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Friederike Fehr

Friederike Fehr

Office of the Chief Executive (OCE) Postdoctoral Fellow

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  • Timeline

  • About me

    Associate Director, QbD Lifecycle Management, Process Engineering at CSL Behring

  • Education

    • The University of Göttingen

      2007 - 2011
      Dr. rer. nat (PhD science) Peptide Chemistry

      The conducted PhD thesis explores the introduction of artificial amino acids into an entire zinc finger protein to incorporate a cleavage tool into a DNA binding biomolecule. The two main synthetic strategies used were Fmoc solid phase peptide synthesis (SPPS) and protein expression to achieve this goal. The sequence which encodes two zinc fingers (60aa) was cloned into a specific vector releasing the protein as C-terminal thioester during purification. A set of peptides were synthesised… Show more The conducted PhD thesis explores the introduction of artificial amino acids into an entire zinc finger protein to incorporate a cleavage tool into a DNA binding biomolecule. The two main synthetic strategies used were Fmoc solid phase peptide synthesis (SPPS) and protein expression to achieve this goal. The sequence which encodes two zinc fingers (60aa) was cloned into a specific vector releasing the protein as C-terminal thioester during purification. A set of peptides were synthesised composed of the third zinc finger (30aa) with an N-terminal cysteine and several different artifical amino acids included into the sequence. Subsequent ligation lead to 6 different poly peptides which were analysed by ESI mass spectrometry and CD spectroscopy. Also organic synthesis was used to prepare artificial amino acid building blocks to be incorporated in additional poly peptides. Show less

    • Friedrich Schiller University Jena

      2001 - 2004
      BSc Chemistry

    • University of Strathclyde

      2004 - 2005
      BSc Forensic and Analytical Chemistry

      My Bachelor thesis in 'Forensic and Analytical Chemistry' entitled 'Extraction of DNA from bone' dealt with the question how we can enhance the extraction of DNA from bone material. For that purpose PCR and capillary electrophoresis were used to compare several commercially available extraction kits.

    • The University of Göttingen

      2005 - 2007
      MSc Chemistry

      Activities and Societies: Student Union Organic synthesis of artificial amino acid building blocks for solid phase peptide synthesis (Fmoc). Metal binding bisimidazole moieties were introduced into the side chain of natural amino acids in order to create novel metal binding sites in zinc finger protein Zif268, a DNA binding transcription factor.

  • Experience

    • CSIRO

      Oct 2011 - Apr 2015
      Office of the Chief Executive (OCE) Postdoctoral Fellow

      I have been involved in several projects at the interface of chemistry and biology using my expertise in peptide chemistry and protein ligation to support several teams. I have been also involved in a project aiming to semi-synthesise short homogeneously glycosilated proteins by chemically modifying recombinant expressed proteins.As intern of the Business Development Course 'Molecules to Medicine' and as part of the 'on-the-job-training' I have developed a business plan for a project in a different scientific area. This experience has provided me with a new skill set and sparked my interest to explore the business side of projects. Show less

    • Cancer Therapeutics CRC (CTx)

      May 2014 - Jun 2015
      Business Development training - Molecules2Medicine

      An on-the-job training and mentoring initiative for early career researchers in translation and commercialisation of biomedical advances sponsored by the CRC - Cancer Therapeutics.On completion of the program I developed an in depth analysis of a technology. Based on the completed detailed competitive analysis and path to market for the technology the internal business development unit at CSIRO assessed the commercial viability of the project and steps are taken to pursue this goal.

    • RMIT University

      Sept 2016 - Mar 2019

      I assessed technologies and compiled technical and market analysis reports looking at the competitive landscape to identify the best fit for a commercialisation pathway.Once identified I further developed implementation strategies and we pursued those as a team talking to potential partners or licensees to discuss commercial terms Supported the Research Initiatives team in coordinating industry led grant applicationsCase management of seed funded project

      • Research Analyst - Tech transfer&Commercialisation

        Jan 2017 - Mar 2019

      • Case Manager-Research Initiatives

        Sept 2016 - Jan 2017

    • CSL

      Mar 2019 - now

      Leading the MS&T Bulk Value Stream, my team supports all plasma product bulk manufacturing processes with scientific and technical expertise. This support goes way beyond deviation and CAPA management and we are excited to support improving our processes with a knowledge based approach relying on data analysis and scientific expertise to improve outcomes for our patients. R&D subject matter expert and lead for a blood plasma derived product, supporting manufacturing with scientific expertise in process validation activities and commercial manufacturing as well as trouble-shooting and deviation management.Innovation lead for Technical Operations to identify and explore innovative improvement ideas.

      • Associate Director, Global Lead QbD Lifecycle Management, Process Engineering

        May 2023 - now

      • Manufacturing Science and Technology Lead, Senior Manager, Process Engineering

        Mar 2021 - May 2023

      • Senior Scientist/Manager R&D Technical Operations

        Dec 2019 - Mar 2021

      • Scientist, R&D Technical Operations

        Mar 2019 - Dec 2019

  • Licenses & Certifications

    • Innovation Management on Coursera

      Erasmus University Rotterdam
      May 2018
      View certificate certificate

  • Honors & Awards

    • Awarded to Friederike Fehr
      Travel Grant Australian Peptide Association Sep 2013
    • Awarded to Friederike Fehr
      Poster award - early postdoctoral fellow CSIRO Mar 2012
    • Awarded to Friederike Fehr
      Office of the Chief Executive Postdoctoral Fellowship CSIRO Oct 2011
    • Awarded to Friederike Fehr
      PhD scholarship International Graduate School German Research Council (DFG) Oct 2009
    • Awarded to Friederike Fehr
      Erasmus Stipend German Academic Exchange Service (DAAD) Sep 2004

  • Volunteer Experience

    • Conference organising committee member

      Issued by KCA - Knowledge Commercialisation Australasia Ltd on Jan 2019
      KCA - Knowledge Commercialisation Australasia LtdAssociated with Friederike Fehr

    • Co-Chair, Postdoc committee

      Issued by CSIRO on Oct 2012
      CSIROAssociated with Friederike Fehr

    • Member, Postdoc committee

      Issued by CSIRO on Oct 2011
      CSIROAssociated with Friederike Fehr

    • PhD representative, Finance committee

      Issued by The University of Göttingen on Oct 2008
      The University of GöttingenAssociated with Friederike Fehr

    • Co-Chair, IRTG 1422

      Issued by The University of Göttingen on Oct 2008
      The University of GöttingenAssociated with Friederike Fehr

    • Member, Student union

      Issued by The University of Göttingen on Oct 2005
      The University of GöttingenAssociated with Friederike Fehr