Alba Jimenez Pacheco

Experience

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  RCSI

  Aug 2011 - Jul 2012

  Research student

  Research student for the Prof. David Henshall’s Laboratory at the Department of Physiology and Medical Physics, Royall College of Surgeons in Ireland (RCSI) Dublin, Ireland. During my stay I was part of two projects ‘The role of bax during status epilepticus’ and ‘The role of miRNAs in the regulation of the P2X7 receptor’.

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  RCSI

  Nov 2012 - Jan 2015

  Profile: PhD student in Prof. David Henshall’s research group. The project was about “The Role of the ATP-gated P2X7 receptor in chronic epilepsy”. Part of the project was the trial of a new drug in collaboration with Janssen Research & Development, L.L.C., California, USA.Techniques:• Maintenance of GM mouse colonies (breeding and genotyping) • Laboratory animal handling (mouse brain dissection, transcardial perfusion) • Western blotting• qPCR and RT-PCR (mRNA) • DNA / RNA, microRNA extraction and purification • Intra-amygdala and intra-cerebroventricular surgeries for drug injections• Calcium microfluorimetry• EEG electrodes skull implantation and telemetry devices back implantation • Inmunohisto/cytochemistry• Synaptosomes isolation• Behavioural animal tests • Inmunoprecipitation • Optical and Confocal microscopy • Primary cultures• Methylation analyses with bisulfite sequencing techniques Visa mindre

  • Biology Demonstrator

    Feb 2014 - Jan 2015

  • PhD

    Sept 2011 - Jan 2015

  • Chemistry Demonstrator

    Nov 2012 - Jan 2014
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  Universidad Complutense de Madrid

  Sept 2013 - Jan 2014

  PhD Student

  PhD student in Prof. Maria Teresa Miras Portugal research group in the Departmet of Biochemistry and Molecular Biology, UCLM.

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  CABIMER

  Dec 2015 - now

  Postdoctoral Researcher

  Profile: Postdoctoral researcher in David Pozo’s research group in the Advanced Therapies in Neuroprotection & Immune Regulation Laboratory. Project:”Immune regulation of the purinergic receptor P2X7 involvement associated to Tr1 differentiation in Amyotrophic Lateral Sclerosis (ALS)”. The project is aimed to explore the feasibility of therapeutics interventions in ALS based on purinergic signalling manipulation in vitro and in vivo, in order to preferentially promote the differentiation of Tr1 or standard Treg cells. She also participates in a Clinical Assay with Lateral Sclerosis and Multiple Sclerosis Pacients. Visa mindre