Jessica De Greef

Experience

• 

  Universiteit Leiden

  Sept 2004 - Aug 2008

  PhD student

  My project focused on the epigenetic disease mechanism that plays a role in the pathogenesis of facioscapulohumeral muscular dystrophy (FSHD) using Southern blot analysis, sodium bisulphite sequencing and chromatin immunoprecipitation.

• 

  Leiden University Medical Center

  Sept 2008 - Aug 2010

  Postdoctoral researcher, department of Human Genetics

  My project focused on the identification of a second gene for the immunodeficiency, centromeric instability and facial anomalies syndrome (ICF) syndrome using exome sequencing.

• 

  University of Iowa Health Care

  Nov 2010 - Mar 2015

  Postdoctoral Research Scholar, department of Molecular Physiology & Biophysics

  My projects focused on the role of collagen VI in skeletal muscle pathology and function and on the function of the N-terminal domain of α-dystroglycan in Influenza A virus proliferation.

• 

  Leiden University Medical Center

  Apr 2015 - now

  My group focuses on in vitro and in vivo disease modeling of neuromuscular disorders, with a main interest in facioscapulohumeral muscular dystrophy. My project focused on the consequences of Smchd1 haploinsufficiency in transgenic FSHD mice.

  • Assistant Professor

    May 2020 - now

  • Senior Researcher

    Aug 2017 - Apr 2020

  • Researcher

    Apr 2015 - Jul 2017