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Thomas Rix

Thomas Rix

Student Virologist

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location of Thomas RixLondon, England, United Kingdom

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  • Timeline

  • About me

    PhD student at Imperial College London, Bioinformatics and Data Science

  • Education

    • University of Surrey

      2016 - 2020
      Bachelor of Science - BS Biomedical Sciences, General First

      Final Year Modules: Intro to Mathematical Biology with stability analysis in MATLAB, Systems Biology, Epidemiology, Microbiology, Immunology and Haematology, and Carcinogenesis.Dissertation: "Genome-Wide Association Study (GWAS) on Renal Function in Participants of Italian Ancestry" Implementing a GWAS pipeline using R and PLINK.

    • Imperial College London

      2021 - 2022
      MSc Bioinformatics and Theoretical Systems Biology Biomathematics, Bioinformatics, and Computational Biology Distinction

      (i). Bioinformatic project: "CNN transfer learning to investigate stereotyped postures in Drosophila melanogaster"Computer vision: object detection, registration, segmentation. DeepLabCut for markerless pose estimation, VGG16 transfer learning with Keras, UMAP dimensionality reduction and HDBSCAN clustering analysis. (ii). Data Analysis project:"Variational autoencoder based learning of low-dimensional latent spaces to characterize C. elegans phenotypes"Image… Show more (i). Bioinformatic project: "CNN transfer learning to investigate stereotyped postures in Drosophila melanogaster"Computer vision: object detection, registration, segmentation. DeepLabCut for markerless pose estimation, VGG16 transfer learning with Keras, UMAP dimensionality reduction and HDBSCAN clustering analysis. (ii). Data Analysis project:"Variational autoencoder based learning of low-dimensional latent spaces to characterize C. elegans phenotypes"Image analysis in Python using unsupervised approaches with PyTorch and Scikit-Learn & web development. (iii). Computing project: "A potential prognostic gene signature for neuroblastoma associated with p53-dependent NTRK1 activation and increased patient survival"Differential gene expression analysis in R using statistical analysis, survival analysis, pathway analysis and random survival forests. Modules: Bioinformatics and Systems Biology 1 & 2, Computing, Mathematical and Statistical Inference. Show less

  • Experience

    • The Pirbright Institute

      Sept 2018 - Sept 2019
      Student Virologist

      Employed molecular, cellular, and virology experimental techniques in Dalan Bailey's Viral glycoprotein group, to investigate viral glycoprotein host interactions for a group of negative-sense RNA viruses (Measles, Respiratory syncytial virus, Ebola and VSV). Publications:• Kelly, J.T.; Human, S.; Alderman, J.; Jobe, F.; Logan, L.; Rix, T.; Gonçalves-Carneiro, D.; Leung, C.; Thakur, N.; Birch, J.; Bailey, D. BST2/Tetherin Overexpression Modulates Morbillivirus Glycoprotein Production to Inhibit Cell–Cell Fusion. Viruses 2019, 11, 692.Conferences: • Microbiology Society Annual Conference, Belfast April 2019. Poster presented: "Elucidating Conserved Interactions Between Viral Glycoproteins and Cellular Factors" Show less

    • MGS Laboratories Ltd

      Mar 2021 - Sept 2021
      Microbiologist

      Worked in a microbiological contract testing laboratory primarily testing disinfectants according to CEN standard methods.

    • Dunad Therapeutics

      Nov 2022 - Sept 2023
      Machine Learning Intern

    • Imperial College London

      Sept 2023 - now
      PHD Student

      Integration and coverage estimation of multi-assay inter-lab metabolomic datasets. Part of the HUMAN Doctoral Network

  • Licenses & Certifications

  • Honors & Awards

    • Awarded to Thomas Rix
      Biochemistry Founder’s Prize - Apr 2019 Awarded £150 for a combination of excellence in biochemistryand written exposition in second-year modules in practical biochemistry
    • Awarded to Thomas Rix
      Gordon Hartman Prize - Apr 2018 Awarded £45 to the four students achieving the highest aggregatemarks across the first-year biosciences cohort.