Priya Sharma

Education

• 

  Delhi University

  2011 - 2014

  Bachelor's degree Zoology/Animal Biology

  Worked on internship project-"Biomarkers of heat stress and acclimation".

• 

  Indian Institute of Science Education and Research (IISER), Mohali

  2014 - 2017

  Master of Science - MS Biology/Biological Sciences, General

  Activities and Societies: Biology Discussion Forum(BDF) MS Thesis project-"To study wnt signalling in context of zebrafish caudal fin regeneration".ABSTRACT-Wnt signaling is known to be involved in retina regeneration but its importance in fin regeneration has not been studied yet.LiCl is a positive regulator of Wnt signaling pathway by inhibiting GSK3β.So, we studied the effect of LiCl on zebrafish caudal fin regeneration and we found that LiCl acts a positive regulator of caudal fin regeneration by upregulating Wnt signaling pathway as… Show more MS Thesis project-"To study wnt signalling in context of zebrafish caudal fin regeneration".ABSTRACT-Wnt signaling is known to be involved in retina regeneration but its importance in fin regeneration has not been studied yet.LiCl is a positive regulator of Wnt signaling pathway by inhibiting GSK3β.So, we studied the effect of LiCl on zebrafish caudal fin regeneration and we found that LiCl acts a positive regulator of caudal fin regeneration by upregulating Wnt signaling pathway as blastema regeneration has increased from 125µM to 500µM.Along with this, we studied the effect of tumour suppressor gene Ptenb inhibitor and EDTA on fin regeneration and we found that both of these downregulates fin regeneration whereas HDACs inhibitor, LiCl and CaCl2 upregulates fin regeneration and we studied the effect of Lithium ions on embryos which revealed that embryos showed delayed hatching at 8dpf in the presence of Li ions as compared to the control as Lithium upregulates Wnt signaling. Show less