Experience

• 

  Ranbaxy research laboratories ltd

  Sept 2002 - Jan 2004

  Research scientist

  Synthesis and designing of complex organic molecules, with activities of Medicinal interest.

• 

  Università di siena - career service

  Feb 2004 - Jul 2006

  Postdoctoral research fellow

  Involved in the development of new synthetic design strategies encompassing hybrid drugs and identification of novel chemically and metabolically stable small molecules for Antimalarial Chemotherapy & Hepatitis C Virus infection.

• 

  Eurofins advinus

  Aug 2006 - Oct 2009

  Group leader

  • Lead a discovery collaborative program with Merck on a novel anti-hypertensive target. o The program involved establishing proof of concept starting in vitro target validation to in vivo target engagement and eventually identifying lead molecules suitable for carrying pre-clinical studies• Integral part of the in-house anti-diabetic discovery program which resulted in a Phase-2 molecule.• Strategic oversight and management of group of scientists towards rational design of NCE’s and channeling their synthetic skills towards synthesis, developing structure-activity and structure- property relationships.• Promoting and coordinating effective interactions with interdisciplinary team members (biology, DMPK, pharmacology, toxicology, process development). Show less

• 

  Lupin

  Oct 2009 - Sept 2017

  Assistant director

  • Lead medicinal chemistry efforts in oncology programs catering to both novel and fast follow up targets • Inventor in one of first-in-class, novel oncology target (MALT1) which resulted in identification of clinical candidate LND700110 which got out licensed to AbbVie for further development across a range of hematological cancers thereby generating upfront revenue of US$30 million for LupinThe three facets of my job profile in the role of being a Project Leader involved owning responsibilities in the following domains  Scientific Leadership o Literature thoroughness in terms of being updated on current science, competitive intelligence relevant to target & therapeutic areao Thorough IP analysis to enable positioning of chemistry strategy taking care of assessment of novelty to build non-obviousness & timely filing of applicationso Laying down chemistry strategies while facilitating the team members to timely address the chemistry trouble shooting Strategic Leadershipo Designing patentable, biologically active NCEs following two pronged approach- advanced chemical approach and/or structure based drug design gathering insights from CADDo Speed up the Medchem iterative cycle by timely optimizing the chemical series for balancing the targeted biological activities and physicochemical propertieso Preparing crisp Medchem presentations while presenting to senior leadership team & overseas external chemistry consultants via webex, teleconferenceo Meeting project timelines while anticipating potential delays early Mentorshipo Played the role of being a mentor to the budding team members towards identifying their learning needs and help them acquire the necessary skill sets, both professional and personal to enable them meet their individual development plans for them to grow further Show less

• 

  Pi industries ltd

  Dec 2017 - Dec 2021

  • Deputy General Manager (Group Lead)

    Apr 2020 - Dec 2021

  • Senior Team Leader

    Dec 2017 - Apr 2020
• 

  Syngene international limited

  Dec 2021 - now

  Senior lead investigator