Débora Moreira

Experience

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  ICBAS/UP - Institute for the Biomedical Sciences Abel Salazar / Porto University

  Jan 2012 - Sept 2016

  Scientific research collaborator

  Collaborator/researcher in the project “Effects of low-frequency sound irradiation in tissues”, held byFaculty of Engineering and ICBAS (Instituto de Ciências Biomédicas Abel Salazar) both of University ofPorto. In this project I prepared tissue samples (Sirius Red histological staining) from rodents after noise exposure, with or without stress inhibitors. The samples were analysed through optical microscopy. The differences between groups where quantified by image quantification using Image J software. In this project, I have developed image analysis and quantification skills.Developed lab techniques:- Histological staining- Optical microscopy- Image analisys- Image quantification Show less

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  Faculty of Engineering, University of Porto

  Jul 2014 - Aug 2014

  Monitor of Junior University

  Management and planning of a laboratory activity in the bioengineering area for 10 and 11º grade students.

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  Interdisziplinären Zentrums für Neurowissenschaften (IZN)

  Feb 2016 - Jul 2016

  ERASMUS Research training - Research trainee in Neuroscience Research Group

  ERASMUS internship at Heidelberg University (Germany) in the IZN (Interdisciplinary center for neurosciences) group. In this training, I wished to assess how the biogenic amine octopamine exerts its strong modulation effect on the endogenous motor pattern in D. melanogaster. In this project I have done larval fillet preparations for electrophysiological recordings and functional imaging, in vivo intracellular current clamp recordings of muscle membrane potentials, in vivo calcium imaging in defined octopaminergic neurons with simultaneous membrane potential recordings and genetic manipulation of Drosophila larvae.Developed lab techniques:- D. melanogaster maintenance- Larval fillet preparations- in vivo intracellular current clamp recordings of muscle membrane potentials- in vivo imagingFinal grade of research training: 20/20 Show less

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  I3S - Instituto de Investigação e Inovação em Saúde

  Feb 2017 - Jan 2018

  Master Thesis Student

  Master thesis in “Nanobiomaterials For Targeted Therapies” research group. I have worked with the goal to develop and implement an innovative dynamic in vitro model of the blood-brain barrier in stroke. The final aim of the model was to quantify the crossing of nanoparticles (dendrimers) through the barrier and determine the possible toxicity they could cause on the cells. As a control, a static model of blood-brain barrier was also implemented using Transwell“. The results of the thesis were published in the Journal of Controlled Release.Developed lab techiniques:- Cell culture (cell line and primary cells)- Immunocytochemistry- Confocal imaging- Spectrophotometry- Transendothelial Electrical Resistance (TEER)Final Grade: 19/20 Show less

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  Glintt

  Jan 2018 - Apr 2020

  As a quality assurance analyst, I am responsible for detecting and ensuring the correction of bugs on the developed Software. To this end, I design, execute and document scenarios and test cases, using tools such as Hewlett Packard Enterprise (HPE), Xray, JIRA and Confluence. Since I have started, I detected over 800 bugs and created more than 1800 case tests, which improved the product stability and quality. With this position I have honed skills as accuracy, critical thinking, attention to detail, organization and documentation. Show less

  • Quality Assurance Analyst

    Sept 2018 - Apr 2020

  • Junior Consultant

    Jan 2018 - Aug 2018
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  I3S - Instituto de Investigação e Inovação em Saúde

  Sept 2020 - now

  Researcher - PhD student

  PhD research project on the topic of Biotechnology and Biomedical engineering.The main objective of the project is to develop a multifunctional dendrimer-based strategy as a disease-modifying therapy for Alzheimer's disease. The project is held at i3S institute in “Nanobiomaterials For Targeted Therapies” research group (supervision of Prof.ª Dr. Ana Paula Pêgo).