Group genetic data• Development of Bisulfite Methylation computational pipeline for Gibbons Group methylation sequencing data • Implementation of the Broad Institute’s pipeline for RNA-seq data in the Gryphon cluster space dedicated to Gibbons Group• Analyze and interpret output data from the computational pipelines and provides summaries to the group• Preparation and imputation of Gibbons Group genotype data using Michigan’s Imputation Server• Quality assessment and maintenance of phenotype data collected for the GENE-FORECAST study• Management and maintenance of data generated or acquired by Gibbons Group (MH-GRID, GENE-FORECAST, UK-Biobank)• Pilot and test the DNAnexus cloud-computing platform• Maintenance of Gibbons group genome and transcriptome computational pipelines on the Gryphon High Performance Computing cluster Show less

  • Bioinformatician

    Jul 2020 - Sept 2024

  • Data Analyst

    Jan 2019 - Jul 2020

  • Postbac Fellow IRTA

    May 2018 - Jan 2019
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  National Heart, Lung, and Blood Institute

  Mar 2024 - now

  Staff Bioinformatician