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Narasimha Rao Uda

Narasimha Rao Uda

INTERNSHIP (Lactase enzyme as drug supplement)

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location of Narasimha Rao UdaGeneva, Geneva, Switzerland

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  • Timeline

  • About me

    Maitre-Assistant (Senior Research Associate) at University of Geneva.

  • Education

    • University of Basel

      2009 - 2013
      Doctor of Philosophy (PhD) Biochemistry and Molecular Biology

      Responsibilities & Achievements: Key role in negotiations & decision making in establishing a new laboratory; Lab management; Project management; Internal Biosafety Officer; Organization of scientific meetings; Teaching laboratory courses; Supervising master students & technicians; Networking & establishing collaborations; Writing grant applications. Assay development; Writing manuscripts & publishing in peer reviewed journals.Project: Understanding the molecular mechanisms behind… Show more Responsibilities & Achievements: Key role in negotiations & decision making in establishing a new laboratory; Lab management; Project management; Internal Biosafety Officer; Organization of scientific meetings; Teaching laboratory courses; Supervising master students & technicians; Networking & establishing collaborations; Writing grant applications. Assay development; Writing manuscripts & publishing in peer reviewed journals.Project: Understanding the molecular mechanisms behind evolution of the new enzymatic activities through directed evolution, in order to design novel antibiotics for rapidly evolving multi-drug resistant bacteria.Skills: Molecular cloning & plasmid construction; Protein engineering & directed evolution; Protein expression in bacteria & purification (FPLC); Screening small molecule libraries for antimicrobial activity; Enzymology; Molecular biology & Protein modelling. Show less

    • Sri Venkateswara University

      1998 - 2001
      Bachelor of Science (B.Sc.) Microbiology & Chemistry

    • Bangalore University

      2001 - 2003
      Master of Science (M.Sc.) Biotechnology

    • University of Skövde

      2007 - 2008
      Master of Science (M.Sc.) Molecularbiology

  • Experience

    • Anglo-French Drugs & Industries Ltd.

      Jun 2002 - Nov 2002
      INTERNSHIP (Lactase enzyme as drug supplement)

    • Indo-American Hybrid Seeds Pvt. Ltd.

      Dec 2002 - May 2003
      INTERNSHIP (Plant genetic engineering & Tissue culture)

    • Sri Bhagawan Mahaveer Jain College

      Jun 2003 - Jan 2006
      Lecturer (Cell biology, Biochemistry, Microbiology & Genetics)

    • Roskilde University

      Apr 2006 - Jan 2007
      INTERNSHIP (Cell & Molecularbiology)

    • Karolinska Institutet

      May 2008 - Mar 2009
      Master's thesis (Drug discovery in Cancer & Inflammation) @ Actar AB. & Karolinska Institute.

      Identification of key residues determining interspecies differences in inhibitor binding of Microsomal Prostaglandin E Synthase 1

    • University Hospital Basel

      Jul 2013 - Dec 2015
      Postdoctoral Fellow (Project Manager) @ Agenusbio (4-Antibody AG.) & University Hospital Basel.

      Responsibilities & Achievements: Cost effective budgeting and project management; Assay development; Bridging academic & industrial partner (4-Antibody AG); Organization of scientific meetings; Writing & publishing research articles; Writing interim reports & grant Applications.Project: Understanding tumor micro-environment (Hypoxia & pH homeostasis) and targeting cancer-specific markers in pH homeostasis: Carbonic anhydrase 9 & 12.Skills: Antibody-library construction; Antibody expression in mammalian cells & purification; 3D cell culture models (Spheroids); Hypoxia; Culturing cell lines, primary cells & tumor-explants; CRISPR Cas9 technology; Flow-cytometry; RT-qPCR; Fluorescence microscopy; Cellular functional & Immunological assays and high-throughput assay development. Show less

    • University of Geneva

      Jan 2016 - now

      Responsibilities & Achievements: Project management; Organization of Scientific Meetings; Teaching (Seminars & Laboratory Courses); Supervising Master students, Establishing new methods & in vitro assays; Networking & Establishing Collaborations; Writing research articles & grant Applications.Project: Understanding the metabolic reprogramming of cancer cells in cancer progression & immune suppression. Targeting cancer specific markers in Lipid metabolism to enhance the efficacy of cancer immune response & immunotherapy.Skills: CRISPR Cas9 technology; Flow-cytometry; RT-qPCR; Fluorescence microscopy; Cellular functional & Immunological assays; Culturing Cell lines & primary cells; In vivo experiments in mouse. Show less

      • Maitre-Assistant (Senior Research Associate)

        Jan 2018 - now

      • Postdoctoral Fellow (Project Manager) @ University of Fribourg & University of Geneva.

        Jan 2016 - Dec 2017

  • Licenses & Certifications

    • LTK module 1

      FEDERATION OF EUROPEAN LABORATORY ANIMAL SCIENCE ASSOCIATIONS (FELASA)
      Aug 2013

  • Honors & Awards

    • Awarded to Narasimha Rao Uda
      SCNAT/SCS Chemistry travel award-2012 Swiss Chemical Society (SCS) Aug 2012 2nd Symposium on Protein Engineering for Biocatalysis, 29th to 31st August 2012, Institute of Biochemistry, Greifswald University, Greifswald, Germany.
    • Awarded to Narasimha Rao Uda
      Travel bursary Biochemical Society, UK. Jan 2012 Annual Symposium 'Frontiers in biological catalysis', 10th to 12th January 2012, Robinson College, Cambridge, UK.
    • Awarded to Narasimha Rao Uda
      Travel grant for the workshop COST Action TD0905 Apr 2011 Scientific workshop on Epigenetics, 29th to 30th April 2011, MEDILS Institute, Split, Croatia.
    • Awarded to Narasimha Rao Uda
      Travel grant for the conference COST Action CM0902 Mar 2010 Molecular machineries for ion translocation across biomembranes, 18th to 20th March 2010, Hotel AmRosenberg, Hofheim am Taunus, Frankfurt, Germany.
    • Awarded to Narasimha Rao Uda
      International Student Travel award SAS AB. (Scandinavian Airlines) and Danske Bank, Denmark. Jan 2006

  • Volunteer Experience

    • Reviewer: Cancer and Oncology Research

      Issued by Horizon Research Publishing Co.,Ltd. on Nov 2014
      Horizon Research Publishing Co.,Ltd.Associated with Narasimha Rao Uda

    • Editorial Manager: (1) Cogent Medicine and (2) Cogent Biology

      Issued by Taylor & Francis Group on Dec 2016
      Taylor & Francis GroupAssociated with Narasimha Rao Uda

    • Reviewer for Four Journals

      Issued by Dove Press on Oct 2016
      Dove PressAssociated with Narasimha Rao Uda

    • Reviewer: Int’l J. of Med. Sci. & Clinical Invention

      Issued by Valley International Journals on May 2016
      Valley International JournalsAssociated with Narasimha Rao Uda

    • Reviewer: (1) International Journal of Biology & (2) Cancer & Clinical Oncology.

      Issued by Canadian Center for Science & Education on Nov 2016
      Canadian Center for Science & EducationAssociated with Narasimha Rao Uda