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Gregorio Naredo

Gregorio Naredo

Peptide Scientist

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  • Timeline

  • About me

    Senior Chemical Compliance Manager at British American Tobacco

  • Education

    • University of Bristol

      2001 - 2005
      PhD Chemistry

      “Towards Steroidal Based Histidine Rich Pseudoenzymatic Catalysts via Solid-Phase Combinatorial Chemistry”. My thesis involved steroid chemistry and solid phase combinatorial synthesis. I synthesised orthogonally protected triamino steroidal scaffolds based on cholic acid. On the process I developed an efficient, environmentally friendly and selective method for secondary alcohol oxidation in steroids. The steroidal scaffold was used on one-bead one-compound library comprising a… Show more “Towards Steroidal Based Histidine Rich Pseudoenzymatic Catalysts via Solid-Phase Combinatorial Chemistry”. My thesis involved steroid chemistry and solid phase combinatorial synthesis. I synthesised orthogonally protected triamino steroidal scaffolds based on cholic acid. On the process I developed an efficient, environmentally friendly and selective method for secondary alcohol oxidation in steroids. The steroidal scaffold was used on one-bead one-compound library comprising a photo-cleavable linker, the triamino cholate and peptide sequences build by solid phase combinatorial chemistry. Colorimetric assay and on-bead screening for catalytic activity provided several active members. Show less

    • Universidad de Oviedo

      1994 - 2000
      BSc Chemistry

      Double specialisation in Analytical and Organic Chemistry

    • Universidad de Oviedo

      2000 - 2001
      Postgraduate Specialisation Biochemistry

      Postgraduate one year course in biochemistry

  • Experience

    • Almac Group

      Jun 2005 - May 2007
      Peptide Scientist

      Synthesis of pyridine and quinoline-based metal chelating molecules for peptide tagging and purification. Solid phase peptide synthesis and optimization of on-bead peptide tagging strategies.Method development of IMAC (Ion Metal Affinity Chromatography) peptide purification strategies covering comprehensive metal ion and resin screening and chromatography optimizationSynthesis novel aminoacridine tags for lifetime fluorescence peptide bioassay.

    • The University of Edinburgh

      Jun 2007 - Sept 2014

      De-novo setting of synthesis facilities at the School of Medicine Endocrinology Centre focusing in modern organic chemistry methods (microwave, automated flash chromatography) to support clinical research and analytical method development.Development of 19F-Magnetic Resonance Spectroscopy as non-invasive tool for monitoring hepatic reductase activity in-vivo.Selection and sourcing/synthesis of steroidal and non-steroidal fluorinated tracers forin-vitro (cell culture, NMR, LC-MS/MS) and in-vivo screening (rodents, MRI)Synthesis and purification of enzyme substrates and metabolites. Show less

      • WTCRF Postdoctoral Research Fellow

        Sept 2010 - Sept 2014

      • Postdoctoral Research Fellow

        Jun 2007 - Aug 2010

    • BAT

      Oct 2014 - now

      Global chemical compliance management (GHS, REACH/CLP, Chemical Inventories) across traditional and new categories portfolios. Manager of the SDS and CLP label creation teams for e-Liquid and Oral products. Project Board and Key stakeholder on the IT implementation of 3E-SAP SDS creation and 3E-Notify PCN notification platforms Lead on the development and implementation of efficient processes throughout BAT to enable chemical and product compliance through Development and Deploy stages. Show less

      • Product Regulatory&Chemical Compliance Senior Manager

        Jan 2022 - now

      • Manager - Compliance Reporting Specialist II

        May 2020 - Dec 2021

      • Manager - Compliance Technical Specialist II

        Jan 2017 - Apr 2020

      • Technical Manager - Analytical Scientist II

        Oct 2014 - Dec 2016

  • Licenses & Certifications

    • PRINCE2 Practitioner in Project Management

      AXELOS Global Best Practice
      Nov 2015

    • How to Innovate and Stay Relevant in Times of Change and Uncertainty

      LinkedIn
      Nov 2023
      View certificate certificate

    • Chartered Chemist

      Royal Society of Chemistry
      Jan 2011

    • Learning Design Thinking

      LinkedIn
      Nov 2023
      View certificate certificate

    • Embracing Unexpected Change

      LinkedIn
      May 2020
      View certificate certificate

    • Virtual Pathways to Leadership®

      Verus Global
      Mar 2022
      View certificate certificate

    • Adaptive Project Leadership

      LinkedIn
      Nov 2019
      View certificate certificate

    • Dangerous Goods Safety Adviser - All classes by Road

      SQA – Scottish Qualifications Authority
      Jan 2024

    • Developing Self-Awareness

      LinkedIn
      Oct 2023
      View certificate certificate

    • 7 Essential Learnings

      BAT
      Dec 2023
      View certificate certificate