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Jonathan Cimino

Jonathan Cimino

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location of Jonathan CiminoBrussels, Brussels Region, Belgium

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  • Timeline

  • About me

    Clinical Director Research H.U.B/Assoc. Prof. Dr

  • Education

    • Harvard Medical School

      2015 - 2015
      Internship Translational Research

    • Université de Liège

      2011 - 2012
      Cat C Animal Experiment Leader FELASA (Federation of Laboratory Animal Science Associations) Animal experiment

      Cat C Animal Experiment Leader FELASA (Federation of Laboratory Animal Science Associations)

    • Université de Liège

      2011 - 2015
      Ph.D. in Biomedical and Pharmaceutical Sciences Biomedical sciences-Cancer-Antiangiogenic therapy-Proteomic-Imaging mass spectrometry https://www.ulg.ac.be/cms/c_6702258/fr/jonathan-cimino

      Activities and Societies: https://www.ulg.ac.be/cms/c_6702258/fr/jonathan-cimino I provided a repertoire of significantly modulated genes, proteins and metabolites, some with yet unknown roles in tumor adaptation process notably involved in cancer cell aggressiveness after antiangiogenic treatment withdrawal by:- Characterized one major metabolic regulator of RTKI’s adaptation (FASN).- Overcome tumor adaptation to antiangiogenic drugs, using cell biology and “omics” profiling (Genomic, Proteomic and Metabolomic studies).- Examined metabolic effects… Show more I provided a repertoire of significantly modulated genes, proteins and metabolites, some with yet unknown roles in tumor adaptation process notably involved in cancer cell aggressiveness after antiangiogenic treatment withdrawal by:- Characterized one major metabolic regulator of RTKI’s adaptation (FASN).- Overcome tumor adaptation to antiangiogenic drugs, using cell biology and “omics” profiling (Genomic, Proteomic and Metabolomic studies).- Examined metabolic effects of the RTKIs during and after treatment withdrawal in various in vivo/in vitro models. Show less

    • Université de Liège

      2005 - 2009
      Bachelor's degree in Biomedical and Pharmaceutical Sciences Biomedical and Pharmaceutical Sciences

    • Université de Liège

      2009 - 2011
      Master in Biomedical and Pharmaceutical Sciences Biomedical and Pharmaceutical Sciences-Oncology research

      Dissertation: Imaging Mass spectrometry and quantitative proteomic analysis to decipher the differential angiogenic response of RTKI (sunitinib) treated breast adenocarcinoma cells before and after treatment withdrawal. Project - Development of various xenograft models - Performed Imaging mass spectrometry from xenograft by MALDI-TOF (protein) and MALDI-FTICR (lipid) - Performed quantitative proteomic by Synapt G1 HDMS (Electrospray Q-TOF) - Cell culture and… Show more Dissertation: Imaging Mass spectrometry and quantitative proteomic analysis to decipher the differential angiogenic response of RTKI (sunitinib) treated breast adenocarcinoma cells before and after treatment withdrawal. Project - Development of various xenograft models - Performed Imaging mass spectrometry from xenograft by MALDI-TOF (protein) and MALDI-FTICR (lipid) - Performed quantitative proteomic by Synapt G1 HDMS (Electrospray Q-TOF) - Cell culture and differentiation - Performed immunohistochemistry protocol Show less

  • Experience

    • Université de Liège

      Sept 2009 - Jan 2015

      I provided a repertoire of significantly modulated genes, proteins and metabolites, some with yet unknown roles in tumor adaptation process notably involved in cancer cell aggressiveness after antiangiogenic treatment withdrawal by:- Characterized one major metabolic regulator of RTKI’s adaptation (FASN).- Overcome tumor adaptation to antiangiogenic drugs, using cell biology and “omics” profiling (Genomic, Proteomic and Metabolomic studies).- Examined metabolic effects of the RTKIs during and after treatment withdrawal in various in vivo/in vitro models. Show less

      • Ph.D. in Biomedical and Pharmaceutical Sciences

        Jan 2011 - Jan 2015

      • Assistant position, Cell Culture, Mass Spectrometry and Proteomic

        Sept 2010 - Sept 2011

      • Assistant position, Molecular Biology, University of Liège

        Sept 2009 - Sept 2010

    • Harvard Medical School

      Jan 2015 - Jan 2015
      Harvard Medical School- Cancer Imaging Translational Research

      Foundation Camille Hela excellence prize (Article in “Cell Metabolism”)Harvard Medical School & Brigham and Women's HospitalOperational Training in Cancer-Imaging Mass spectrometry for clinical trialsPilot Study to Evaluate Image-guided Breast Cancer Conserving Surgery in the Advanced Multimodality Image Guided Operating Suite (AMIGO)Stage I & II Breast Carcinoma + Brain MetastasisSurgical decision-making: Collect real-time data during brain/breast tumor surgery in the Advanced Multimodality Image Guided Operating (AMIGO) by DESI and LESA Mass Spectrometry MethodDr. Calligaris D. and Pr. Agar N. Show less

    • GIGA - Université de Liège

      Aug 2015 - Jul 2016
      Researcher/Project Leader- Cancer Targeted Therapies for clinical studies

    • Artialis

      Mar 2016 - Nov 2017
      Clinical Project Leader

      Working together with Clinical Operation Director to ensure clinical operations linked to clinical project (all phases of clinical Research).

    • Luxembourg Institute of Health

      Oct 2017 - Dec 2020

      • Clinical Researcher & Coordinator

        Oct 2017 - Dec 2020

      • Biosafety and Safety CP (volunteer)

        Oct 2017 - Dec 2020

    • ECRIN (European Clinical Research Infrastructure Network)

      Jul 2019 - Dec 2020
      European correspondent for ECRIN (European Clinical research Infrastructure Network)

    • University of Liège

      Aug 2020 - now

      Teaching: "Translational research, from scientific protocol to clinical protocol" The lecture will present the different stages that influence the design of a clinical research protocol by emphasizing the link between fundamental research essential to any progress, and clinical research concerned with patients. The research question, regulatory requirements (GCP, ICH, GDPR) will be addressed. Examples from real studies will be presented and discussed.https://www.programmes.uliege.be/cocoon/20202021/formations/bref/MYECLI90.html Show less

      • Associate Professor

        Feb 2024 - now

      • Clinical Trial University Certificate (ULiège) referent/coordinator for Luxembourg

        Aug 2020 - now

      • Maître de Conférences/University Lecturer

        Aug 2020 - Feb 2024

    • Hôpitaux Robert Schuman

      Dec 2020 - Nov 2023
      Head of Clinical Research (Fondation Hôpitaux Robert Schuman)

    • University of Luxembourg

      Sept 2021 - now
      Adjunct Teaching Staff Member (DES General Medicine/Oncology/ Neurology)

    • Hôpital Universitaire de Bruxelles (H.U.B) - Academisch Ziekenhuis Brussel (H.U.B)

      Nov 2023 - now
      Clinical Director of Research

  • Licenses & Certifications

    • Certificate of GCP Training - Case based GCP - for experienced

      Jun 2018

    • Federation of European Laboratory Animal Science Associations (FELASA)

      Université de Liège (ULg)
      Oct 2012
      View certificate certificate

    • ISO 14155

      House GCP Training Courses
      Jan 2018

    • Training phase 1 clinical trial

      INSTITUT CLAUDIUS REGAUD
      Sept 2019

    • Training in Monitoring Clinical Trials in accordance with ICH-GCP Guidelines

      GCP Clinical Studies
      Mar 2016

  • Honors & Awards

    • Awarded to Jonathan Cimino
      Pierre Van Beirs award, 2015 Pierre Van Beirs award Nov 2015 Pierre Van Beirs award, 2015
    • Awarded to Jonathan Cimino
      Annick Griez award Anti-Cancer Center (ULg) 2015 Annick Griez award (Cancer research), Belgium 2015.
    • Awarded to Jonathan Cimino
      Best oral presentation prize, EDT-CANCER EDT-CANCER 2014 Best oral presentation prize, EDT-CANCER, Belgium 2014
    • Awarded to Jonathan Cimino
      Best poster prize, GIGA-CANCER-DAY GIGA-CANCER-DAY 2014 Best poster prize, GIGA-CANCER-DAY, Belgium 2014.
    • Awarded to Jonathan Cimino
      Foundation CAMILLE HELA award Foundation CAMILLE HELA 2014 Foundation CAMILLE HELA award for Research Travel to Harvard Medical School (USA), Belgium.
    • Awarded to Jonathan Cimino
      Foundation CENTRE ANTICANCEREUX fellowship Foundation CENTRE ANTICANCEREUX 2014 Foundation CENTRE ANTICANCEREUX fellowship for Research Travel to Harvard Medical School (USA), Belgium.
    • Awarded to Jonathan Cimino
      Foundation FONDS LEON FREDERICQ fellowship Foundation FONDS LEON FREDERICQ 2013 Foundation FONDS LEON FREDERICQ fellowship, Belgium 2013.
    • Awarded to Jonathan Cimino
      Foundation “Patrimoine of University of Liège” award University of liège 2013 Foundation “Patrimoine ULg” fellowship for Research Travel to American Society for Mass Spectrometry (ASMS), Minneapolis (USA), University of Liege, Belgium 2013.

  • Volunteer Experience

    • Member

      Issued by Rotary International
      Rotary InternationalAssociated with Jonathan Cimino