Sanghamitra Sen

Experience

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  Dainippon Ink & Chemicals

  Jul 2002 - Jul 2005

  Development Chemist

  • Worked on the development of eco-friendly inks for various printing processes, and on a wide range of porous & non-porous flexible substrates and their corresponding surface modification. • Led the laboratory development of customized products, color matching, scale-up, and physical testing of the raw ink and printed materials.• Helped to coordinate field trials of new ink formulations and in the commercialization process.

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  Virginia Tech

  Aug 2005 - Apr 2011

  Dissertation title: Perfluoroarylated Cyclopentadienones: Synthesis, Characterizationand Polymerization Synthesis of highly fluorinated bis-cyclopentadienone monomer:o Designed and synthesized fluorine rich cyclopentadiene monomer precursor through aromatic nucleophilic substitution reaction. o Studied a new solvent system for fluorine-based aromatic nucleophilic substitution reaction. o Developed a novel catalytic oxidation method for fluorinated cyclopentadiene system. o Characterized the fluorinated monomer through 1H, 19F NMR, FT-IR spectroscopy, mass spectrometry and x-ray crystallography. Synthesis of novel diyne monomer: o Synthesized diyne monomer through metal catalyzed sonogashira coupling reaction.o Characterized the diyene monomer through 1H and 13C NMR spectroscopy, mass spectrometry and x-ray crystallography. Diels-Alder polymerization of perfluoroarylated cyclopentadienone and diyne:o Studied different conditions of the Diels-Alder polymerization reaction. Examined the effect of solvent and temperature on the molecular weight of the polymer. o Characterized the polymer through 1H and 19F spectroscopy, SEC, TGA and DSC.  Synthesis of fluorinated self-healing polymer:o Synthesized fluorinated cyclopentadiene monomer system through nucleophilic substitution reaction.o Synthesized bis-maleimide monomer system by condensation reaction of 4,4’-diaminodiphenyl ether and maleic anhydride. o Characterized the monomers through 1H, 13C and 19F NMR spectroscopy and X-ray crystallography. o Synthesized the self-healing polymer through the Diels-Alder reaction of fluorinated cyclopentadiene and bis-maleimide.o Characterized the polymer through 1H and 19F NMR spectroscopy, SEC, TGA and DSC. o Studied the thermal reversibility of the polymer through Flash Vacuum Thermolysis. Show less Courses Taught. General Chemistry lab (Chem 1045 and Chem 1046) as a lab instructor, General Chemistry Lecture (Chem 1035and Chem 1036) as a recitation instructor. Teaching responsibilities:• Conduct undergraduate labs (72 students per semester). Pre-lab lectures, pre-running of the experiments, demonstrating the techniques, assisting students in the laboratory routines and grading laboratory reports. • Conducting undergraduate recitations. Helping the students to understand the class lectures, assisting the students with their home works and projects. • Other responsibilities. Helping the professors to set up the exams, assisting them in the examination room and grading. Show less

  • Ph. D. in organic polymer chemistry

    May 2008 - Apr 2011

  • Graduate Teaching Assistant

    Aug 2005 - Apr 2011

  • M.S. in Chemistry

    Aug 2005 - Apr 2008
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  North Carolina State University

  Jul 2011 - Nov 2013

  Postdoctoral Associate

   Chemical modification and characterization of soft wood kraft lignin to create bio-based thermoplastic materials with high temperature stability: (Project funded by Solvay Specialty Chemicals) • Studied the thermal stability of soft wood kraft lignin. • Developed a novel green synthetic route to control the reactivity of soft wood kraft lignin. • Developed a soft wood kraft lignin-based elevated temperature stable poly(arylene sulfone) system. • Characterized chemically modified kraft lignin via 1H and 13C NMR, and FT-IR spectroscopy, SEC, TGA, and DSC.  Towards the development of soft wood kraft lignin-based carbon fibers: (Project funded by Domtar Corporation) • Fractionated soft wood kraft lignin through dissolution in acetone to obtain a low molecular weight fraction. • Propargylated acetone soluble soft wood kraft lignin through nucleophilic substitution reaction. • Developed a novel procedure to generated high molecular weight bio-polymer by heating the propargylated lignin at elevated temperature. • Performed the thermal polymerization of propargylated lignin in twin screw extruder for the development of lignin based carbon fibers. • Developed a novel lignin-based high molecular weight polymer via oxidative polymerization of propargylated lignin through Glaser Hay coupling. • Characterized the chemically modified lignin through 1H, 13C NMR, FT-IR spectroscopy, SEC, TGA, DSC. Dissolution of cellulose in in molten inorganic salt hydrates: • Studied the dissolution mechanism of cellulose in zinc chloride hydrate. • Designed and developed a turbidimetric titration instrument to study the dissolution mechanism of cellulose in aqueous solution of zinc chloride hydrate. • Characterized the regenerated cellulose by SEC and TGA. Show less

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  The University of Akron

  Oct 2014 - May 2018

  • Managed a highly motivated and dynamic chemical laboratory consisting of six graduate and two undergraduate students. Supervised the graduate and undergraduate students with laboratory related duties. • Supervised laboratory purchasing and equipment maintenance, which includes managing the internal budget (about 200K), as well as having an understanding of grant spending for these items.• Proficient in PeopleSoft Financial Management process. • Mentored 3 graduate and 1 undergraduate students.• Served as a safety officer • Organized laboratory open house and other fund raising events. Show less  Designing, synthesis and characterized vitamin targeted poly(ethylene glycol)-based (PEG) theranostics for breast cancer diagnosis and therapy: • Synthesized folate targeted PEG-based fluorescein marked diagnostic agents for breast cancer diagnosis. • Conducted Candida antarctica lipase B (CALB) enzyme catalyzed functionalizations of PEG and folic acid. • Synthesized folate targeted PEG-based Doxorubicin marked theranostics for breast cancer diagnosis and therapy. • Characterized the diagnostic and theranostics agents via 1H and 13C NMR spectroscopy, mass spectrometry and SEC. • Performed cell culture studies in collaboration with Cleveland Clinic. Developed and characterized biodegradable polyisobutylene (PIB) for slow release drug delivery application: • Synthesized low molecular weight PIB through carbocationic polymerization. • Synthesized thiol functionalized PIB macrmonomer through UV mediated thiol-ene click reaction and CALB enzyme catalyzed transesterification reaction. • Synthesized PIB-Based polydisulfides through oxidative polymerization reaction of thiol functionalized PIB. • Characterized PIB macromonomer and PIB-based polydisulfides via 1H, 13C , and 2D HMBC NMR spectroscopy, Raman spectroscopy and SEC. • Examined thermal stability of the macromonomer and the polymer via TGA and glass transition temperature via DSC. • Studied the biodegradability of the polymer in vitro through treatment with reducing agent Dithiothreitol. Show less

  • Research Professor

    Mar 2017 - May 2018

  • Lab Manager

    Mar 2017 - May 2018

  • Postdoctoral Research Fellow

    Oct 2014 - May 2018
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  Evolved By Nature

  May 2018 - Jul 2019

  Scientist
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  STAHLS'​

  Aug 2019 - Aug 2021

  Polymer Chemist

  • Led the development of primer formulations for inkjet printing on polyester film for Direct to Film (DTF) printing technology.• Developed a universal hot-melt adhesive formulation across various polymer-based (acrylic, PVC and polyurethane) transfer printing systems.• Designed experimental plans and executed experiments at lab scale independently as well as in collaboration with teams. Supervised production of new material.

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  Align Technology

  Oct 2021 - now

  Senior Scientist