Bram Koster

Experience

• 

  TVIPS GmbH

  Sept 1989 - Aug 1991

  Project manager microscopy automation

  Automation of electron microscopy. Image processing. Digital image recording.

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  UCSF Medical Center

  Sept 1991 - Aug 1993

  Postdoctoral Research Fellow

  Postdoctoral fellow in the Molecular Structure group of David Agard. Development and application of specialized electron microscopy techniques: 3D Electron tomography, Automation,TEM, Stained sections, Chromatin.

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  Max-Planck-Institute for Biochemistry, Martinsried, Germany

  Sept 1993 - Dec 1997

  Postdoctoral Research Fellow

  Postdoctoral fellow in the Molecular Structural Biology group of Wolfgang Baumeister. Development and application of specialized electron microscopy techniques: 3D Cryo electron tomography, Automation, Cryo-TEM, Macromolecular structures, Proteasomes.

• 

  Utrecht University

  Jan 1998 - Dec 2005

  Associate professor (UHD) in the group of Arie Verkleij. Acquisition of funding. Supervision of PhD students and technicians. Electron tomography. Development and application of specialized electron microscopy techniques: 3D Electron Microscopy, Electron Tomography, STEM, Energy-filtering, Gold-Labeling, Stained sections.

  • Staff Scientist Electron Microscopy

    Jan 1998 - Dec 2005

  • Research Fellow of the Royal Academy of Sciences (KNAW)

    Jan 1998 - Dec 2002
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  Leiden University Medical Center

  Jan 2006 - now

  Full professor Electron Microscopy. Working on fundamental research topics as well as on advanced applications of light and electron microscopy techniques. Techniques and methods include cryo electron tomography, cryo electron microscopy, serial block face SEM and multimodal, multi-scale imaging. Interested in automation of microscopy workflows, ranging from instrumentation control to annotation of cell morphologies, using conventional image processing approaches as well as artificial intelligence and machine learning. Show less Management of the research group, defining long-term scientific research goals, acquisition of funding, collaborations with other scientific and industrial research groups, effective and efficient embedding of the microscopy research group within the Leiden University Medical Center to contribute to its overall mission. Management of the Section Light and Electron Microscopy, defining long-term research lines and positioning the Section with the overall organization of the Leiden University Medical Center. Roles in various in-house, national and international committees and organizations. Show less

  • Professor Electron Microscopy, Faculty of Medicine

    Jan 2007 - now

  • Head Section Electron Microscopy

    Jan 2006 - May 2022
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  Netherlands Center for Electron Nanoscopy (NeCEN)

  Sept 2015 - Oct 2018

  Scientific Director

  NeCEN is the Netherlands Center of Electron Nanoscopy. NeCEN is the open access facility for cryo-TEM in The Netherlands. Management of the center, defining long-term scientific research goals, acquisition of funding, realizing collaborations with international scientific and industrial partners, effective and efficient embedding of the NeCEN within the Dutch and European electron microscopy community.

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  Leiden University

  Sept 2015 - now

  Professor Nanobioimaging, Faculty of Science

  Professor Nanobioimaging at the Faculty of Science within the Institute of Biology. Development and application of cryo electron microscopy methods and techniques.

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  Centro Nacional de Biotecnología (CNB-CSIC)

  Oct 2022 - Oct 2022

  Visiting Scientist

  Cryo tomography workflows with Scipion

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  UCSF SCHOOL OF MEDICINE

  Mar 2023 - May 2023

  Sabbatical

  Collaboration on cryo tomography structure determination methods in the Macromolecular Structure Group