Socrates Radhakrishnan

Socrates Radhakrishnan

Junior Research Fellow

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location of Socrates RadhakrishnanCoimbatore, Tamil Nadu, India

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  • Timeline

  • About me

    Student at Anna University

  • Education

    • Anna University

      2012 - 2018
      Doctor of Philosophy - PhD Biotechnology, Biomaterials, Awarded

      Thesis title: "Biomimetic fabrication of a native fibrillar collagen composite for bone tissue engineering"Silver nanonoparticles were synthesized and synthesized silver nanoparticles were incorporated fibrillar collagen, chitosan and alginate for fabrication of composite scaffold. Composites has shown layered fibrillar arrangement and antibacterial activity without compromising biocompatibility. During my research, i handled cross-linking reaction using as EDC/NHS and glutaraldehyde and… Show more Thesis title: "Biomimetic fabrication of a native fibrillar collagen composite for bone tissue engineering"Silver nanonoparticles were synthesized and synthesized silver nanoparticles were incorporated fibrillar collagen, chitosan and alginate for fabrication of composite scaffold. Composites has shown layered fibrillar arrangement and antibacterial activity without compromising biocompatibility. During my research, i handled cross-linking reaction using as EDC/NHS and glutaraldehyde and performed various charaterizations such as tensile strength measurement, UV-visible spectrophotometer, FTIR, CD, HR-TEM, DSC, TGA, SEM, DLS etc. I also got experience in microbiology experiments to estimate the antimicrobial activity of the scaffold. Show less

    • Educational Institution

      2009 - 2011
      Master of Technology - MTech Biotechnology First Class

      Courses studied: Microbiology and Molecular biology, Biochemical Engineering, Recombinant DNA Technology, Immunotechnology, Advanced Bioprocess Engineering, Bio pharmaceuticals, Environmental biotechnology, Industrial management and Bioethics, Cancer Biology, Separation process in biotechnology and Enzyme and protein engineering.

    • Shanmugha Arts, Science, Technology and Research Academy

      2005 - 2009
      Bachelor of Technology - BTech Biotechnology First Class

      Courses studied: Cell biology, Bio-organic chemistry, Bioprocess Technology, Microbiology, Analytical techniques in biotechnology, Process calculations, Molecular biology, Biochemistry, Genetics, Materials science and technology, Genetic engineering , Bioprocess engineering, Separation processes, Enzyme engineering, Downstream processing, Environmental biotechnology, Pharmaceutical technology, Bioethics and biosafety, Immunotechnology, Plant and animal biotechnology and Food… Show more Courses studied: Cell biology, Bio-organic chemistry, Bioprocess Technology, Microbiology, Analytical techniques in biotechnology, Process calculations, Molecular biology, Biochemistry, Genetics, Materials science and technology, Genetic engineering , Bioprocess engineering, Separation processes, Enzyme engineering, Downstream processing, Environmental biotechnology, Pharmaceutical technology, Bioethics and biosafety, Immunotechnology, Plant and animal biotechnology and Food biotechnology.Skills:• Microbiological culture techniques• Extraction and purification of DNA, RNA and plasmid• Extraction and purification of enzyme• Analytical techniques such as paper and thin layer chromatography• Handled Microscope, UV-visible spectrophotometer, Agarose electrophoresis, SDS-PAGE electrophoresis, Western blotting, ELISA, PCR and etc., Show less

  • Experience

    • CSIR - Central Leather Research Institute

      Nov 2011 - Jun 2013
      Junior Research Fellow

      I joined CLRI as Junior research fellow in the project entitled "Synthesis and physical characterization of hydroxyapatite based scaffolds". During this research, I got experienced in collagen type I extraction, silver nanoparticles synthesis and biomineralization. I fabricated silver nanoparticles incorporated biomineralized native fibrillar collagen composite by biomimetic method. I also got training in biocompatibility studies, sample preparation for SEM analysis, handling microtome and experienced in sample preparation for tissue embedding, cutting and slicing. I also published this research work as research article in peer reviewed journal. Show less

    • University of Duisburg-Essen

      Sept 2016 - Sept 2016
      DAAD Research exchange scholar

      I collaborated with Prof. Matthias Epple in a project which was funded by DST-DAAD. I visited Prof. Matthias Epple laboratory as an exchange student for carrying out research work under the project entitled "Development of biomimetic composite scaffolds for tissue regeneration and drug delivery". I fabricated antimicrobial collagen-based composite biomaterial using collagen, chitosan and silver nanoparticles by biomimetic techniques. I also got a training to characterize composites with various characterization techniques, i.e. SEM, EDX, XRD, DSC, TGA, and contact angle measurement. Further, i also published this research work in a joint research article with Prof. Matthias Epple group. Show less

    • Crystal Growth Centre, Anna University, Chennai-600020

      Dec 2016 - Nov 2018
      Research Associate
    • University of Montpellier

      Dec 2018 - Aug 2019
      CEFIPRA research exchange scholar and Post-doctoral research scholar

      I had associated with Dr. Mikhael Bechelany as a researcher from Crystal Growth Centre, Anna University, Chennai-25, through joint Indo-French collaborative IFCPAR/CEFIPRA project entitled “Biodegradable core shell electrospun mats and interconnected porous scaffolds for tunable anticancer drug delivery and tissue engineering application”. I got training in fabricating scaffolds using FDM based 3D printer and bioprinter. Under this project, i fabricated antimicrobial 3D scaffold using silver nanoparticles, polycaprolactone and calcium phosphate. Further, i also gained experience in characterizing the materials and handling microbial culture for analyzing antimicrobial activity. I also published this research findings in four scientific publications as one book chapter, one review article and two research articles. Show less

    • Ponni Symbiologicals

      Apr 2022 - now
      Junior Scientist
  • Licenses & Certifications

    • Workshop on "Techniques and applications of Transmission Electron Microscopy"

      Department of Electron Microscopy, Cancer Institute (WIA), Chennai
      Aug 2014
    • Certificate course in "Medicinal chemistry"

      Shanmugha Arts, Science, Technology & Reserch Academy (SASTRA), Thanjavur
      Jun 2007
    • Certificate course in "Technical communication skills"

      Shanmugha Arts, Science, Technology & Reserch Academy (SASTRA), Thanjavur
      Jun 2006
  • Volunteer Experience

    • Organizer

      Issued by Anna University Chennai on Feb 2015
      Anna University ChennaiAssociated with Socrates Radhakrishnan
    • Organizer

      Issued by Anna University on Dec 2017
      Anna UniversityAssociated with Socrates Radhakrishnan