Experience

• 

  University of virginia

  Oct 2015 - Jul 2016

  Undergraduate research assistant- agaisse laboratory

  Worked on vector cloning project involving Shigella flexneri in Dr. Hervé Agaisse's Lab at UVA• Ligated fluorescent protein strands into E. coli vectors and inserted them into Shigella for better live imaging • Performed PCR, prepared cell cultures, ran DNA gels, and analyzed DNA sequences using BLAST• Collected data will be used to develop better live imaging techniques to study bacterial movement

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  University of virginia

  Jan 2017 - May 2018

  Implemented a nuclear morphometry algorithm in Dr. Gustavo Rohde's Lab at UVA• Helped implement a pipeline in MATLAB that analyzed histology images to identify cell nuclei and perform classification on segmented samples• Analyzed a pancreatic cell data set in collaboration with pediatric physicians• Developed a segmentation GUI to allow doctors to efficiently select cell nuclei for analysis• Trained machine learning models to perform binary classification on feature vectors of cell nuclei• Improved nuclear segmentation method to automate cell identification and transformation into feature vectors.• Utilized algorithm on pancreatic histology images to quantify differences in samples pre-injury and post-injury. Show less

  • Computational BME - Teaching Fellow

    Jan 2018 - May 2018

  • Undergraduate Researcher - Imaging & Data Science Lab

    Jan 2017 - May 2018
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  Virginia commonwealth university - college of engineering

  Aug 2018 - Jul 2019

  Graduate student researcher - computational physiology lab

  Implementing an Epithelial Mesenchymal Transition (EMT) model in Dr. Seth H. Weinberg's Lab at VCU• Expanding single cell simulations into multiscale systems• Introducing fibronectin interactions into the existing network• Integrating differential equation chemical model with mechanical model to develop a fully representative model of EMTDeveloping an image processing pipeline for EMT fluorescence images• Performing feature extraction and reduction analysis to develop component data of fluorescence images• Using cluster analysis to group data into distinguishable epithelial and mesenchymal categories Show less

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  The ohio state university

  Aug 2019 - Aug 2022

  Graduate researcher assistant- computational physiology lab

  Implemented a cancer cell simulation model in Dr. Seth H. Weinberg's Lab at OSU• Integrated biochemical signaling model with mechanical framework to develop a hybrid mechanochemical signaling model of Epithelial Mesenchymal Transition (EMT).• Investigated tissue conditions in the presence/absence of growth factor.• Performed in silico scratch tests experiments to observe phenotypic effects on cell velocity and wound closure.Developed an image processing pipeline for distinguishing EMT in immunofluorescence images• Performed feature extraction to develop data of immunofluorescence images• Designed a phenotype scoring method to quantify the progression from the epithelial to mesenchymal phenotype.Investigated tissue dynamics in cancer• Developed a multicellular model to analyze the cellular and extracellular matrix dynamics in premetastatic niche involving stromal and tumor cells in colorectal cancer.Presented at: Biophysical Society (BPS) Annual Meeting 2019, 2020, 2021, 2022, Biology And Medicine through Mathematics (BAMM) 2019, Biomedical Engineering Society (BMES) Annual Conference 2019, Engineering in Healthcare: Industry and Research Symposium (EHIRS) 2021, 2022, Graduate Hayes Research Forum 2021, TEMTIA 2021 Show less

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  Johnson & johnson innovative medicine

  Aug 2022 - Aug 2024

  Postdoctoral fellow