Sarah Johnson

Sarah johnson

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location of Sarah JohnsonSilver Spring, Maryland, United States
Followers of Sarah Johnson411 followers
  • Timeline

  • About me

    Senior Biologist/ CMC Product Quality Reviewer at FDA

  • Education

    • Randolph-macon woman's college

      2003 - 2007
      Bachelor of science (b.s.) general biology with an emphasis in cell and developmental biology
    • University of california, los angeles

      2008 - 2014
      Doctor of philosophy (phd) molecular biology
  • Experience

    • Randolph college

      Aug 2004 - May 2007
      Ethyl center math and science tutor

      Tutored undergraduate peers in introductory and upper-level Biology courses-College Reading and Learning Association (CRLA) certified

    • National institutes of health

      Jun 2007 - Aug 2008
      Irta post-baccalaureate fellow

      Collaborated with a team of IRTA post-baccalaureate and post-doctoral fellows to establish protocols for the Salivary Gland Molecular Anatomy Project: Salivary Gland Gene Expression Database (http://sgmap.nidcr.nih.gov/sgmap/sgexp.html) Publications:Musselmann K, Green JA, Sone K, Hsu JC, Bothwell IR, Johnson, SA, Harunaga JS, Wei Z, Yamada KM.(2011). Atlas of Early Salivary Gland Gene Expression Identifies a New Regulator of Branching. Journal of Dental Research. 90(9); 1078-84

    • Ucla molecular biology institute

      Sept 2008 - Dec 2014
      Graduate student researcher

      Thesis work in Dr. Arnie Berk's laboratory studying the molecular interactions that regulate transcription in mammalian cells. Specifically, I characterized host cell chromatin compaction by P300, pRB, and small e1a using fluorescence microscopy and protein biochemistry.Publications: Ferrari, R* , Gou, D*, Jawdekar, G*, Johnson, SA*, Nava, M*, Su, T*, Yousef, A*, Zemke, NR*, Pellegrini, M, Kurdistani, SK, Berk, AJ (2014) CBP/P300 function in repression as well as activation regulated by adenovirus small e1a. Cell Host & Microbe, in press.*Co-first authors in alphabetical order.Business of Science Center, Venture Team, 2014Advanced Degree Consulting Club Case Competition, 2013Cell and Molecular Biology (C&MB) Training Program Trainee, 2009-2012 Show less

    • Fda

      Feb 2015 - now

      Product quality reviewer for biologics in the Office of Biotechnology ProductsPublications:1. Brown MR, Burnham MS, Lute SC, Johnson SA, Walsh AA, Brorson KA, Roush DJ. Defining the Mechanistic Binding of Viral Particles to a Multi-Modal Anion Exchange Resin. Biotechnol Prog. 2018 Apr 30. doi: 10.1002/btpr.2648. 2. Brown MR, Burnham MS, Johnson SA, Lute SC, Brorson KA, Roush DJ. Evaluating the effect of in-process material on the binding mechanisms of surrogate viral particles to a multi-modal anion exchange resin. J Biotechnol. 2018 Feb 10; 267:29-35. Show less Modernization of Viral Safety Approaches and Technology for Monoclonal AntibodiesPublications:1. Johnson SA*, Walsh A*, Brown MB, Burnham, M, Lute SC, Roush D, Brorson K. The step-wise framework for the development of a chromatography-based hydrophobicity assay for viral particles. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:430-437. *Co-first authors in alphabetical order2. Johnson SA, Brorson KA, Frey DD, Dhar AK, Cetlin DA. Characterization of Non-Infectious Virus-Like Particle Surrogates for Viral Clearance Applications. Appl Biochem Biotechnol. 2017 Sep; 183(1):318-331.3. Brown MR, Johnson SA, Brorson KA, Lute SC, and Roush DJ. A step-wise approach to define binding mechanisms of surrogate viral particles to multi-modal anion exchange resin in a single solute system. Biotechnol Bioeng. 2017 Jul;114(7):1487-1494.4. Wang J, Johnson S, Brown M, Lute S, Agarabi C, Dabrazhynetskaya A, Chizhikov V, and Brorson K. Mycoplasma clearance and risk analysis in a model bioprocess. PDA J Pharm Sci Technol. 2017 Mar-Apr;71(2):99-114. Show less

      • Senior Biologist

        Nov 2021 - now
      • Biologist

        Sept 2016 - now
      • ORISE Post-doctoral Fellow

        Feb 2015 - Sept 2016
  • Licenses & Certifications