Anna Stanley-Smith

Anna stanley-smith

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  • Timeline

  • About me

    VP of Quality at Isomerase Therapeutics Ltd.

  • Education

    • University of warwick

      2003 - 2006
      Phd chemistry (molecular biology)

      Activities and Societies: Computing, badminton, ten-pin bowling. (Ten-pin Bowling Club, University of Warwick – Half Colours and Club Colours. Exec. member 2000-06.) “Investigating the Prodiginine Biosynthetic Pathway in S. coelicolor” under the supervision of Professor Greg Challis. Use of REDIRECT PCR-Targeting Technology to create gene knockouts in the actinomycete S. coelicolor. Gene cloning and disruption. Genetic and sequence analysis. Analysis of antibiotic and intermediate production by wild type/mutant strains by LC-MS and LC-MS/MS. Cross-feeding of strains, complementation by co-synthesis and feeding of synthetic intermediates, leading to… Show more “Investigating the Prodiginine Biosynthetic Pathway in S. coelicolor” under the supervision of Professor Greg Challis. Use of REDIRECT PCR-Targeting Technology to create gene knockouts in the actinomycete S. coelicolor. Gene cloning and disruption. Genetic and sequence analysis. Analysis of antibiotic and intermediate production by wild type/mutant strains by LC-MS and LC-MS/MS. Cross-feeding of strains, complementation by co-synthesis and feeding of synthetic intermediates, leading to elucidation of the biosynthetic pathway. Show less

  • Experience

    • Biotica

      Jan 2007 - Nov 2012

      - Management of internal compound screening collection (NovoPT Polyketides)- Management of QMS for outsourced work- Management of internal databases (FileMaker Pro), company intranet and web site- Management of company Electronic Lab Notebook (ELN) system and compliance- General IT support within company- Multidisciplinary Scientist (Chemistry, Molecular Biology, Informatics)- Managed company move to new state-of-the-art custom built lab and office space- Liaison between scientists of different disciplines and management- Ad hoc IP and administrative support Show less Responsible for the construction, management, upkeep and expansion of a chemical library of polyketide compounds as an entry point for new projects into the company. Development of company hit-to-lead documentation. Management and expansion of corporate databases, including implementation of a barcoding system to track inventory. Sourcing, introduction and maintenance of a new Electronic Lab Notebook (ELN) system for the company. General IT management for the company, including training staff and daily troubleshooting. Liaison between scientists of different disciplines and management. Ad hoc administrative IP support. Show less

      • Project Manager

        Jun 2011 - Nov 2012
      • Project Manager, NovoPT

        Mar 2010 - May 2011
      • Research Scientist (Molecular Biology)

        Jan 2007 - Feb 2010
    • Isomerase

      Nov 2013 - now

      Leads and manages collaborations with external clients, plus proprietary internal projectsQuality Manager (ISO9001:2015)Manages/coordinates company IT and supportManages company databasesCompound supplySupports company strategy Leads and manages collaborations with external clients, plus proprietary internal projectsQuality Manager (ISO9001:2015)Manages/coordinates company IT and supportManages company databasesCompound supplySupports company strategy Manages external collaborations and internal research programmes, using experience in chemistry, biology and IT, to drive multidiscipliniary teams to discover novel natural product drugs in a variety of different therapeutic areas and also for crop protection products for agriculture.

      • VP of Quality

        Jan 2024 - now
      • VP of Projects

        Oct 2020 - Feb 2024
      • Project Leader

        Nov 2013 - Oct 2020
  • Licenses & Certifications

    • Member of the royal society of chemistry

      Royal society of chemistry
      Mar 2021
      View certificate certificate