Florence Flick, PhD

Experience

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  Marine Nationale

  Sept 2006 - Jun 2007

  Intern

  • Introduction to military operation, navigation and rearms handling. • First aid training.• Boating license.

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  Université de Strasbourg

  Sept 2010 - Jun 2013

  Student Job

  • Ressources management and customer relations.• Ensuring customers support and satisfaction.• Helping customers find the items they are looking for. • Training on the library research platform.

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  AIESEC

  Mar 2011 - Mar 2018

  Volunteer

  AIESEC is the world's largest youth-run organization developing the leadership potential of young people. Present in 120+ countries and territories across 2600 universities, AIESEC provides students and recent graduates with life-changing experiences to intern or volunteer abroad within partner organizations.It allowed me to• Work across a wide variety of cultures and with different personalities.• Work remotely and on-site with different entities - Estonia, Ethiopia, Bolivia, Egypt, Nigeria, France, Mauritius, South Africa – as CEO for a French local chapter as well as Content, Brand and Creative Director.• Deliver workshops and educational sessions on Marketing and on the organizational platform aiesec.org in Senegal, Estonia, France, South Africa and Ethiopia.• Manage the Regional Support Team for Internal Communication in Middle East and Africa.• Lead the Global Support Team Communication for “Youth Speak” under Dmitry Dubovik.• Cover as a photographer multiple international conferences in Taiwan, India, Poland and more recently Romania.• Cover as a photographer Youth Speak Forum in Jordan.• Move to the Philippines to volunteer with Gawad Kalinga. Show less

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  Centre national de la recherche scientifique

  Mar 2011 - May 2011

  Undergraduate Student Researcher

  This undergrad experience in the CNRS Molecular Genetics, Genomics and Microbiology Laboratory was performed under Dr. Anne Friedrich.• Establishment of a Genome browser platform.

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  INSERM; University of Strasbourg

  Aug 2013 - Sept 2016

  Graduate Research Assistant in Cell Mechanobiology

  Research in the INSERM BioMaterials & BioEngineering Laboratory focuses on developing and characterizing new generations of biomaterials and their integration in the tissue microenvironment by mimicking biomechanical cues. This PhD research was performed under Dr. Dominique Vautier & Pr. Youssef Haikel. This work led to 2 peer-reviewed publications.• Focus on the understanding of the effect of cellular microenvironment stiffness on chromatin plasticity.• Investigation of the fate of epithelial healthy and cancer cells as well as interaction at cell/materials interface.• Mechanical characterization of polyelectrolytes multilayers.• Cell culture experience with epithelial cells (PtK2, SW480, 3T3).• Use of diverse imaging techniques – Epifluorescence Microscopy (Nikon Eclipse Ti-S), Confocal Microscopy (Zeiss LSM 510), Fluorescence Recovery After Photobleaching (FRAP), Timelapse (Nikon Ti-E).• Use of highly flexible software for data analysis – FIJI/ImageJ.• Use of a wide range of analysis techniques such as Immunocytochemistry, Life/Dead assays, and Pharmaceutical Inhibition.INSERM Workshops: • Live imaging of morphogenesis in 4D• Single cell sequencing: from basic research to clinical application Show less

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  European Symposium on Vascular Biomaterials

  May 2017 - Oct 2017

  Communication Manager

  The European Symposium on Vascular Biomaterials – ESVB – is the largest European biannual event dedicated to biomaterials applied to vascular and endovascular surgery. Established in 2011, it gathers worldwide and renowned scientists, surgeons, radiologist, industries, startups and everyone involved in the research and the use of biomaterials in the vascular and endovascular field. It aims to promote knowledge exchanges, develop a multidisciplinary approach as well as creating an interactive platform allowing for productive exchanges and durable collaborations. Show less

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  GEPROVAS

  May 2017 - Dec 2017

  Communication Manager

  Communication manager for an European Symposium in Vascular Biomaterials (ESVB 2017) in a unique worldwide structure dedicated to the forensic engineering study of vascular prosthesis (GEPROVAS).• Elaboration of a communication plan and content creation.• Communicate complex idea and adapt the communication to the target audience.• Creation of a strong network and initiation of new collaborations with vascular scientific societies (e.g. SOLACI).• In charge of the creation of a startup competition in the field of vascular technologies.• Press kits Show less

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  Science FromAtoZ

  Oct 2018 - Nov 2020

  Professional Freelancer: Science communication, Event Organization and Photography

  • Communication for GEPROVAS - Press kit and content creation.• First exhibit at the St. Louis Arts Chamber of Commerce Virtual Underground Art Show• Event and Conference photographer for various organization since 2013 – AIESEC International, AIESEC in Jordan, the United Nations Association of St. Louis, Venture Café, Doorways, Cupids Undie Run St. Louis and the St. Louis Aquarium Foundation. • Photographer for the CAFA-RSO since 2013• Beginning Artist Member of the St. Louis Camera Club• Member of the St. Louis Art Chamber of Commerce• Third Place - Category B for "Black Lives Matter" in the Saint-Louis Camera Club September Photojournalism Competition• Second Place - Category B for "Rolling Storm over the Eads Bridge" in the Saint-Louis Camera Club October Open Digital Competition on the thematic "Bridge" Show less

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  ByTheArch

  Nov 2018 - now

  Advocate

  Sharing about my #AYearByTheArch #STLMade experience in St. Louis, the Gateway Arch City and the events it hosts through photography and journaling.• Captured Production Stills and Promotional Images for the musical "The Mad Ones" directed by Kevin Corpuz (The Tesseract Theatre Company) at The Marcelle.

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  Washington University in St. Louis

  Dec 2018 - Apr 2021

  Research in the Cellular Mechanobiology Laboratory focuses on understanding how normal and cancerous cells sense and remember varying biomechanical cues present in the tissue microenvironment. Postdoctoral research performed under Dr. Amit Pathak. This work will lead to a paper currently in preparation.• Focus on the effect of polyacrylamide collagen-coated gels stiffness on the nuclear architecture of epithelial breast cells.• Mechanical characterization of polyacrylamide gels.• Cell culture experience with epithelial cells (MCF10AWT, MDA-MB-231 and derived cell lines) and macrophages (RAW 264.7).• Use of diverse imaging techniques – Confocal Microscopy (ZEISS LSM 880 Confocal with/without Airyscan), Fluorescence Recovery After Photobleaching (FRAP), Timelapse (Zeiss Celldiscoverer 7, Zeiss Axio Observer 3 and Olympus IX81) and Transmission Electron Microscopy (JEOL JEM-1400 120kV TEM).• Use of highly flexible software for data analysis – FIJI/ImageJ, Imaris, MATLAB.• Use of a wide range of analysis techniques – Western Blot, Immunocytochemistry. Show less Research in the Cellular Mechanobiology Laboratory focuses on understanding how normal and cancerous cells sense and remember varying biomechanical cues present in the tissue microenvironment. Visiting Scholar research performed under Dr. Amit Pathak. This work was extended as a Postdoctoral Research with a broader focus on Nuclear Mechanobiology.• Focus on the effect of polyacrylamide collagen-coated gels stiffness on the chromatin organization of epithelial breast cells.• Mechanical characterization of polyacrylamide gels.• First hand introductory experience with Zebrafish (Danio rerio) as in vivo model. Show less

  • Postdoctoral Research Associate in Cell Mechanobiology

    Nov 2019 - Apr 2021

  • Visiting Research Associate in Cell Mechanobiology

    Dec 2018 - Nov 2019
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  Self-employed

  May 2021 - Aug 2022

  Finalizing my post-doctoral project on Nuclear Mechanobiology

  I am currently collaborating with my former post-doc laboratory on the preparation and submission of the research paper, actively networking and looking for new career opportunities ideally in Cell MechanobiologyI am simultaneously as well doing an intensive german course with the Goethe Institute in 📍 Hamburg, Germany 🇩🇪 and through online classes.• Animation Mentor Autodesk Maya Workshops: Animation Basics• Intensive German classes

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  Picard Surgelés

  Dec 2021 - Jan 2022

  Seasonal Store Associate

  Picard Surgelés is a French food company specializing in the manufacture and retail distribution of frozen products.- Providing customers with an excellent buying experience- Reinforcing the team during the holiday season- Assisting in maintaining a clean and organized product floor, and ensuring a welcoming, customer-friendly environment- Managing financial transactions and purchases using cash registers and appropriate software systems- Maintaining updated knowledge on current products, pricing, and promotions- Greeting customers and providing them with purchasing options based on their needs and wants- Following through on an exceptional customer experience by presenting customers with product promotions and sale opportunities as identified through conversation- Refilling the freezers and performing stock rotations Show less

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  Washington University School of Medicine in St. Louis

  Aug 2022 - now

  • Focus on the developing a pulsatile conduit made from hi-PSC derived cardiomyocytes through Additional Ventures Cures Collaborative's mission to find a functional cure to Single Ventricle Disease in collaborations with researchers from multiple universities.• Systematic comparison of the different methods or producing and maturing cardiomyocytes for the pulsatile conduit using micro-engineered heart tissue as screening tool.• Secondary focus on the effect of radiation on ventricular arrhythmia in a porcine model of heart failure in collaboration with Christian Zemlin and the Department of Comparative Medicine.• Preparation of stencils for engineered tissues. • Engineered tissues and animal models hearts optical mapping.• Electrophysiological characterization of micro-engineered heart tissue, meso-scale dynamic engineered heart tissue and porcine heart.• Use of highly flexible software for data analysis – FIJI/ImageJ, MATLAB. Including a dedicated optocardiography analysis MATLAB powered software.• Cell culture experience with hi-PSC cardiomyocytes.• Large animal model experience (Porcine model).• Attended the 2022 Single Ventricle Investigator Meeting in Baltimore, MD, USA and presented a poster on "Electrophysiological characterization of engineered micro-heart tissues derived from human induced pluripotent stem cells – on the search for the optimal parameters" in the 2023 Weinstein Conference on cardiovascular development and regeneration in San Diego, CA, USA. Presented two posters during the Center for Cardiovascular Research Day in St. Louis, MO, USA on “Generating engineered cardiac tissues with high conduction velocity: Electrophysiological implications of 3D vs 2D Notch activation” and “Electrophysiological Characterization of Engineered micro-Heart Tissues derived from Human Induced Pluripotent Stem Cells”. Show less

  • Staff Scientist

    Aug 2024 - now

  • Staff Scientist working on Tissue Engineering and Single Ventricle Defects

    Aug 2022 - Jul 2024
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  The Tesseract Theatre Company

  Oct 2023 - now

  Theatre Photographer (Volunteer)

  Capturing pre-production images during rehearsal period and document the production of musicals and plays produced by The Tesseract Theatre Company in the Greater St. Louis region. Past productions• “The Mad Ones” by Bree Lowdermilk, Kait Kerrigan, and Kate Kerrigan directed by Kevin Corpuz at The Marcelle.• Regional premiere of "The Inheritance" by Matthew Lopez directed by Stephen Peirick at The Marcelle• The 2024 Festival of New Musicals with “My Heart Says Go” by Jorge Rivera-Herrans directed by Brittanie Gunn and “Cascade’s Fire” by Taylor Gruenloh.• "Anastasia: The Musical" directed by Brittanie Gunn. Show less