Talk to sales Try for Free
Giuditta Benincasa

Giuditta Benincasa

Followers of Giuditta Benincasa427 followers
location of Giuditta BenincasaCetara, Campania, Italy

Connect with Giuditta Benincasa to Send Message

Connect

Connect with Giuditta Benincasa to Send Message

Connect

  • Timeline

  • About me

    Researcher in Translational Medicine l Cardiology l Transplantation

  • Education

    • Università degli Studi di Napoli Federico II (UniNa) / University of Naples Federico II

      -
      Master I Level Food safety, nutrition and well-being

    • Università degli Studi di Napoli Federico II (UniNa) / University of Naples Federico II

      2014 - 2016
      Master's degree Molecular Biologist 110/110 cum laude

      Activities and Societies: Dissertion on "Alternative routes of metastasis of cutaneous melanoma". Performing immunohistochemistry methods, nucleic acid extraction (PCR, RT-PCR) and molecular hybridization (FISH, ISH) on paraffinized tissue sections from cancer patients.

    • University of Campania "Luigi Vanvitelli"

      2021 - 2024
      Specialization Board in Clinical Pathology and Clinical Biochemistry

      Training in performing virological assays for the identification of anti-HBV, -HCV, -HIV and Syphilis antibodies. Use of the Cobas E411 analyzer (Roche) on plasma samples from blood donors. Pre-transfusion tests (TYPE and SCREEN) for the determination of the ABO-Rh blood group through a slide agglutination system, direct and indirect Coombs tests for the compatibility between donor and recipient.

    • University of Campania "Luigi Vanvitelli"

      2018 - 2021
      Doctor of Philosophy - PhD Translational Medicine

      Activities and Societies: Member of the European Society of Cardiology (ESC) Member of the Council on Basic Cardiovascular Science (ESC) Member of the Working Group on Thrombosis Membership (ESC) Member of the Working Group of International Network Medicine Consortium, Channing Division of Network Medicine at Brigham and Women's Hospital Dissertation on "Pathogenic epigenetic-sensitive mechanisms in patients suffering from pulmonary arterial hypertension” in collaboration with Prof. Michele D'Alto, as internationally renowned cardiologist for the diagnosis and treatment of the rare disease pulmonary arterial hypertension at Monaldi Hospital (Naples, Italy). Technical skills: isolation of peripheral blood mononuclear cells by density gradient centrifugation; isolation of CD4+ and CD8+ T cells using magnetic beads; extraction… Show more Dissertation on "Pathogenic epigenetic-sensitive mechanisms in patients suffering from pulmonary arterial hypertension” in collaboration with Prof. Michele D'Alto, as internationally renowned cardiologist for the diagnosis and treatment of the rare disease pulmonary arterial hypertension at Monaldi Hospital (Naples, Italy). Technical skills: isolation of peripheral blood mononuclear cells by density gradient centrifugation; isolation of CD4+ and CD8+ T cells using magnetic beads; extraction and quantitation of genomic DNA from human cells and tissues; nucleic acid electrophoresis on agarose gel; extraction and quantitation of total RNA from cells and tissues and analysis of differential expression by qRT-PCR; extraction and quantification of proteins from cells and tissues, SDS-PAGE, Western blotting, ELISA; methylated DNA immunoprecipitation (MeDIP); evaluation of oxidative stress by lipid peroxidation test (MDA) on blood. Show less

  • Experience

    • University of Campania "Luigi Vanvitelli"

      Apr 2022 - Apr 2024

      Conducting research projects on the role of immune system in acute/chronic rejection events in kidney transplantation. Communicating scientific results at European Federation for Immunogenetics (EFI) Congress 2024.Performing molecular and cellular assays to determine HLA compatibility between donors and recipients in the context of kidney transplantion at U.O.C. of Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology (SIMT), Regional Reference Laboratory of Organ Transplant Immunology (LIT), A.O.U. “Luigi Vanvitelli”. Show less Conducting clinical research projects on mechanisms of epigenetic damage and cellular differentiation at the vascular level granted by Italian Ministry for Universities and Research (MUR) (ID Projects: PRIN 2017F8ZB89).Collaborating with a team of key opinion leaders in cardiology on the therapeutic role of sacubitril/valsartan in patients listed for heart transplantation and communicating results at the European Society of Cardiology (ESC) congress in Paris (2019) in quality of poster presenter.Conducting wet and dry laboratory techniques.Advising key opinion leaders in cardiology on newly available epidrugs and epigenetic biomarkers to plan and conduct multidisciplinary and innovative research programs.Serving as Member of the Working Group of the Network Medicine Institute and Global Alliance, Channing Division of Network Medicine at Brigham and Women's Hospital, Harvard Medical School.Serving as Academic Editor for Plos One journal (Impact factor 3.7) and as Guest Editor for Biomedicines (Impact factor 5) leading the Special Issue entitled "Epigenetics and Novel Opportunities for Precision Medicine and Personalized Therapy of Major Cardiovascular Diseases" (2023).Writing and publishing scientific papers on high-impact international journals (Scopus H-index 23, >50 publications, >1000 citations).Writing documentation of the application for an Ethics Committee opinion on a clinical trial.Writing proposal for grant applications and patents.Supervising of doctoral and graduate medical students.Serving as Reviewer of grant applications on heart transplantation for the National Science Centre (Poland). Serving as Invited Reviewer for Circulation Research, American Heart Journal, Clinical Epigenetics, Scientific Reports, Epigenetics, Cardiovascular Diabetology, Frontiers in Cardiovascular Medicine, Plos One and many other highly impacted journals. Show less

      • Researcher Fellow

        Apr 2023 - Apr 2024

      • Postdoctoral Researcher

        Apr 2022 - Mar 2023

    • Institut de Recerca Sant Pau

      Feb 2023 - Mar 2023
      Visiting Researcher

      Collaborating with Professor Lina Badimon's team on clinical research projects focusing on prognostic biomarkers in COVID-19. Learning to purify and characterize extracellular microvesicles from plasma samples of patients using flow cytometry.

  • Licenses & Certifications

    • Good Clinical Practice

      NIDA Clinical Trials Network

    • English

      ESOL (English School of London)

    • Grant Reviewer

      National Science Centre (Poland)

    • Primary and Advanced Courses in Applied Statistics and Research Methodology for Medical and Social Science and Practical Sessions with SPSS

      Necortex ETS Alta Formazione in Neuroscienze
      Jan 2022

    • ESC Congress

      European Society of Cardiology
      Jan 2020

    • Guest Editor

      Biomedicines MDPI
      Jan 2023

    • ESC Congress

      European Society of Cardiology
      Jan 2021

    • ESC Congress

      European Society of Cardiology
      Jan 2019

    • Young Investigator Award Heart Failure

      European Society of Cardiology
      Jan 2023

    • ESC Congress

      European Society of Cardiology
      Jan 2022

  • Honors & Awards

    • Awarded to Giuditta Benincasa
      Young Investigator Award Heart Failure European Society of Cardiology Aug 2023 I was honored to have been awarded by the prestigious ESC for the presentation of my research project entitled "Genome-wide DNA methylation profiling of circulating CD4+ T lymphocytes reveals potential diagnostic biomarkers in heart failure with preserved ejection fraction".
    • Awarded to Giuditta Benincasa
      Fellow Erasmus+ for Traineeship University of Campania "Luigi Vanvitelli" 2022
    • Awarded to Giuditta Benincasa
      Research Grant P.R.I.N. Italian Ministry of University and Research (MUR) 2022 Role: Component of PI Unit. Project: Epigenetic-sensitive mechanism, coding/non-coding genes, and paracrine mediators in multipotent stem cells from epicardial fat” funded by the MUR (PRIN2020XMLP45, PI: Prof. Claudio Napoli)
    • Awarded to Giuditta Benincasa
      Educational Travel Grant European Society of Cardiology Aug 2019 ESC Congress 2019 Paris
    • Awarded to Giuditta Benincasa
      Educational Travel Grant Trieste Next-Festival of Scientific Research Project Academy Trieste 2019