Talk to sales Try for Free
Barbara Konarkowska

Barbara Konarkowska

Research Technician

Followers of Barbara Konarkowska18 followers
location of Barbara KonarkowskaAuckland, Auckland, New Zealand

Connect with Barbara Konarkowska to Send Message

Connect

Connect with Barbara Konarkowska to Send Message

Connect

  • Timeline

  • About me

    New Product Development Principal Scientist - Validation at Douglas Pharmaceuticals Ltd.

  • Education

    • The University of Auckland

      1995 - 1997
      Master of Science - MS First Class Honours

      Molecular biomedical research under the supervision of Professor Garth J. S. Cooper. Thesis (MSc-Biological Sciences)--University of Auckland, 1997: "Studies on the molecular biology of leptin".

    • The University of Auckland

      1999 - 2005
      Doctor of Philosophy (PhD) BIOLOGICAL AND BIOMEDICAL SCIENCES

      Doctoral research studies in the field of molecular biomedicine under the supervision of Professor Garth J. S. Cooper. Thesis title: "Molecular mechanism of amylin-induced apoptosis of pancreatic beta-cells".Publications:Saafi E, Konarkowska B, Zhang S, Kistler J & Cooper G (2001). "Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet β-cells." Cell Biology International 25: 339-350.Aitken J, Loomes K… Show more Doctoral research studies in the field of molecular biomedicine under the supervision of Professor Garth J. S. Cooper. Thesis title: "Molecular mechanism of amylin-induced apoptosis of pancreatic beta-cells".Publications:Saafi E, Konarkowska B, Zhang S, Kistler J & Cooper G (2001). "Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet β-cells." Cell Biology International 25: 339-350.Aitken J, Loomes K, Konarkowska B & Cooper G (2003) Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid. The Biochemical Journal. 374: 779-784. Konarkowska B, Aitken J, Kistler J, Zhang S & Cooper G (2005). Thiol reducing compounds prevent human amylin-evoked cytotoxicity. The FEBS Journal. 272: 4949-4959.Konarkowska B, Aitken J, Kistler J, Zhang S & Cooper G (2006) The aggregation potential of human amylin determines its cytotoxicity towards islet β-cells. The FEBS Journal. 273: 3614-3624. Show less

  • Experience

    • The University of Auckland

      Apr 1997 - Feb 1999
      Research Technician

      Conducting research at the Department of Obstetrics and Gynaecology under the supervision of Professor Larry Chamley in the field of reproductive immunology (the role of antiphospholipid antibodies in causing stillbirths and recurrent miscarriages). Publications: Chamley L, Duncalf A, Konarkowska B, Mitchell M & Johnson P (1999). "Conformationally altered beta(2)-glycoprotein I is the antigen for anti-cardiolipin autoantibodies.", Clinical and experimental immunology. 115: 571-576.Chamley L, Konarkowska B, Duncalf A, Mitchell M & Johnson P (2001). Is interleukin-3 important in antiphospholipid antibody-mediated pregnancy failure?. Fertility and sterility. 76: 700-706. Show less

    • Douglas Pharmaceuticals

      May 2005 - Jul 2011
      Research And Development Officer

      Project management and new product development (formulation studies, manufacturing process development and validation, test method development and validation, cleaning validation/verification of equipment, technical writing, product packing and labelling for clinical studies, customer services, support of regulatory submissions to health authorities including the US FDA).

    • Douglas Pharmaceuticals Ltd.

      Aug 2011 - now

      Design and review of validation studies of quallity control test methods and new manufacturing/packing processes in a fully GMP compliant environment. Technical writing (test methods, validation protocols/reports and deviations/discrepancies, batch manufacturing records, GMP and GLP standard operating procedures). Coordination of technical transfers to other GMP sites. Training of validation personnel. Leading a team of 10 research scientists, executing validation tasks for new products.Validation of new test methods and new manufacturing processes.Validation of equipment cleaning methods for new products.Suitability verification of compendial methods.Transfer of test methods from raw material suppliers.

      • New Product Development Principal Scientist - Validation

        Jun 2018 - now

      • New Product Development Validation Team Leader

        Aug 2011 - May 2018

  • Licenses & Certifications