Megan Rice

Experience

• 

  SUNY Potsdam

  Aug 2006 - May 2008

  Laboratory Technician

  Prepared laboratory materials and equipment for classroom experiments. This included but was not limited to: making media, cleaning and sterilizing equipment, preparing solutions, maintaining cultures, etc.

• 

  University of Massachusetts Amherst

  Aug 2011 - May 2013

  Research Assistant

  Identified the key proteins that comprise unique organelles known as bacterial microcompartments found in the organism C. phytofermentans and mapped the pathway by which C. phytofermentans metabolizes the monosaccharide, D-Arabinose.

• 

  Array BioPharma Inc.

  Dec 2013 - Jul 2015

  R&D Associate I

  Structural Biology- Characterization of kinase-small molecule interactions. Expression by way of mammalian, insect and bacterial cell culture combined with protein purification, biochemical assessment, crystallography and structural analysis.

• 

  MedImmune

  Oct 2015 - Jun 2019

  Antibody Discovery & Protein Engineering- Antibody-drug conjugate (ADC) engineering and characterization by way of novel non-canonical amino acid application. Antibody Discovery & Protein Engineering- Application of non-natural amino acid technology to the discovery and development of cancer-targeting biologics.

  • Associate Scientist I

    Jun 2017 - Jun 2019

  • R&D Associate II

    Oct 2015 - May 2017
• 

  AstraZeneca

  Jun 2019 - now

  Biologics Engineering co-lead; responsible for successful leadership of pre-clinical ADC projects through AstraZeneca's oncology portfolio. This includes, but is not limited to, target selection, lead generation and lead optimization. Specialization: non-canonical amino acids for engineering site-specific antibody-drug conjugates Engineering antibody conjugates with an assortment of payloads by exploiting the efficiency and stability of non-natural amino acids. MedImmune/AstraZeneca company merger - Antibody Discovery & Protein Engineering- Antibody-drug conjugate (ADC) engineering and characterization by way of novel non-canonical amino acid application.

  • Senior Scientist

    Jul 2022 - now

  • Scientist

    Jul 2021 - Jul 2022

  • Associate Scientist I

    Jun 2019 - Jul 2021