Dr. Baplu Rai

Dr. Baplu Rai

Research Assistant

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location of Dr. Baplu RaiMünster, North Rhine-Westphalia, Germany

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  • Timeline

  • About me

    Postdoc / Immunology / Translational Research / Teamwork

  • Education

    • WhiteHouse Int'l College

      2007 - 2012
      Bachelor of Technology in Biotechnology Biotechnology

      I completed modules in cell and molecular biology, biochemistry, immunology, and cancer biology. My bachelor's thesis involved optimizing and scaling up lipase production from Aspergillus niger. Please refer to the publication for a summary of my thesis.

    • University of Erlangen-Nuremberg

      2017 - 2024
      Doctor of Philosophy - PhD Infection immunology

      Under the guidance of Prof. Dr. Christian Bogdan and PD. Dr. Ulrike Schleicher, my research has focused on examining the role of Arginase 1 in chronic cutaneous leishmaniasis. Through my work, I have discovered the unexpected role of Arginase 1 in the differentiation dynamics of monocytes that act as replicative niches during chronic infection. Additionally, I was thrilled to have been involved in the initial phase of a clinical trial in Tabasco, Mexico, which was based on my PhD research… Show more Under the guidance of Prof. Dr. Christian Bogdan and PD. Dr. Ulrike Schleicher, my research has focused on examining the role of Arginase 1 in chronic cutaneous leishmaniasis. Through my work, I have discovered the unexpected role of Arginase 1 in the differentiation dynamics of monocytes that act as replicative niches during chronic infection. Additionally, I was thrilled to have been involved in the initial phase of a clinical trial in Tabasco, Mexico, which was based on my PhD research findings. My interests lie in exploring areas related to innate immunity, myeloid cells, infection immunology, and immune metabolism. Thus far, I have co-authored three papers and have had the opportunity to present my research work through oral and poster presentations at various international conferences. Show less

    • University of Erlangen-Nuremberg

      2014 - 2016
      MSc Molecular Science Molecular Life Science

      Master Thesis:Investigated the plasma membrane proton pump (PMA2) promoter region of Colletotrichum Higginsianum, a plant pathogenic fungi, through in locus promoter truncation. This was achieved using cloning, fungal transformation, and homologous recombination. I also performed in silico analysis to predict promoter elements, mutant screening using PCR, and fluorescence microscopy and assessed the virulence phenotype of mutants in A. thaliana model.

  • Experience

    • Asian Institute of Technology and Management

      Sept 2012 - Aug 2014
      Research Assistant

      As a part of the Department of Biotechnology, I instructed Bachelor students in the lab according to the academic curriculum. Additionally, I secured two research grants from the Ministry of Education and the University Grants Commission.

    • University of Erlangen-Nuremberg

      Apr 2015 - Mar 2017
      Research Assistant @Department of Pharmaceutical Biology, FAU Erlangen, Prof. Dr. Wolfgang Kreis Lab

      I worked in a tissue culture lab, responsible for maintaining tissue culture stocks, performing protein expression profiling using ImageJ, and maintaining and calibrating lab instruments

    • Universitätsklinikum Erlangen

      May 2017 - now

      I completed my PhD at the Laboratory for Innate Immunity and Leishmania Research under the mentorship of Prof. Dr. Christian Bogdan and PD Dr. Ulrike Schleicher. My research focused on the novel role of Arginase 1 in the differentiation dynamics of monocytes, which serve as replicative niches during chronic infections. This work led to the initiation of on-site clinical studies in Tabasco, Mexico.I possess extensive experience in a range of scientific techniques, including:Immunology: FACS, ELISAMolecular Biology: qPCR, Western BlotMicroscopy: Fluorescence, Confocal, Spinning Disc, Thunder, KeyenceImmunometabolism: Seahorse AssayMetabolomics: LC-Mass Spectrometry, MetaboAnalyst softwareTranscriptomics: Single-cell sequencing (10x Genomics, BD Rhapsody), library preparation, count matrix generation, clustering, and trajectory analysis using R.My research interests span innate immunity, myeloid cells, infection immunology, and immune metabolism. I have co-authored three peer-reviewed papers and presented my findings at several international conferences. Show less

      • Postdoctoral Researcher @Innate Immunity and Leishmania Research Lab

        Apr 2024 - now
      • PhD @Institute of Microbiology, Immunology & Hygiene, UK-Erlangen, Prof. Dr. Christian Bogdan Lab

        May 2017 - Mar 2024
    • Facultad de Medicina - UNAM

      Aug 2022 - Aug 2022
      Researcher @Immunoparasitology Laboratory, Prof. Dr. Ingeborg Becker Lab

      I conducted a week-long research trip to launch a randomized double-blinded phase 2a/2b clinical trial on cutaneous leishmaniasis. While in Tabasco, Villahermosa, I collaborated with local doctors affiliated with the University of Tabasco, UJAT, to collect samples from cutaneous leishmaniasis patients. These samples were processed at UNAM in Mexico City and then analyzed at the Microbiology Institute, University Clinic, Erlangen.

  • Licenses & Certifications

    • OMERO seminar

      Dr. Benjamin Schmid, Optical Imaging Centre Erlangen
      Dec 2017
    • Advanced ImageJ/Fiji course

      Dr Benjamin Schmid, Optical Imaging Centre Erlangen
      Nov 2017
    • FELASA B

      PETZ Erlangen
      Sept 2017
    • Advanced Spinning Disc Imaging

      Dr. Philip Tripal , Optical Imaging Centre Erlangen
      Aug 2017
  • Honors & Awards

    • Awarded to Dr. Baplu Rai
      DGfI Travel Grant German Society for Immunology (DGfI) Jul 2023 I got a DGfI travel grant to attend Joint Meeting SFI & DGfI 2023, Strasbourg, France.
    • Awarded to Dr. Baplu Rai
      Abschluss Stipendium (Final year thesis scholarship) FAU-Erlangen collaboration with Bayern state
    • Awarded to Dr. Baplu Rai
      Academic excellence award Department of Biotechnology
  • Volunteer Experience

    • To spread the knowledge of environment protection.

      Issued by GDUFS, China on Nov 2013
      GDUFS, ChinaAssociated with Dr. Baplu Rai