Sara Braeckevelt, PhD

Experience

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  Charles University in Prague

  Feb 2015 - Sept 2015

  Research Student Erasmus +

  Erasmus plus program. Participation in research project "Development of new antibacterial active molecules".Synthesis, purification and biological evaluation of salicylanilides derivatives with potential anti-tuberculosis activity.

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  University of Pardubice

  Oct 2015 - Mar 2020

  PhD student

  PhD student in Organic and Technology Department in University of PardubiceResearch topic: Synthesis of advanced prostaglandin intermediates for technological applications- Dealing with multistep synthesis of prostaglandin intermediates starting from Corey aldehyde. - Asymmetric synthesis of propargyl alcohol present on alfaprostol moiety. Optimization of alkylation conditions using enantiomeric pure ligands.- Purification of organic compounds via chromatography column, crystalization and flash chromatography. - Literature research- Students supervison- Analitical skills: Interpretation of NMR, IR, elementary analysis, HPLC, Maldi-TOF Show less

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  Cayman Pharma s.r.o.

  Oct 2018 - Dec 2018

  Internship Trainee

  Internship in the R&D of Cayman Pharma, a company working in the synthesis of prostaglandins API. - Familiarization with the research and development of synthetic prostaglandin intermediates in a industrial level.- Synthesis of Corey alcohol from norbornadiene. Preliminary studies for future industrial application.- Synthesis and identification of process impurities in order to answer authority and internal inquiries.- Analytical skills: Interpretation of HPLC and LC-MS.

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  Comenius University in Bratislava

  Oct 2019 - Nov 2019

  Research Student Erasmus

  Research activity in the laboratory of Pharmaceutical Chemistry on Comenius University in Bratislava. Main tasks: Synthesis of carbonic anhydrases inhibitor with potential antiglaucoma activity.

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  APIGENEX s.r.o.

  Jan 2020 - Nov 2021

  Research Scientist - Peptide Chemist

  Synthesis, purification and quality evaluation of peptide molecules. During the year of 2020 I have helped to set up a new chemical facility in Pardubice aiming the synthesis and purification of peptide molecules.- Use of automated peptide synthesizer such as SymphonyX and LibertyBlue.- Manual modifications of peptides such as ortogonal deprotections, formation of cyclic peptides, alkylations, manual couplings, acetilations, etc.- Analytical skills: UPLC, HPLC and LC-MS use on a daily basis. Daily interaction with Empower and Masslynx Softwares. - Purification of peptides using RP-HPLC. - Isolation of Peptides using Lyophilization/freeze drying. Show less

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  Biosynth

  Jan 2022 - Feb 2024

  As a Product Specialist, I engage directly with customers on a daily basis, serving as a vital link between Biosynth and our customers. Central to my role is comprehending and supporting customer needs while identifying the optimal solutions Biosynth can offer. I am accountable for efficiently managing order intake for complex peptides (R&D) and peptides prepared under GMP (Good Manufacturing Practice). From initial request to final delivery, I take charge of seamless communication with customers, ensuring a smooth and satisfying experience throughout the entire process. Show less

  • Business Line Manager

    May 2023 - Feb 2024

  • Product Specialist Complex & NCE Peptides

    Feb 2022 - May 2023

  • Product Specialist Complex Peptides

    Jan 2022 - Feb 2022
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  Thermo Fisher Scientific

  Feb 2024 - now

  Technical Sales Specialist - Production Chemicals and Services

  Responsible for the territory development of two business lines: Production Chemicals and Services (including cGMP chemicals) and Process Liquids (including buffer solutions). Collaborate with account managers and field specialists to identify, develop, and close deals with new and existing customers. Assess customer needs and guide them through the negotiation process, working with internal teams to ensure the feasibility and quality of Thermo Fisher services. Identify additional business opportunities and cross-selling potential within the Thermo Fisher portfolio. Show less