Sarah Johnson

Experience

• 

  Randolph College

  Aug 2004 - May 2007

  Ethyl Center Math and Science Tutor

  Tutored undergraduate peers in introductory and upper-level Biology courses-College Reading and Learning Association (CRLA) certified

• 

  National Institutes of Health

  Jun 2007 - Aug 2008

  IRTA Post-baccalaureate Fellow

  Collaborated with a team of IRTA post-baccalaureate and post-doctoral fellows to establish protocols for the Salivary Gland Molecular Anatomy Project: Salivary Gland Gene Expression Database (http://sgmap.nidcr.nih.gov/sgmap/sgexp.html) Publications:Musselmann K, Green JA, Sone K, Hsu JC, Bothwell IR, Johnson, SA, Harunaga JS, Wei Z, Yamada KM.(2011). Atlas of Early Salivary Gland Gene Expression Identifies a New Regulator of Branching. Journal of Dental Research. 90(9); 1078-84

• 

  UCLA Molecular Biology Institute

  Sept 2008 - Dec 2014

  Graduate Student Researcher

  Thesis work in Dr. Arnie Berk's laboratory studying the molecular interactions that regulate transcription in mammalian cells. Specifically, I characterized host cell chromatin compaction by P300, pRB, and small e1a using fluorescence microscopy and protein biochemistry.Publications: Ferrari, R* , Gou, D*, Jawdekar, G*, Johnson, SA*, Nava, M*, Su, T*, Yousef, A*, Zemke, NR*, Pellegrini, M, Kurdistani, SK, Berk, AJ (2014) CBP/P300 function in repression as well as activation regulated by adenovirus small e1a. Cell Host & Microbe, in press.*Co-first authors in alphabetical order.Business of Science Center, Venture Team, 2014Advanced Degree Consulting Club Case Competition, 2013Cell and Molecular Biology (C&MB) Training Program Trainee, 2009-2012 Show less

• 

  FDA

  Feb 2015 - now

  Product quality reviewer for biologics in the Office of Biotechnology ProductsPublications:1. Brown MR, Burnham MS, Lute SC, Johnson SA, Walsh AA, Brorson KA, Roush DJ. Defining the Mechanistic Binding of Viral Particles to a Multi-Modal Anion Exchange Resin. Biotechnol Prog. 2018 Apr 30. doi: 10.1002/btpr.2648. 2. Brown MR, Burnham MS, Johnson SA, Lute SC, Brorson KA, Roush DJ. Evaluating the effect of in-process material on the binding mechanisms of surrogate viral particles to a multi-modal anion exchange resin. J Biotechnol. 2018 Feb 10; 267:29-35. Show less Modernization of Viral Safety Approaches and Technology for Monoclonal AntibodiesPublications:1. Johnson SA*, Walsh A*, Brown MB, Burnham, M, Lute SC, Roush D, Brorson K. The step-wise framework for the development of a chromatography-based hydrophobicity assay for viral particles. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:430-437. *Co-first authors in alphabetical order2. Johnson SA, Brorson KA, Frey DD, Dhar AK, Cetlin DA. Characterization of Non-Infectious Virus-Like Particle Surrogates for Viral Clearance Applications. Appl Biochem Biotechnol. 2017 Sep; 183(1):318-331.3. Brown MR, Johnson SA, Brorson KA, Lute SC, and Roush DJ. A step-wise approach to define binding mechanisms of surrogate viral particles to multi-modal anion exchange resin in a single solute system. Biotechnol Bioeng. 2017 Jul;114(7):1487-1494.4. Wang J, Johnson S, Brown M, Lute S, Agarabi C, Dabrazhynetskaya A, Chizhikov V, and Brorson K. Mycoplasma clearance and risk analysis in a model bioprocess. PDA J Pharm Sci Technol. 2017 Mar-Apr;71(2):99-114. Show less

  • Senior Biologist

    Nov 2021 - now

  • Biologist

    Sept 2016 - now

  • ORISE Post-doctoral Fellow

    Feb 2015 - Sept 2016