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Nisha Sipes

Nisha Sipes

Mechanical Engineer

Followers of Nisha Sipes931 followers
location of Nisha SipesDurham, North Carolina, United States

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  • Timeline

  • About me

    Assistant Center Director for Research Translations and Program/Regulatory Support at US Environmental Protection Agency (EPA)

  • Education

    • University of Cincinnati, College of Medicine

      2004 - 2009
      PhD Cancer and Cell Biology

      • Rho GTPases in extracellular matrix remodeling in three dimensions• Rationalized drug design• Max Planck Institute of Molecular Cell Biology and Genetics- Atomic Force Microscope evaluation• 4 Awards and Fellowships

    • University of Cincinnati, College of Engineering, College of Medicine

      2002 - 2004
      MS Biomedical Engineering

      • Gait kinematics device accuracy and reliability testing for use in tendon/ligament repair• 4 Awards and Fellowships

    • University of Cincinnati, College of Engineering

      1997 - 2002
      BS Mechanical Engineering

      • 4 Awards and Scholarships

  • Experience

    • Cincinnati Machine

      Sept 1998 - Dec 1999
      Mechanical Engineer

      • Conducted and analyzed vibration and noise related experiments on milling machines• Designed and published departmental work instructions to standardize operating procedures

    • Ethicon Endo-Surgery

      Mar 2000 - Sept 2001
      Mechanical Engineer

      • Medical device concept, protocol, prototype, evaluation, and patent claim development• Products included breast biopsy device, tissue marker, radiation detecting device, and tissue cutter/cauterizer• Extensive intellectual property review lead• Market research with key clinicians• Contractor liaison

    • University of Cincinnati

      Jun 2002 - Sept 2002
      Biomedical Engineer (Environmental Health)

      • Manuscript research and method development using non-invasive techniques• Environmental toxicological studies focused on biomechanics and ergoniomics

    • US Environmental Protection Agency (EPA)

      Sept 2009 - Oct 2014

      Researching novel approaches for integrating high-throughput screening data to advance risk assessment • Systems biology approach to understand potential pathways involved in developmental toxicology• Computational predictive model development using high throughput and high content screening data (>600 assays) and prenatal guideline data (two species)• Zebrafish embryo assay concordance evaluation with developmental toxicity• Evaluation of 2000 chemicals in 300 biochemical assays• 11 awards and honors

      • ORISE Fellow at US EPA, National Center for Computational Toxicology

        Sept 2013 - Oct 2014

      • Computational Biologist, National Center for Computational Toxicology

        Sept 2009 - Sept 2013

    • National Institute of Environmental Health Sciences (NIEHS)

      Oct 2014 - Nov 2020
      Health Science Evaluator

      • within the National Toxicology Program • Tox21 and ToxCast data • Researching chemical high-throughput and high-content screening data in the context of biological pathways and in vivo phenotypes to better understand chemical-biology interactions.

    • US Environmental Protection Agency (EPA)

      Nov 2020 - now
      Assistant Center Director

  • Licenses & Certifications

    • Engineer In Training (EIT)

      May 2002