Harish Dixit, Ph.D.

Experience

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  Prosetta Biosciences Inc

  May 2007 - Aug 2007

  Intern

  -This internship project studied the causal relationship between prostatic acid phosphatase (PAcP) and prostate cancer-Developed process flow to purify PAcP from seminal fluid samples, which would be used to generate anti-PAcP antibodies-Proposed the use of these antibodies to (1) identify specific regions of PAcP protein that are surface exposed; (2) correlate expression levels of surface proteins at different stages of cancer progression; (3) use them as a predictive biomarker and therapeutic Show less

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  Indian Institute of Science (IISc)

  Jun 2010 - Aug 2010

  Undergraduate Research Assistant

  -Undergraduate Research Assistant working in the Gundiah Lab under Dr. Namrata Gundiah-This project involved the identification of the most prominent mutated genetic sequences associated with Marfan’s Syndrome in the Indian population-DNA was purified from blood samples of patients with Marfan’s syndrome-Sequences known to be associated with this disease were found from scientific literature-The patient DNA was then fragmented and copied using PCR-These fragments were then sequenced and used to create a database for comparisons of such sequences between multiple patients, noting for any common abnormalities-The preliminary work for this project was presented by the Principal Investigator at the World Congress on Biomechanics, Singapore, 2010. Show less

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  University of California, Berkeley

  Aug 2010 - May 2012

  Undergraduate Research Assistant

  -Undergraduate Research Assistant working in the Anderson Lab under Dr. J. Christopher Anderson-The primary focus of this research project was on the design and implementation of tumor killing bacteria-These bacteria were cultured by the graduate researcher, and were then injected into subcutaneous tumors in nude mice by the undergraduate research assistants-The tumors were then excised from the mice at different time points, homogenized, and plated on agar plates to assess for bacterial efficacy against the tumor cells Show less

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  Novellus Systems acquired by Lam Research Corporation

  Jun 2011 - Aug 2011

  Intern

  -Worked in the Integrated Metals Business Unit on PVD and ALD metal deposition processes used for integrated circuit production-Understood the hardware used in PVD high ionization process using hollow cathode magnetron for TaN/Ta barrier and Cu seed deposition and Atomic Layer Deposition of TaN barrier using metal-organic precursor-Understood the details of the processing steps and created a throughput model to calculate the number of silicon wafers that could be produced in a day using a certain set of process recipes Show less

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  University of California, Riverside

  Sept 2014 - Aug 2018

  Graduate Student Researcher in the Biomedical Microdevices Laboratory under Dr. Masaru P. RaoProject: Ultrahigh Throughput (UHT) Mechanoporation Microdevice for Cell Therapy Applications -Lead Graduate Researcher on the $500k project-Fabricated and tested a silicon micro device for transient cell membrane poration for ultrahigh throughput intracellular delivery-Developed and implemented novel testing apparatuses and protocols-Designed a custom device housing capable of integrating with an upright fluorescence microscope for precise device control, and real time monitoring of cell testing-Tested device efficiency using a range of fluorescent molecules and functional plasmids, some used in clinical trials for T-Cell Immunotherapies at City of Hope National Medical Center-Implemented a preliminary pressure-controlled flow system using LabVIEW to allow for a pressure ceiling during device operation as well as real time monitoring of pressure drops to further increase device efficiency-Currently developing a confocal imaging protocol to image transient membrane pores in mechanoporated cells fixed via glutaraldehydeConference Oral Presentations: -7th International Conference on Microtechnology in Medicine and Biology (MMB), Marina Del Rey, CA (2013)-ASME International Mechanical Engineering Congress and Exposition (IMECE), San Diego, CA (2013)-Seminar in The Department of Mechanical Engineering, Riverside, CA (2014)-ASME 3rd Global Congress on Nanoengineering for Medicine and Biology (NEMB), San Francisco, CA (2014)-1st Annual MEGSA Symposium, Riverside, CA (2014)-Materials Research Society (MRS) Spring Meeting and Exhibit, Phoenix, AZ (2016)-Materials Research Society (MRS) Spring Meeting and Exhibit, Phoenix, AZ (2017)-The 18th Annual UC Systemwide Bioengineering Symposium, Los Angeles, CA (2017) Show less -Teaching assistant for 11 courses within the Bioengineering and Mechanical Engineering Departments in subjects as biochemistry, circulation physiology, statics, and engineering graphics and design-Prepared course material for weekly discussions and laboratory sections-Graded homework, exams, and projects-Proctored midterm and final examinations-Created documentation binders for the Accreditation Board for Engineering and Technology (ABET)Courses Taught:-Quantitative Biochemistry (BIEN 101) - Fall Quarter, 2014-Circulation Physiology (BIEN 105) - Winter Quarter, 2014-Engineering Graphics and Design (ME 009) - Spring Quarter, 2015-Experimental Techniques (ME 170B) - Fall Quarter, 2015-Statics (ME 010) - Winter Quarter, 2016-Engineering Graphics and Design (ME 009) - Spring Quarter, 2016-Linear Systems and Controls (ME 120) - Summer Session, 2016-Experimental Techniques (ME 170B) - Fall Quarter, 2016-Mechanical Engineering Design (ME 175B) - Winter Quarter, 2017-Engineering Graphics and Design (ME 009) - Spring Quarter, 2017-Introduction to Engineering Computation (ME 018) - Fall Quarter, 2017 Show less

  • Graduate Student Researcher

    Aug 2012 - Aug 2018

  • Teaching Assistant

    Sept 2014 - Dec 2017
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  Stryker

  Jan 2019 - now

  • Senior Staff Engineer, Advanced Technologies & Innovations

    Oct 2023 - now

  • Senior Staff Preclinical Researcher

    May 2022 - Oct 2023

  • Staff Preclinical Researcher

    Nov 2020 - May 2022

  • Senior Preclinical Researcher

    Jan 2019 - Nov 2020