
Rachel Pass BSc MRes PhD
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About me
Postdoctoral Scholar
Education

Bath University
2012 - 2013Masters of Research (MRes) Biology/Biological Sciences, GeneralActivities and Societies: First Aid (St John's Ambulance), Climbing, Latin and Ballroom Dancing Attended a three day neuroanatomy course at UCL with Neurocourses UK. Consisted of a series of in depth lectures and practical sessions, where I gained experience handling and examining human brains. As a result I also developed an understanding of the Human Tissue Act (2004).Modules completed:- Critical Research and Analytical Skills- Frontiers of Neuroscience- Human Developmental Disorders- Modern Methods of Researching Neurodegeneration- Clinical and… Show more Attended a three day neuroanatomy course at UCL with Neurocourses UK. Consisted of a series of in depth lectures and practical sessions, where I gained experience handling and examining human brains. As a result I also developed an understanding of the Human Tissue Act (2004).Modules completed:- Critical Research and Analytical Skills- Frontiers of Neuroscience- Human Developmental Disorders- Modern Methods of Researching Neurodegeneration- Clinical and Translational MedicineProjects completed (two five month laboratory based)The impact of Klf4 overexpression in somatic cells with Dr Tony Perry (Mammalian Molecular Embryology)The role of zinc and manganese in Prion disease with Prof David Brain (Neurodegeneration Laboratory)The Show less

Cardiff University / Prifysgol Caerdydd
2015 - 2018Doctor of Philosophy (Ph.D.) NeuroscienceActivities and Societies: Contributed to setting up The Brain Domain, a public outreach endeavoring to introduce neuroscience topics to non-scientists and provide an opportunity for young neuroscientists to improve their science writing skills. I have so far written 3 articles. https://thebraindomain.org/author/raeredqueen/ Project Title: Characteristics of the effects of genetic variation in rodent models of risk for Schizophrenia and neurodevelopmental disorder.Supervisors: Dr Kerrie Thomas, Prof Jeremy Hall, Prof Lawrence WilkinsonThis project will focus on copy number variants (CNV) spanning DLG2, which are associated with increased risk of schizophrenia. Although these mutations are rare they are highly penetrant.DLG2 (aka PSD-93) is part of the post-synaptic density, a structure found… Show more Project Title: Characteristics of the effects of genetic variation in rodent models of risk for Schizophrenia and neurodevelopmental disorder.Supervisors: Dr Kerrie Thomas, Prof Jeremy Hall, Prof Lawrence WilkinsonThis project will focus on copy number variants (CNV) spanning DLG2, which are associated with increased risk of schizophrenia. Although these mutations are rare they are highly penetrant.DLG2 (aka PSD-93) is part of the post-synaptic density, a structure found with dendritic spines and associates with the post-synaptic membrane. Microdeletions of DLG2 have been associated with schizophrenia. This project is part of, and funded by, the larger DEFINE project which is studying the effect of high-penetrance mutations conferring risk for a spectrum of mental disorders that cross diagnostic boundaries. Show less

Keele University
2009 - 2012Bachelor of Science (BSc) Biology & Psychology (hons) 2:1Activities and Societies: KDS Karate Vice Captain (2011/12), KDS Karate Social Secretary (2010/11), University Paintball Team Member (2010-12), Paintball Society Social Secretary (2011/12), Biology Dissertation carried out in Honduras with Operation Wallacea (http://www.opwall.com/). Awarded Colours for my Paintball committee position (2012). During my third year at Keele i was also selected to play for the National GB Women's Paintball team, which competed at the European Women's Nations Cup in Bitburg, Germany, in May 2012.Key modules include:- Genetics and Evolution- Cellular and Molecular Biology- Development and Evolution of Nervous Systems- Symbiotic Interactions- Biology Research Skills- Four Research Methods in Psychology (Covering Statistics, Experimental Designs, etc)- Biological… Show more During my third year at Keele i was also selected to play for the National GB Women's Paintball team, which competed at the European Women's Nations Cup in Bitburg, Germany, in May 2012.Key modules include:- Genetics and Evolution- Cellular and Molecular Biology- Development and Evolution of Nervous Systems- Symbiotic Interactions- Biology Research Skills- Four Research Methods in Psychology (Covering Statistics, Experimental Designs, etc)- Biological Basis of Brain Disease- Clinical Pathology- Human Evolution- Psychobiology- Two Biological and Cognitive PsychologyDissertation titles:Psychology: The impact of a medio-dorsal thalamic lesion on a patient's recognition memory.Biology: The effect of elevation on the presence of the chytrid fungus Batrachochytrium dendrobatidis in amphibian populations in Cusuco National Park, Honduras. Show less
Experience

Longlevens Vets
Jan 2005 - Sept 2005VolunteerDuties involved shadowing and assisting the Vets, stock work and work on reception.

British Heart Foundation
Jun 2009 - Sept 2009VolunteerResponsibilities included working on the till, assisting colleagues with tasks and queries, and responding to customer queries and complaints in a professional, appropriate manner. Undertook all aspects of stock management in the shop including stock check, restock of the store, stock rotation, preparation of stock for the shop floor and display maintenance.

SLG Beauty
Jul 2010 - Aug 2010Factory WorkerDuties included the preparation and packaging of products for dispatch to businesses, and the quality control of products to a high standard prior to packaging.

Unreal Paintball
Oct 2011 - Jun 2012MarshalMaintenance, preparation and cleaning of paintball equipment to ensure a safe, enjoyable customer experience. Monitored and organized groups of up to 80 people, assisted customers and responded to their queries, as well as providing leadership and direction to colleagues. Assumed responsibility for stock checks and worked on the till, dealing with customer transactions. Responsible for thorough site clean at the end of each work day.

Currys PC World
Jul 2012 - Sept 2012Sales AdvisorA very target driven role which involved assisting and advising customers on choosing current technology to suit their needs, offering guidance on how to use their technology, and some technical work for the Knowhow services.

The Wheelwrights Arms
Nov 2012 - Aug 2013Bar/Waitressing StaffInvolved a variety of tasks, both in the restaurant and hotel, if required. Took bookings, served customers, maintained high standard of the pub, dealing with complaints.

Blue Arrow
Oct 2013 - Mar 2014Events Steward & Bar StaffKey duties involved crowd control, ensuring enforcement of health and safety regulations, acted as a point of information, part of evacuation team if required.During Gold Cup week 2014 worked in three bars, as part of the Jockey Club bar staff.

Waterstones
Nov 2013 - Jan 2014Bookseller
Cardiff Brain Repair Group
Jul 2014 - Aug 2014VolunteerAssisting Dr Amy Reddington with PhD continutation work three days a week.This included brain sectioning using both microtomes and cyrostats and immunohistochemistry on these samples.

Neuroscience and Mental Health Research Institute, Cardiff University
Sept 2014 - Oct 2015Research TechnicianMy project aims to discover phenotypes associated with neural precursor cells carrying a CYFIP1 or 15q11.2 CNV. This will be achieved by deriving neural precursor cells from both ES and iPS cells and examining their motility through transwell assays and live cell imaging. Additionally I am creating a CYFIP1 haploinsufficent cell line, that mimics the human condition, using the CRISPR-Cas9 system and then assaying the motility of these cells. Ultimately the aim will be to compare the CRISPR mutant neural precursor cells to 15q11.2 patient derived neural precursor cells. I am also a Fire Warden for our floor and actively involved in science communication.I officially ended this position when I took up my PhD position, but have continued to help where possible in the continuation of this work.This included training of a masters student taking over the project, and additionally genotyping a new rodent line. Show less

Cardiff University / Prifysgol Caerdydd
Oct 2018 - May 2021This MRC funded project focuses on the impact of chronic treatment with a range of drugs, given to Parkinson's disease patients, in a 6-OHDA rat model which also received human ES cell grafts. This includes assessment on a range of key behavioural tasks, and IHC characterisation of graft survival, phenotype and inflammatory responses.
Research Associate
Sept 2020 - May 2021Research Assistant
Oct 2018 - Sept 2020
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Okinawa Institute of Science and Technology Graduate University (OIST)
Jul 2021 - nowPostdoctoral Scholar
Licenses & Certifications

Personal License
UK Home OfficeJan 2016
Honors & Awards
- Awarded to Rachel Pass BSc MRes PhDKakenhi Early Career Grant JSPS Feb 2025
- Awarded to Rachel Pass BSc MRes PhDTravel Grant NECTAR Nov 2019 Received travel grant award for abstract submitted for a 5 minute data blitz at NECTAR 2019. I developed the presentation but it was given by my undergraduate student.
- Awarded to Rachel Pass BSc MRes PhDGuarantors of Brain Travel Grant Guarantors of Brain Jun 2018 Travel grant to present a poster at FENS 2018.
- Awarded to Rachel Pass BSc MRes PhDMQ Travel Grant MQ Jan 2018 Awarded a grant to attend the MQ Mental Health Science Meeting 2018 where I presented a poster.
- Awarded to Rachel Pass BSc MRes PhDBNA Bursary British Neuroscience Association Feb 2017 Bursary awarded to attend the BNA Festival of Neuroscience 2017 and present a poster.
- Awarded to Rachel Pass BSc MRes PhDNMHRI Travel Grant NMHRI Nov 2016 Travel grant awarded to attend to British Neuroscience Association 2017 Festival of Neuroscience.
- Awarded to Rachel Pass BSc MRes PhDImage included in beautiful science colouring book Thermofisher Scientific Oct 2016 My image of neural precursor cells derived from human iPS cells was selected to be included in their beautiful science colouring book.
- Awarded to Rachel Pass BSc MRes PhDGold Sponorship Primerdesign Feb 2016 Company sponsorship from Primerdesign to support my research project involving PCR technology used to measure gene expression
- Awarded to Rachel Pass BSc MRes PhDHome Office Personal Licence Home Office Jan 2016
Volunteer Experience
Ambassador
Issued by STEMNET on Nov 2014
Associated with Rachel Pass BSc MRes PhDVolunteer
Issued by St Johns Ambulance on Feb 2016
Associated with Rachel Pass BSc MRes PhDDissertation Research Student
Issued by Operation Wallacea on Jun 2011
Associated with Rachel Pass BSc MRes PhD
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