Raffaele Sembiante

Experience

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  Institute of Environmental Assessment and Water Research (IDAEA-CSIC)

  Mar 2020 - May 2020

  Environmental Toxicological Control Internship

  Conduction of acute toxicity tests on Daphnia Magna cultures according to UNI EN ISO 6341:2012 method.Experience in the preparation of stock solutions, culture media, use of autoclave, interpretation of results and management of documentation.

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  Università degli Studi di Napoli Federico II

  Oct 2020 - Oct 2021

  Drug delivery internship

  Development of biodegradable PLGA-based nanoparticles for the delivery of 5-Fluorouracil for combined cancer therapy.Experience in quality control tests for tablets (disintegration tests according to Pharmacopoeia). Experience in analytical techniques for the qualitative-quantitative evaluation of active principal ingredients (UV/Vis spectroscopy, spectrofluorimetry, HPLC)Experience in colloid characterization techniques (PCS, zeta potential)Experience in validation of analytical methods, consultation of databases and use of software for laboratory data processing. Show less

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  Thermo Fisher Scientific

  Jan 2022 - now

  Review and approval of analysis for commercial batch release by chemical QC department. Ensure that each task has been performed in accordance with GMP and ensure Data Integrity.Report any non-compliance with protocols, methods and SOPs.Evaluation of OOS, OOT and stability behaviour in stability studies.Ensure compliance with USP, EP, JP requirements.Experience in reviewing analyses such as:-physical parts, detection of contaminants -HPLC assay for dosing, identification and purity (Empower3)-Karl Fisher-analysis by UV-vis spectrophotometer-analysis by IR spectrophotometer Show less

  • Process & Cleaning Validation Specialist

    Nov 2023 - now

  • QC Operations- Chemical Lab Reviewer - Commercial

    Jun 2022 - Nov 2023

  • QC Data Integrity Reviewer

    Jan 2022 - May 2022