Nicholas Butler

Experience

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  University of Wollongong

  Apr 2019 - Aug 2019

  Developed interactive lecture content for a new undergraduate second-year general chemistry subject (CHEM200), focused on understanding the chemistry of day-to-day life. This was developed using H5P for Moodle compatibility, and included interactive HTML5 modules on natural products, drug discovery and the pharmaceutical industry; antibiotics, their mode of action, and antibiotic resistance; and the environment, water chemistry and pollution. Supervised and led lab classes and tutorials for various undergraduate chemistry courses. These include leading numerous lab courses for first-year general chemistry classes averaging 50-60 students per class, and both second- and third-year courses in general organic chemistry, advanced organic chemistry and organic synthesis, food chemistry, and analytical and environmental chemistry, averaging between 20-40 students per class. Developed synthetic chemistry methodologies for the diversity-oriented synthesis of bioactive heterocycles from indigo dye. This included cascade reactions of indigo with multifunctional propargylic and strained-ring electrophiles, and for desymmetrisation reactions of indigo with substituted organometallic reagents for the synthesis of antiplasmodial 3-substituted-[1H,3'H]-2,2'-diindol-3'-ones. Developed methods for the oxidative diamination of alkenes.

  • Content Developer

    Jul 2019 - Aug 2019

  • Laboratory Demonstrator/Tutor

    Mar 2015 - Aug 2019

  • PhD Candidate

    Mar 2015 - Aug 2019

  • Research Assistant

    Apr 2019 - Jun 2019
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  Children's Cancer Institute

  Sept 2019 - Dec 2021

  Technical Officer

  Chemistry subject-matter expert, providing technical support and consulting services to researchers and external partners on handling and storage of hazardous materials, and implementation of CCI’s chemical register.Management of on-demand buffer service for researchers, including procurement, preparation, and QA/QM of chemicals, consumables, and culture media/reagents for in vitro and in vivo drug screening, cell-based assays, and general biochemical and molecular biology workflows.Ensuring Institute adherence to WHS legislation for the use of hazardous materials, as well as development and review of SWPs, risk assessments, and technical reports.Assisting with the ongoing design of new drug discovery, nanomedicine and general laboratory spaces within the planned Comprehensive Children’s Cancer Centre.Coordination of PC2 laboratory hazardous waste disposal streams.Processing of patient blood and marrow samples for biobanking purposes. Show less

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  NSW Health Pathology

  Jan 2022 - now

  Scientific Officer (Chemical Criminalistics Unit)

  Scientific officer with the Chemical Criminalistics Unit, specialising in detection and analysis of riot control agents, explosives and unknown materials.