Kate Rantanen

Education

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  University of Toronto

  1998 - 2003

  Hons. B. Sc. Chemistry

  My undergraduate research project was carried out in the laboratory of Dr. Andrei K. Yudin.

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  Dalhousie University

  2003 - 2005

  M.Sc. Bio-inorganic Chemistry

  Attività e associazioni:Dalhousie Graduate Chemistry Society A systematic investigation of interactions between biologically relevant peptides and heavy metals was performed using electrospray ionization mass spectrometry (ESI-MS) as an analytical tool, in the laboratory of Dr. Neil Burford.

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  Queen's University

  2005 - 2012

  Doctor of Philosophy (Ph.D.) Synthetic Organic Chemistry & Mechanistic Enzymology

  Attività e associazioni:Queen's Mountain Biking Team, Queen's Climbing Club Multi-disciplinary research in synthetic organic chemistry (method development and synthesis of new heteroaromatic molecules) and molecular biology (enzyme structure, function and mechanism), in the laboratories of Dr. Victor Snieckus and Dr. David Zechel.Specific Projects:• Developed and demonstrated an effective in vivo method for indolocarbazole production in E. coli.• Applied the in vivo approach in order to delineate the origin of unique chemoselective outcomes of related… Visualizza altro Multi-disciplinary research in synthetic organic chemistry (method development and synthesis of new heteroaromatic molecules) and molecular biology (enzyme structure, function and mechanism), in the laboratories of Dr. Victor Snieckus and Dr. David Zechel.Specific Projects:• Developed and demonstrated an effective in vivo method for indolocarbazole production in E. coli.• Applied the in vivo approach in order to delineate the origin of unique chemoselective outcomes of related indolocarbazole biosynthetic enzymes through enzyme active site manipulation (mutagenesis).• Developed a synthetic methodology for the efficient preparation of a library of heterocyclic enzyme substrate analogues anticipated to be useful mechanistic probes of enzyme catalytic pathways.• Commenced a synthetic methodology project designed to extend the utility of directed ortho metalation chemistry to the regioselective functionalization of the indole heteroaromatic framework. Meno dettagli