Chang Sue-Ming

Experience

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  中央研究院

  Aug 2014 - Aug 2017

  Postdoctoral Fellow

  In vivo and vitro biological experience• Experience in Target Drug Delivery systems: Preparation of target Liposomal agent (anticancer drug)• Experience in elevation of the anti-cancer agent in vitro and vivo experience: Cell Culture, Cytotoxicity assay, Weston blot, Protein purification, In vivo animal model (nude mice)Chemical and enzymatic synthesis• Experience in design and synthesis of the target anti-cancer agent (New Drug): Topoisomerase inhibitor, DNA alkylating agent, Kinase inhibitor• Experience in synthesis of the orthogonal protected- monosaccharides (galactose, glucosamine, mannose) and assemble the versatile monosaccharides to carry out the polysaccharides.• Experience in chemoenzymatic synthesis of saccharides by fucosyltransferase and L-Fucokinase/L-fucose-1-P guanylyltransferase (FKP) for the saccharides fucosylation.Natural product identification and analysis• Experience in isolation and purification of the natural products by silica gel column chromatography, HPLC, recycle HPLC and GC-MS and qualitative and quantitative analysis by HPLC and GC-MS.• Expertise in various spectroscopic (1D & 2D NMR) and chromatographic techniques.• Expertise in analyzing 1D NMR (1H NMR, 13C NMR), 2D NMR (COSY, NOESY, DEPT, HMBC, HSQC), Mass, IR and UV spectral data for structural determination of natural products and small molecules. 收回

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  Academia Sinica, Department of Intellectual Property and Technology Transfer

  Jan 2017 - Jan 2020

  Technology Transfer Manager
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  Anbogen Therapeutics, Inc

  Jan 2021 - now

  Director Of Intellectual Property and Research Development