
Pia Rivetti Di Val Cervo, PhD
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About me
Dirigente Biologo
Education

Lycée Chateaubriand
-
Farminerva
2019 - 2019Corso di formazione valido ai fini del DM 15/11/2011 Sperimentazione clinica e Good Clinical Practice pass• 40 hours training course on the “definition of the minimal requirements for Contract Research Organizations in medical clinical trials”, in compliance with the Italian Ministerial Order 15-11-2011.• Course on “Clinical Trials and Good Clinical Practice” • GCP,GMP, GVP• Advanced Therapy Medicinal Products

Università di Roma Tor Vergata
2006 - 2011Doctor of Philosophy - PhD Biochemistry and Molecular BiologyThe aim of my PhD project was to evaluate the role of microRNAs cellular mechanisms such as differentiation and senescence in skin biology. We analysed the relationship between miR203 and p63, an important transcription factor for skin development and maintenance of the differentiating stratified epithelium of the epidermis. Subsequently, I have been working on the role of a discrete set of microRNAs, identified by MicroArray, in the regulation of replicative senescence pathways in primary… Show more The aim of my PhD project was to evaluate the role of microRNAs cellular mechanisms such as differentiation and senescence in skin biology. We analysed the relationship between miR203 and p63, an important transcription factor for skin development and maintenance of the differentiating stratified epithelium of the epidermis. Subsequently, I have been working on the role of a discrete set of microRNAs, identified by MicroArray, in the regulation of replicative senescence pathways in primary human keratinocytes. In particular we have identified a regulation pathway involving p63, miRs 138, 130 and 181 and SirT1. Show less

Sapienza Università di Roma
2001 - 2004Laurea Triennale BiologiaDuring the experimental work for my thesis, done at the Department of Biochemical Sciences "A. Rossi Fanelli" of the University La Sapienza of Rome, with the supervision of prof. M. Eugenia Schininà, I have undertaken the structural analysis of M. leprae’s truncated haemoglobin O, aiming for the identification of the two residues of tyrosine that would lead to the biphenyl linkage. This work has been carried out in collaboration with prof. P. Visca’s group at the Dept.of Biology and… Show more During the experimental work for my thesis, done at the Department of Biochemical Sciences "A. Rossi Fanelli" of the University La Sapienza of Rome, with the supervision of prof. M. Eugenia Schininà, I have undertaken the structural analysis of M. leprae’s truncated haemoglobin O, aiming for the identification of the two residues of tyrosine that would lead to the biphenyl linkage. This work has been carried out in collaboration with prof. P. Visca’s group at the Dept.of Biology and Electronic Microscopy Laboratory of the Università degli Studi di “Roma Tre”. Show less

Sapienza Università di Roma
2004 - 2006Laurea Specalistica Biologia Molecolare e BiochimicaFor my thesis I did experimental work as graduate student at the Department of Biochemical Sciences "A. Rossi Fanelli" of the University La Sapienza of Rome (Italy), supervisor prof. M. Eugenia Schininà.I wanted to expand my knowledge on post synthetic modification on polypeptides and their involvement in protein structure and function. I have focused on the relationship between redox state and biological activity of human neuroglobin whose function seems to be modulated by the presence of… Show more For my thesis I did experimental work as graduate student at the Department of Biochemical Sciences "A. Rossi Fanelli" of the University La Sapienza of Rome (Italy), supervisor prof. M. Eugenia Schininà.I wanted to expand my knowledge on post synthetic modification on polypeptides and their involvement in protein structure and function. I have focused on the relationship between redox state and biological activity of human neuroglobin whose function seems to be modulated by the presence of a disulfide bond and a free cystein whose role hasn’t been clarified yet. Show less
Experience

Freelance
Jun 2002 - Aug 2006Independent TranslatorFor a few years, as I was studying at the University, I worked as a translator for ENAPRA, at the Italian Ministry of Agriculture.I was translating Italian into English and into French for the European project Agrisavoir.
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Paris-Sud University (Paris XI)
Sept 2005 - Mar 2006Visiting StudentStage as graduate student at Biochemistry, Molecular and Cellular Biophysics Institute (IBBMC) of the National Scientific Research Centre (CNRS), at the University Paris-Sud 11 in Orsay (France), supervisor prof. Pierre Le Maréchal.During my last year as a graduate student in the University of Rome “La Sapienza”, I have decided to do a stage in a foreign country in order to learn new research techniques and approaches. I worked for a six months stage in prof. Pierre Le Maréchal’s group, working in the chemistry of proteins field. During this period I identified the targets of the Thioredoxin/Thioredoxin Reductase system in Saccharomyces cerevisiae using a proteomic strategy coupled to a differential labelling technique. Show less

Medical Research Council
Jul 2008 - Aug 2008Visiting PHD StudentDuring my PhD I went to collaborate with prof. Melino’s group in Leicester in order to learn neurobiology techniques and to unravel the role of microRNAs involved in brain morphogenesis and cortical neuron differentiation in a p73 null background.

EMBO - excellence in life sciences
Jan 2012 - Dec 2013EMBO FellowAs EMBO Fellow, I have managed a research project from the initial design phase through its implementation and results dissemination. The project aimed at exploring a new avenue for cell replacement therapy for Parkinson's Disease. In particular we decided to reprogram glial cells resident in the brain into neurons, to replace the dopaminergic neurons killed by the disease's progression. To achieve this goal I have modified and optimized a new protocol for direct conversion in vitro and in vivo. Show less

Karolinska Institutet
Nov 2014 - May 2017As research fellow (subsidized by the Swedish Research Council, the EMBO and the Karolinska Institute), my tasks were managing and implementing research projects from the initial design phase to completion, in addition to results dissemination, reporting and publication. During my post-doc I developed a new protocol for in vivo conversion of astrocytes into dopaminergic neurons, as a new cell replacement approach for Parkinson’s Disease. In addition I was also involved in the following:• Student supervision.• Public speaking at conferences and seminars.• Teaching to students of the Medicine, and Biomedicine courses at the University of Malaga.• Teaching to students of the Medicine, Dentistry and biomedicine courses at Karolinska Institutet. Show less
Research Fellow sponsored by EMBO and the Swedish Research Council
Jan 2011 - May 2017Coordinator of the MBB Virus facility
Nov 2014 - Dec 2016

Marie Curie Fellows Association
May 2017 - Oct 2019Marie Curie FellowAs Post-doctoral fellow sponsored by the Marie Sklodowska-Curie Actions Individual Fellowships program of the European Commission, I have managed a research project from the initial design phase to implementation for the generation of a disease modelling platform based on directly-reprogrammed medium spiny neurons to screen new therapeutic compounds against Huntington’s Disease.

Università degli Studi di Milano
May 2017 - Nov 2021Senior Post-Doctoral ScientistAs senior post-doctoral researcher, my tasks are focused on communication and publishing as much as on research and development, in particular I focus on writing and editing of scientific documents for publication in high impact factor peer-reviewed scientific journals and dissemination. My work in the research and development branch of the laboratory encompasses managing research projects from the project design phase to the implementation phase and subsequent reporting. I am also involved in budget evaluation and project sustainability as well student training, teaching and speaking at conferences. Show less

LaSpes
Jan 2018 - Dec 2024Coordinator of the Scientific CommitteeCoordinator and Grant evaluator - Research projects on neurological aspects of Wiskott-Aldrich Syndrome.

Elsevier
Nov 2021 - Dec 2021Associate Scientific Editor
AIFA Agenzia Italiana del farmaco
Dec 2021 - nowDirigente biologoHealth Technology Assessment

European Commission
Aug 2024 - nowRepresentative - Joint Scientific Consultation Subgroup
Licenses & Certifications

Iscrizione all'Ordine dei Biologi
Ordine Nazionale dei BiologiFeb 2019
Honors & Awards
- Awarded to Pia Rivetti Di Val Cervo, PhDISSCR travel award - Jun 2016
- Awarded to Pia Rivetti Di Val Cervo, PhDPhD scholarship from the Italian Ministry of Education. - Nov 2006
- Awarded to Pia Rivetti Di Val Cervo, PhDScolarship for Master Thesis abroad from the Faculty of Sciences, University Sapienza of Rome - Sep 2004
Languages
- itItaliano
- frFrancese
- inInglese
- svSvedese
- spSpagnolo
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