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Yi Sing Gee

Yi Sing Gee

Followers of Yi Sing Gee960 followers
location of Yi Sing GeeMelbourne, Victoria, Australia

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  • Timeline

  • About me

    ATMCF Laboratory Manager at Monash Institute of Pharmaceutical Sciences ⌬ Bridge Industry Fellow 2022 ⌬ PhD in Organic Chemistry & Medicinal Chemistry ⌬ X/Twitter @SingThesis

  • Education

    • Industry Mentoring Network in STEM (IMNIS)

      2021 - 2022
      IMNIS Engage | Industry Mentee

      The Industry Mentoring Network in STEM (IMNIS) is a powerful opportunity for early career researchers to increase their understanding of industry and extend their professional network beyond academia.I received mentorship from Sharon Charles (Vice President of Clinical Operations @ ProPharma) in this one-year industry-led program. I also took part in a series of professional development modules in this program to develop professional skills and attributes, which can be applied to any… Show more The Industry Mentoring Network in STEM (IMNIS) is a powerful opportunity for early career researchers to increase their understanding of industry and extend their professional network beyond academia.I received mentorship from Sharon Charles (Vice President of Clinical Operations @ ProPharma) in this one-year industry-led program. I also took part in a series of professional development modules in this program to develop professional skills and attributes, which can be applied to any part of the STEM ecosystem.https://www.linkedin.com/company/imnis/ Show less

    • MTPConnect

      2019 - 2019
      The Bridge Program Pharmaceutical Commercialisation

      The Bridge Program equips researchers and entrepreneurs with the knowledge, skills and networks to enable the successful commercialisation of new pharmaceuticals.The program selects 100 participants annually from across Australia to take part in face-to-face and online training in the various components that contribute to the commercialisation of new medicines. Covering the scientific, legal, financial, clinical, regulatory and reimbursement elements of pharmaceutical… Show more The Bridge Program equips researchers and entrepreneurs with the knowledge, skills and networks to enable the successful commercialisation of new pharmaceuticals.The program selects 100 participants annually from across Australia to take part in face-to-face and online training in the various components that contribute to the commercialisation of new medicines. Covering the scientific, legal, financial, clinical, regulatory and reimbursement elements of pharmaceutical commercialisation, the program is available to researchers, entrepreneurs and associated professionals from the pharmaceutical ecosystem around Australia. Show less

    • Foon Yew High School

      2003 - 2008
      High School

      Activities and Societies: Journalist Society, Growth Group Senior Three Science 4

    • University of Wollongong

      2014 - 2018
      Doctor of Philosophy (PhD) Chemistry

      Activities and Societies: Chemistry Society Projects:*** Dual-action prodrugs for glioblastoma multiforme (GBM)GBM is the most aggressive and fatal form of brain cancer. Even though treatment options such as chemotherapy and radiation therapy are available, these treatments often cause unavoidable negative side effects. These therefore press the need of novel therapeutic approaches that can either prevent or minimise undesired side effects. Hence, we are developing a novel dual-action prodrug that is potent and selective… Show more Projects:*** Dual-action prodrugs for glioblastoma multiforme (GBM)GBM is the most aggressive and fatal form of brain cancer. Even though treatment options such as chemotherapy and radiation therapy are available, these treatments often cause unavoidable negative side effects. These therefore press the need of novel therapeutic approaches that can either prevent or minimise undesired side effects. Hence, we are developing a novel dual-action prodrug that is potent and selective in GBM.*** Bifunctional strained three-membered rings as useful synthetic scaffoldsBifunctional three-membered rings, such as cyclopropylamines and vinylcyclopropanes (VCP), are useful scaffolds in synthetic methodologies. Apart from the intrinsic ring-strain in cyclopropane that acts as a thermodynamic driving force, their reactivities are greatly influenced by the functional groups present on the ring. We are intrigued to investigate these reactivities upon activation by metal complex or catalyst. Show less

    • University of Wollongong

      2013 - 2013
      Bachelor of Science (Honours) Chemistry First Class Honours

      Thesis title: Synthesis of Novel Inhibitors of Lysine-specific Demethylase 1

    • University of Tasmania

      2009 - 2012
      Bachelor of Science Chemistry & Biochemistry

      List of completed chemistry subjects (Advanced level):* KRA331 Natural Products and Bioprospecting: High Distinction * KRA332 Physical and Analytical Methods in Chemistry: High Distinction* KRA335 Organic Chemistry: High Distinction* KRA336 Separation Science and Related Techniques: High Distinction* KRA337 Chemistry Research Project: High DistinctionList of completed biochemistry subjects (Advanced level):* CBA341 Molecular Biology and Protein… Show more List of completed chemistry subjects (Advanced level):* KRA331 Natural Products and Bioprospecting: High Distinction * KRA332 Physical and Analytical Methods in Chemistry: High Distinction* KRA335 Organic Chemistry: High Distinction* KRA336 Separation Science and Related Techniques: High Distinction* KRA337 Chemistry Research Project: High DistinctionList of completed biochemistry subjects (Advanced level):* CBA341 Molecular Biology and Protein Biochemistry: High Distinction* CBA342 Techniques in Molecular Biology and Protein Biochemistry: High Distinction* CBA343 Advanced Biochemistry and Molecular Biology: Credit* CBA344 Research Project in Biochemistry and Molecular Biology: Distinction- Completed introductory & intermediate level subjects are not listed here. Show less

  • Experience

    • University of Tasmania

      Jan 2011 - Jun 2011

      * Provide academic assistance to undergraduate students who reside on-campus. * Chip-based capillary electrophoresis.* Funded by Summer Research Scholarship Program (UTAS School of Chemistry).

      • Chemistry Tutor

        Mar 2011 - Jun 2011

      • Research Student

        Jan 2011 - Feb 2011

    • University of Tasmania

      Apr 2012 - Jun 2012
      Chemistry Tutor

      * Provide academic assistance to undergraduate students who reside on-campus.

    • CSIRO

      Nov 2013 - Jan 2014
      ANU Summer Research Scholar

      * Protein engineering and directed evolution of enzymes for improved catalytic properties. * Funded by Summer Research Scholarship Program (Australian National University).

    • University of Wollongong

      Jul 2014 - Mar 2018
      Laboratory Demonstrator

      * Demonstrated various chemistry techniques and provided guidance to undergraduate students during laboratory class for fundamental level chemistry, intermediate level organic chemistry and advanced level pharmacology* Supervised laboratory class to ensure students are performing experiments in a safe environment* Troubleshooting technical issues arise during laboratory class* Evaluated student performance and written work, return feedback to students within the timeframe set by university* Maintained records for student attendance and performance digitally* Using Adobe Captivate to develop online teaching activities for undergraduate students Show less

    • University of Technology Sydney

      Apr 2018 - Nov 2018
      Research Associate

      Working full time to conduct research on the synthesis and characterisation of boron-nitrogen heterocycles as energy storage materials.

    • Monash Institute of Pharmaceutical Sciences

      Feb 2019 - now

      * Perform and oversee a range of significant and complex research activities that includes the managing and overseeing of the chemistry laboratories, development and implementation of protocols and procedures, providing expert advice and training, and undertaking complex analysis, while ensuring a compliant and safe research environment.* Contribute to strategic and operational planning by identifying, developing and implementing systems, processes and documentation to support the activities of the facility.* Manage and oversee the facility’s chemistry laboratories, including the management of risks, the development of research protocols; ensuring all essential physical and digital resources are in place for the efficient day-to-day operation of laboratory.* Exercise strong financial management for the facility where required, including planning and allocating resources, developing funding proposals and reporting.* Manage and oversee risk, compliance, OHS and quality assurance for the facility including regular monitoring and reporting in accordance with research and other guidelines and regulations.* Develop, pursue and maintain strong partnerships, collaborations and networks with academic and other staff, relevant research bodies, service providers and functional areas. Show less * In charge of the planning, execution and project management for a broad range of drug discovery research projects, such as type-II diabetes, PET imaging agents for multiple sclerosis, acute myeloid leukaemia (AML), cardiovascular diseases, cardioprotective agents for children cancers, cardiac regenerative agents, COVID-19 and etc.* Execute the design, organic synthesis, purification and analysis of bioactive molecules for drug discovery research projects mentioned above.* Collaborate and establish strong working relationship with multiple external stakeholders (contract research organisations, biotech companies, medical researchers, biologists, X-ray crystallographers, computational scientists) to drive translational medical research.* Oversee general lab operation for a research facility of 20+ staffs and research students, in terms of safety, lab resources, scientific equipment and data management.* Maintain detailed record of experimental procedures and research data.* Highly experienced in data management for >50 drug discovery projects using digital solutions (ChemInventory, CDD Vault, LabArchives).* Provide supervision and guidance to honours students and PhD candidates.* Train students and postdocs to operate scientific equipment.* Design and deliver Advanced Organic Chemistry class & workshop for PhD candidates.* Coordinator for MedChem PhD Seminars.* Oversee logistics and transfer of research samples to/from our facility.* Financial and budget planning for research projects and lab operations.* Identify potential funding opportunities and driving grant applications.⭐ ACHIEVEMENTS ⭐* Successfully completed four TIA's Pipeline Accelerator Projects, valued at $400K in total.* Successfully secured $250K from external funding body for multiple sclerosis research.* Successfully secured infrastructure grants of $377K in total from external funding body to expand facility infrastructures and capabilities. Show less

      • Laboratory Manager (Australian Translational Medicinal Chemistry Facility)

        Apr 2024 - now

      • Research Fellow (Australian Translational Medicinal Chemistry Facility)

        Feb 2019 - Apr 2024

    • Currus Biologics Pty Ltd

      Oct 2022 - Feb 2023
      Intern | Bridge Industry Fellow

      * Performed desk based research relating to the company’s drug development program and business development activities, which include competitor landscape analysis, literature review, clinical data analysis and etc.* Attended meeting with clinical research organisations and service providers.* Carried out tasks under the direction of the company’s Chief Executive Officer and Drug Development Manager.* Funded through Bridge Industry Fellowship 2022 (1 out of 10 recipients in Australia). The fellowship program was funded by MTPConnect and facilitated by QUT.* 0.2 FTE. Show less

  • Licenses & Certifications

  • Honors & Awards

    • Awarded to Yi Sing Gee
      Bridge Industry Fellowship MTPConnect & Queensland University of Technology Jul 2022 Competitive industry-based fellowships to boost skills and advance research or technology towards commercialisation.Industry fellowship is facilitated by QUT and funded by MTPConnect’s Researcher Exchange and Development within Industry (REDI) initiative for the Australian Government’s Medical Research Future Fund (MRFF), provide up to $10,000 to support the placement of participants and alumni of the Bridge Program within industry.Successful applicants were chosen based on… Show more Competitive industry-based fellowships to boost skills and advance research or technology towards commercialisation.Industry fellowship is facilitated by QUT and funded by MTPConnect’s Researcher Exchange and Development within Industry (REDI) initiative for the Australian Government’s Medical Research Future Fund (MRFF), provide up to $10,000 to support the placement of participants and alumni of the Bridge Program within industry.Successful applicants were chosen based on their suitability in relation to potential placement partners, stage of career, development possibilities and commercial potential of their research or technology. Show less
    • Awarded to Yi Sing Gee
      Poster Award Southern Highlands Conference on Heterocyclic Chemistry Aug 2016 Recognition of conference poster contribution, as judged by quality and significance of the work and its clarity of presentation.
    • Awarded to Yi Sing Gee
      Best Research Presentation Awards School of Chemistry, University of Wollongong 2014 Highly commended talk by a first year PhD student at School of Chemistry's 2014 Annual Research Conference.
    • Awarded to Yi Sing Gee
      Bert Halpern Prize School of Chemistry, University of Wollongong 2013 The best first class honours graduate in chemistry.
    • Awarded to Yi Sing Gee
      Dean's Merit List for 2013 Faculty of Science, Medicine and Health, University of Wollongong 2013 Having achieved a ranking in the top 5% of students in the faculty.
    • Awarded to Yi Sing Gee
      Dean's Roll of Excellence Faculty of Science, Engineering and Technology, University of Tasmania 2012 Outstanding academic performance in 2012.
    • Awarded to Yi Sing Gee
      E.J. Browne Memorial Prize University of Tasmania 2012 Outstanding proficiency in 3rd year organic chemistry.
    • Awarded to Yi Sing Gee
      Royal Australian Chemical Institute 3rd Year Prize University of Tasmania 2012 Most outstanding graduate in chemistry.
    • Awarded to Yi Sing Gee
      J.N. Baxter Memorial Prize University of Tasmania 2011 Outstanding proficiency in 2nd year organic chemistry.

  • Volunteer Experience

    • IYPT Expo Volunteer

      Issued by The Royal Australian Chemical Institute on Aug 2019
      The Royal Australian Chemical InstituteAssociated with Yi Sing Gee

    • Volunteer

      Issued by Sydney Science Festival 2017 on Aug 2017
      Sydney Science Festival 2017Associated with Yi Sing Gee

    • Chair for Conference

      Issued by School of Chemistry, University of Wollongong on Nov 2016
      School of Chemistry, University of WollongongAssociated with Yi Sing Gee

    • Volunteer

      Issued by Monash University on Nov 2022
      Monash UniversityAssociated with Yi Sing Gee

    • Volunteer

      Issued by Australian Translational Medicinal Chemistry Facility (ATMCF) on Jul 2022
      Australian Translational Medicinal Chemistry Facility (ATMCF)Associated with Yi Sing Gee

    • Poster Judge

      Issued by Monash University on Nov 2021
      Monash UniversityAssociated with Yi Sing Gee

    • Poster Judge

      Issued by Monash University on Oct 2020
      Monash UniversityAssociated with Yi Sing Gee

    • Volunteer | Chair for Seminar

      Issued by University of Technology Sydney on Nov 2018
      University of Technology SydneyAssociated with Yi Sing Gee