Matilde Maria Coppi

Experience

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  Dept. of Life Sciences – University of Siena,

  Apr 2016 - Apr 2017

  Intern, Dept. of Life Sciences – University of Siena

  Bachelor’s degree research projectVerify growth, development and the metabolic response of the pollen tube lacking nutrients in thegrowth medium. The following analyses have been carried out: germination in glycerol-rich growthmedium; ATP/ADP analysis using HPLC; observation of ROS and pH variations; pectinsdistribution analysis; immunologic analysis of phosphoproteins from cytosol, membrane andcellular wall.

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  Dept. of Molecular Biotechnologies – University of Siena

  Sept 2018 - Dec 2019

  Intern, Dept. of Molecular Biotechnologies – University of Siena

  Master’s degree research projectAnalyze the effect of NT4 peptide on cancer cell adhesion and motility of different cancer celllines; analyze the modifications NT4 can induce in the organization of the actin cytoskeleton andinvestigate the expression of proteins involved in signaling pathways that regulate actin dynamics.

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  Liceo Scientifico Galileo Galilei - Siena

  Oct 2021 - Oct 2021

  High School Teacher

  Taught Biology, Chemistry, and General Science to students from the first to the fifth year of an Italian scientific high school (Liceo Scientifico). Designed and delivered lessons, prepared assessments, and supported students in developing a strong scientific foundation.

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  Ludwig Cancer Research

  Apr 2022 - now

  Doctoral Researcher

  - Developed a B cell-based vaccine platform for the prevention of solid tumors, contributing to novel strategies in cancer immunotherapy. - Designed and optimized experimental workflows, including B cell culture, immune assays (e.g., ELISpot, FACS), and data analysis, ensuring reproducibility and robustness.- Investigated the role of B cells in tumor immunity, leveraging their potential for vaccine development.- Presented findings at scientific conferences and contributed to manuscript preparation for peer-reviewed publications. Show less