David Vadnais

Experience

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  N.M.F.S

  Jun 1999 - Aug 1999

  Biological Science Lab technician

  Conducted field identification, recordings and data entry on Long Island Sound marine species Operated field equipment such as YSI and binary tagging devices during boating excursionsCarried out dissection gut content analysis and benthic sled sample processingResponsible for coordinating and instructing Volunteers and internsDepended upon to train new hires, interns, and volunteers on sampling techniques, field identification, and various laboratory techniques

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  Southern Connecticut State University

  Sept 1999 - May 2000

  Independent Study

  Tested and maintained my own in vitro cell line for the purpose of dose testing on cancer cellsGained experience with cellular assaying, Gram staining, cell counting, stereo-microscopes, and aseptic techniquesSuccessfully maintained research notebook on all research and delivered weekly updates on the status of cell line and experiments

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  Schick-Wilkinson

  Mar 2001 - Oct 2006

  Technician

  Responsible for running daily testing of product, corrosion resistance and drag force levels. Participating and collaborating on team projects throughout the laboratory Developing new curing processes where I improved corrosion protection Conducting tests on New Age Hardness Testers, Electron scanning microscope and MTT Tensile testerAnalyze in coming raw material for production purposes

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  CGI Pharmaceuticals, Inc.

  Nov 2006 - Jul 2010

  High Throughput Screening: Enable early drug discovery efforts by screening chemical matter through a variety of biochemical (LANCE TR-FRET, LanthaScreen TR-FRET and Scintillation Proximity (SPA) formats) and cell-based proliferation assays. Contribute to the development and validation of biochemical kinase assays and assays for further compound profiling. Responsible for day-to-day operation of screening efforts, including both primary screening as well as screening through secondary kinase selectivity assays. Assure high data quality through successfully combining knowledge of theories and application of biological techniques with precise laboratory skills.Automation Support: Expert in operating, optimizing, and troubleshooting liquid handlers (Tecan TEMO and Eppendorf Epmotion) and plate reader (Envision). Informatics: Facilitated development and integration of web-based LIMS system for automated data collection, quality control, and data validation. Provided end-user feedback to software developers to assure software integration into to HTS processes. Compound Management: Responsible for compound repository storage and maintenance of kinase inhibitor-rich compound library. Coordinate shipments of compounds to contract research organizations and academic collaborators. Show less High Throughput Screening: Enable early drug discovery efforts by screening chemical matter through a variety of biochemical (LANCE TR-FRET, LanthaScreen TR-FRET and Scintillation Proximity (SPA) formats) and cell-based proliferation assays. Contribute to the development and validation of biochemical kinase assays and assays for further compound profiling. Responsible for day-to-day operation of screening efforts, including both primary screening as well as screening through secondary kinase selectivity assays. Assure high data quality through successfully combining knowledge of theories and application of biological techniques with precise laboratory skills.Automation Support: Expert in operating, optimizing, and troubleshooting liquid handlers (Tecan TEMO and Eppendorf Epmotion) and plate reader (Envision). Informatics: Facilitated development and integration of web-based LIMS system for automated data collection, quality control, and data validation. Provided end-user feedback to software developers to assure software integration into to HTS processes. Compound Management: Responsible for compound repository storage and maintenance of kinase inhibitor-rich compound library. Coordinate shipments of compounds to contract research organizations and academic collaborators. Show less

  • Research Associate II

    Dec 2009 - Jul 2010

  • Research Associate I

    Nov 2006 - Dec 2009
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  Pfizer Pharmaceuticals

  Nov 2010 - May 2011

  Biology Research Scientist (Contractor)

  • Contributed to the development and validation of a cell based assay with ELISA and cell toxicity readouts• Screened multiple small molecule libraries and confirmed hits• Supported SAR medical chemistry efforts by obtaining dose-response (EC50) data for compounds of interest• Used automated screening equipment, liquid handling systems (Multi Drop, Biomek FX), plate reader (Envision) and automated data analysis• Produced highly accurate and clear records of experiments following company policy and procedures• Collected and presented research results during laboratory group meetings Show less

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  Core Informatics

  Jun 2011 - Mar 2017

  Senior Customer Support Specialist

  Leveraged in-depth knowledge of science to partner with business clients involved in pharmaceutical, BioTech, energy, etc to assess requirements and provide ongoing support to implement solutions and resolve issues related to web based SaaS and PaaS laboratory data management software. Address and analyze customer support requests, conducting root cause analysis to address the situation. Deploy the latest version of the Core Informatics application across customer systems. Monitor and maintain documentation detail for successive software deployments. Generate knowledgebase articles as a vital resource for internal and customer use. Key Accomplishments:• Resolve issues for end-users by leveraging Zendesk to promptly field, analyze, and handle customer support requests.• Exercise scientific knowledge to translate end-user problems into actionable activities for product development teams.• Collaborate with multiple teams such as Customer Success, Education, Product Development and Technical Operations to pinpoint the root cause of issues and formulate programs to mitigate issues and enact proactive solutions. Show less

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  Thermo Fisher Scientific

  Mar 2017 - now

  Leveraged in-depth knowledge of science to partner with business clients involved in pharmaceutical, BioTech, energy, etc to assess requirements and provide ongoing support to implement solutions and resolve issues related to web based SaaS and PaaS laboratory data management software. Address and analyze customer support requests, conducting root cause analysis to address the situation. Deploy the latest version of the Core Informatics application across customer systems. Monitor and maintain documentation detail for successive software deployments. Generate knowledgebase articles as a vital resource for internal and customer use.Key Accomplishments:• Resolve issues for end-users by leveraging Zendesk to promptly field, analyze, and handle customer support requests.• Exercise scientific knowledge to translate end-user problems into actionable activities for product development teams.• Collaborate with multiple teams such as Customer Success, Education, Product Development and Technical Operations to pinpoint the root cause of issues and formulate programs to mitigate issues and enact proactive solutions. Show less

  • Staff Product Owner

    Feb 2021 - now

  • Senior Support Specialist

    Mar 2017 - Feb 2021