Jonathan Goodwin, PhD, CAPM

Experience

• 

  Pro2 Respiratory Svc

  Jan 2007 - Jan 2009

  CSR/ Case Manager

  Liaison between high-tech (high need) patients and licensed respiratory therapists.

• 

  Thomas Jefferson University

  Aug 2009 - Jun 2015

  • Designed and performed preclinical studies examining mechanisms of crosstalk between the androgen receptor and the DNA damage response that drive prostate cancer progression and therapeutic resistance• Designed and performed preclinical studies characterizing the role of DNA damage factors in transcriptional regulation, identifying the DNA-dependent protein kinase (DNA-PK) as a genome wide regulator of transcriptional pathways that drive cancer progression and metastatic development• Performed preclinical studies evaluating efficacy of novel DNA-PK inhibitors as single agents and combination therapies in late stage prostate cancer• Contributed to multiple collaborative studies on hormone receptor-mediated signaling pathways driving cell cycling and cancer progression, DNA damage and repair, and therapeutic response and resistance• Co-mentor for one graduate student Show less

  • Postdoctoral Research Fellow

    Apr 2015 - Jun 2015

  • PHD Graduate Student, Biochemistry & Molecular Pharmacology

    Aug 2009 - Apr 2015
• 

  NMS Labs

  Jun 2015 - Aug 2017

  • Contributed to design, development and validation of immunoassay and cell-based methods in a regulated environment for multiple applications, including biologic quantitation, neutralizing antibody detection and cancer biomarker screening • Directly accounted for daily experimental design, execution, documentation, data processing and results reporting• Identified novel projects targeting unmet clinical needs for consideration as new products for development• Supervised one direct report Show less

  • R&D Scientist II

    Nov 2016 - Aug 2017

  • Clinical Research Associate II

    Jun 2015 - Nov 2016
• 

  Teva Pharmaceuticals

  Aug 2017 - now

  • Developed immunogenicity assessment strategies through design, validation, and implementation of anti-drug antibody methods in a regulated environment with adherence to regulatory guidelines• Managed sample analysis and documentation from assay run planning and execution through data analysis and summary• Contributed to creation of method development, assay validation, and sample analysis reports

  • Associate Director, Critical Reagents

    Jun 2024 - now

  • Senior Scientist

    Jun 2021 - now

  • Scientist

    Aug 2017 - Jun 2021