Enzo Morro

Education

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  Lycée International de Ferney-Voltaire

  -

  Baccalauréat Sciences
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  Ecole polytechnique fédérale de Lausanne

  2012 - 2013

  Mechanical Engineering
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  Université Claude Bernard Lyon 1

  2013 - 2015

  Pre-Medicine/Pre-Medical Studies
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  Université Claude Bernard Lyon 1

  2015 - 2017

  Bachelor's degree Biochemistry and Molecular Biology
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  Université Claude Bernard Lyon 1

  2017 - 2019

  Master Biochemistry and Molecular Biology - Specialization in functional and structural biology
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  EPFL

  2020 - 2024

  Doctor of Philosophy - PhD Biotechnology and Bioengineering

  "Exploring the therapeutic potential of Huntingtin native state stabilization through targeting its interacting partners"- Optimized the purification process and conducted biophysical characterization of a recombinant 40kDa huntingtin-associated protein- Assessed the proteolysis and aggregation dynamics of HTT in vitro and in cellulo using techniques such as negative-stained TEM, LC-MS/MS, DLS, solubility assays and confocal microscopy- Performed in silico mutagenesis… Show more "Exploring the therapeutic potential of Huntingtin native state stabilization through targeting its interacting partners"- Optimized the purification process and conducted biophysical characterization of a recombinant 40kDa huntingtin-associated protein- Assessed the proteolysis and aggregation dynamics of HTT in vitro and in cellulo using techniques such as negative-stained TEM, LC-MS/MS, DLS, solubility assays and confocal microscopy- Performed in silico mutagenesis and experimental binding characterization of mutant proteins in stable cell lines, employing site-directed mutagenesis and co-IP- Teaching assistant and supervised BSc and MSc projects Show less