Apoorva S.

Experience

• 

  Amity University Lucknow Campus

  May 2011 - Jul 2011

  Summer Intern

  Phytoremediation Potential of Eichornia crassipes in Effluent Treatment

• 

  Dr. Ram Manohar Lohia Institute of Medical Sciences

  Mar 2012 - Jun 2012

  Project Trainee

  Project: Immunohistochemical study of Her2/neu in breast cancer.The varied expression of HER2/neu expression was investigated in human tissues to understand its association with different stages and grades of tumor.• Learned handling of clinical specimens • Gained skills in histopathology including tissue fixation, sectioning, embedding, staining and result interpretation in terms of grading and scoring• Observed various instruments and techniques in molecular pathology, immunology and hematology lab during rotation period• Documented various protocols and prepared weekly presentations Show less

• 

  Anna University Chennai

  Sept 2013 - May 2014

  Project Fellow

  Therapeutic efficacy of Mito-Q on hypoxia induces apoptosis in tumor cells.The hypoxia resistant lymphoma cancer cells were successfully targeted by using synthetic antioxidant Mito-Q and its mechanism of action was studied. • Learned basic cell culture techniques including aseptic lab skills and handling and maintenance of cancer cell lines, fluorescence microscopy and calorimetry-based assays• Designed a mini hypoxic chamber with my team members to address the objectives of the work• Gained knowledge in cancer biology, and mitochondrial bioenergetics • Collaborated on another project which led to 1 scientific publication• Presented the results in an international conference Show less

• 

  Indian Institute of Technology, Kharagpur

  Dec 2014 - Jul 2023

  Graduate Student Researcher

  Title: Exploring metallo-curcumin nanoparticles as a treatment strategy for endometriosis• Synthesized metal-curcumin complexes (MCC) by conjugating curcumin, a plant-derived polyphenol, with 5 different trace metals, such as copper, zinc, iron, manganese and nickel followed by extensive spectroscopic characterization • Standardized protocol for MCC polymeric nanoparticle’s formulation by extensive optimization of several parameters followed by physical and chemical characterization including their fluorescence property• Carried out screening of MCC and nanoparticles in in vitro model comprising patient-derived cells by standardizing the protocol for isolation of cells from human tissues.• Investigated in-depth effect of MCC nanoparticles by evaluating their effect on cell viability, morphology, migration, invasion, oxidative stress and inflammation • Established cell culture lab in new space and trained junior lab members on biosafety protocols• Mentored 1 postgraduate and 2 undergraduate students for projects.• Assisted mentor in grant writing and peer-review leading to development of critical thinking skills• Initiated collaboration leading to 4 scientific publications and 2 in progress• Communicated research findings to clinicians and academicians in conferences and won 2 awards• Independently managed project from study design, data acquisition to data analysis• Managed laboratory functions including purchase of reagents and instruments, training lab assistant and assisting team members with their experiments Show less

• 

  Stanford University

  Mar 2024 - now

  Life Science Research Professional 2