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Baplu Rai

Baplu rai

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location of Baplu RaiErlangen, Bayern, Deutschland
Phone number of Baplu RaiView Mobile No.
Followers of Baplu Rai1198 followers

  • Timeline

  • About me

    Infection Immunologist @Prof. Christian Bogdan Lab

  • Education

    • Whitehouse int'l college

      -
      Bachelor of technology in biotechnology biotechnology

      I completed modules in cell and molecular biology, biochemistry, immunology, and cancer biology. My bachelor's thesis involved optimizing and scaling up lipase production from Aspergillus niger. Please refer to the publication for a summary of my thesis.

    • University of erlangen-nuremberg

      -
      Doctor of philosophy - phd infection immunology

      Under the guidance of Prof. Dr. Christian Bogdan and PD. Dr. Ulrike Schleicher, my research has focused on examining the role of Arginase 1 in chronic cutaneous leishmaniasis. Through my work, I have discovered the unexpected role of Arginase 1 in the differentiation dynamics of monocytes that act as replicative niches during chronic infection. Additionally, I was thrilled to have been involved in the initial phase of a clinical trial in Tabasco, Mexico, which was based on my PhD research… Mehr anzeigen Under the guidance of Prof. Dr. Christian Bogdan and PD. Dr. Ulrike Schleicher, my research has focused on examining the role of Arginase 1 in chronic cutaneous leishmaniasis. Through my work, I have discovered the unexpected role of Arginase 1 in the differentiation dynamics of monocytes that act as replicative niches during chronic infection. Additionally, I was thrilled to have been involved in the initial phase of a clinical trial in Tabasco, Mexico, which was based on my PhD research findings. My interests lie in exploring areas related to innate immunity, myeloid cells, infection immunology, and immune metabolism. Thus far, I have co-authored two papers and have had the opportunity to present my research work through oral and poster presentations at various international conferences. Weniger anzeigen

    • University of erlangen-nuremberg

      -
      Msc molecular science molecular life science

      Master Thesis:Investigated the plasma membrane proton pump (PMA2) promoter region of Colletotrichum Higginsianum, a plant pathogenic fungi, through in locus promoter truncation. This was achieved using cloning, fungal transformation, and homologous recombination. I also performed in silico analysis to predict promoter elements, mutant screening using PCR, and fluorescence microscopy and assessed the virulence phenotype of mutants in A. thaliana model.

  • Experience

    • Asian institute of technology and management

      Sept 2012 - Aug 2014
      Research assistant

      As a part of the Department of Biotechnology, I instructed Bachelor students in the lab according to the academic curriculum. Additionally, I secured two research grants from the Ministry of Education and the University Grants Commission.

    • University of erlangen-nuremberg

      Apr 2015 - Jan 2017
      Research assistant @department of pharmaceutical biology, fau erlangen, prof. dr. wolfgang kreis lab

      I worked in a tissue culture lab, responsible for maintaining tissue culture stocks, performing protein expression profiling using ImageJ, and maintaining and calibrating lab instruments

    • University of erlangen-nuremberg

      Jan 2017 - Apr 2024
      Phd @institute of microbiology, immunology & hygiene, uk-erlangen, prof. dr. christian bogdan lab

      I did my PhD from the Laboratory for Innate Immunity and Leishmania Research under the guidance of Prof. Dr. Christian Bogdan and PD. Dr. Ulrike Schleicher. During my research, I discovered the unexpected role of Arginase 1 in the differentiation dynamics of monocytes, which act as replicative niches during chronic infections. As a result of my findings, a phase 2 trial was initiated in Tabasco, Mexico.I have experience in various scientific techniques, including immunology (FACS, ELISA), molecular biology (qPCR, Western Blot), microscopy (Fluorescence, Confocal, Spinning disc, Thunder, Keyence), immunometabolism (Seahorse assay), metabolomics (LC-Mass spectrometry, MetaboAnalyst software), and transcriptomics (10x and BD Rhapsody single-cell sequencing platform, library preparation, count matrix generation, clustering, and trajectory analysis using R program).My research interests include innate immunity, myeloid cells, infection immunology, and immune metabolism. I have co-authored two papers and presented my work at international conferences. Weniger anzeigen

    • Facultad de medicina - unam

      Aug 2022 - Aug 2022
      Researcher @immunoparasitology laboratory, prof. dr. ingeborg becker lab

      I conducted a week-long research trip to launch a randomized double-blinded phase 2a/2b clinical trial on cutaneous leishmaniasis. While in Tabasco, Villahermosa, I collaborated with local doctors affiliated with the University of Tabasco, UJAT, to collect samples from cutaneous leishmaniasis patients. These samples were processed at UNAM in Mexico City and then analyzed at the Microbiology Institute, University Clinic, Erlangen.

    • Innate immunity and leishmania research lab: institute of microbiology, immunology & hygiene

      Apr 2024 - now
      Postdoctoral researcher

  • Licenses & Certifications

    • Omero seminar

      Dr. benjamin schmid, optical imaging centre erlangen
      Jan 2017

    • Advanced imagej/fiji course

      Dr benjamin schmid, optical imaging centre erlangen
      Nov 2017

    • Felasa b

      Petz erlangen
      Sept 2017

    • Advanced spinning disc imaging

      Dr. philip tripal , optical imaging centre erlangen
      Aug 2017

  • Honors & Awards

    • Awarded to Baplu Rai
      DGfI Travel Grant German Society for Immunology (DGfI) Juli 2023 I got a DGfI travel grant to attend Joint Meeting SFI & DGfI 2023, Strasbourg, France.
    • Awarded to Baplu Rai
      Abschluss Stipendium (Final year thesis scholarship) FAU-Erlangen collaboration with Bayern state
    • Awarded to Baplu Rai
      Academic excellence award Department of Biotechnology

  • Volunteer Experience

    • To spread the knowledge of environment protection.

      Issued by GDUFS, China on Nov 2013
      GDUFS, ChinaAssociated with Baplu Rai