Emma Young

Experience

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  Iarnród Éireann Irish Rail

  May 2007 - Sept 2009

  Construction Administrator

  Summer position for three consecutive years during second level and undergraduate education 2007, 2008, 2009. General office administration in a large and very busy capital project, including organising meetings, conferences, making travel arrangements, hotel reservations, foreign travel and preparation of itineraries. Document Control using Primavera Expedition for time sensitive ‘sent’ and ‘received’ correspondence involving three large contractors. Process weekly and monthly staff timesheets; record staff annual and sick leave. Record confidential minutes of meetings, prepare, distribute and follow up on "action items". Deputising for office manager in her absence. General secretarial duties, including use of company vehicle to carry out project site office administration occasionally. Show less

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  ESB

  May 2010 - Sept 2011

  Administrator

  Summer position for two consecutive summers during undergraduate education 2010 and 2011Preparing quotations for new domestic connections Receiving, processing and approving electrical bill payments by post. Responsibility for handling cash payments and preparing lodgements Collections: Contacting customers regarding payments in arrears.

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  St. James's Hospital Dublin

  Aug 2010 - Apr 2011

  Medical Laboratory Scientist Student

  Clinical laboratory placement as part of Bachelor of Science (Hons) Biomedical Science degree.Specimen reception. Training in routine laboratory testing; observe specialist tests in reference laboratory. Troubleshooting machines. Perform manual test where automated method was not available. Shadowing Medical Scientist in authorisation of results. Learning quality control and quality assurance policies. Reviewing standard operating procedures (SOP) in each discipline. Show less

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  Monsoon Accessorize

  Apr 2011 - Oct 2011

  Sales Assistant

  Welcoming customers into the store. Assisting with shopping, helping to accessorise outfits.Selling, restocking and merchandising.Processing cash and card payments and handling returns.Cleaning, maintaining and organising the store.

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  Creganna Medical

  Jun 2012 - Sept 2012

  Market Researcher

  Research into the clinical background of medical devices. Documenting the procedure, identifying related products in the procedure. Building profiles of existing products on the market. Mapping the test methods used to demonstrate performance. Researching the market for innovations in development.

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  Uppsala University

  Apr 2013 - Feb 2018

  Recurrent Genetic Mutations in Lymphoid MalignanciesPaper I: We screened 565 subset cases of chronic lymphocytic leukemia (CLL), preferentially assigned to clinically aggressive subsets, and confirm the SF3B1 mutational bias in subset #2 (45%), but also report on similarly marked enrichment in subset #3 (46%). In contrast, NOTCH1 mutations were predominantly detected in subsets #1, #8, #59 and #99 (22-34%). This data further highlights a subset-biased acquisition of genetic mutations in the pathogenesis of at least certain subsets.Paper II: We screened 1460 patients with various lymphoid malignancies for NFKBIE deletions and reported enrichment in classical Hodgkin lymphoma (27%) and primary mediastinal B-cell lymphoma (PMBL) (23%). NFKBIE-deleted PMBL cases had higher rates of chemorefractoriness and inferior overall survival. NFKBIE-deletion status remained an independent prognostic marker in multivariate analysis.Aberrant NF-κB signaling due to a deletion within the NFKBIE gene previously reported in CLL warranted extended investigation in other lymphoid malignancies. Therefore, inPaper III: We screened 2403 CLL patients for mutations in EGR2. An overall mutational frequency of 3.8% was reported and EGR2 mutations were associated with younger age, advanced stage and del(11q). EGR2 mutational status remained an independent marker of poor outcome in multivariate analysis, both in the screening and validation cohorts. EGR2 mutations were recently reported in advanced stage CLL patients; thus, inPaper IV: We used WGS in 70 CLL cases assigned to poor-prognostic subsets #1 and #2 and indolent subset #4, the results revealed a similar skewing of SF3B1 mutations in subset #2 and NOTCH1 mutations in subset #1 to that reported in Paper I. Additionally, an increased frequency of the recently proposed CLL driver gene RPS15 was observed in subset #1. Finally, novel non-coding mutational biases were detected in both subset #1 and #2 that warrant further investigation. Show less

  • Postdoctoral Researcher

    Jun 2017 - Feb 2018

  • PhD Student

    Apr 2013 - May 2017
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  Karolinska Institutet

  Mar 2018 - Jan 2019

  Postdoctoral Researcher
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  Genuity Science

  Feb 2019 - Aug 2020

  Clinical Research Scientist

  Accountabilities and Duties• Oncology, immunology and rheumatology responsible clinical research scientist.• Development of disease specific documentation including REC applications, life-style questionnaires and case report forms.• Competent scientific writing and editing for research, industry and lay publications.• Passionate and engaging presentation design and delivery for research, industry and lay audiences.• Collaboration on projects within multidisciplinary teams across various departments including bioinformatics, clinical partnerships, programme management, site monitoring, IT, quality, data management, legal and compliance.• Cultivate relationships with scientific and medical key opinion leaders in relevant disease related fields.• Analysis of participants raw phenotypic data and downstream analysis of genomic data.• Mentorship and supervision of interns and new research staff.• Contribute to the identification of new potential disease cohorts for development.• Identify and complete appropriate continuing professional development (CPD) courses and training that align with the companies’ goals.• Fire warden and evacuation chair trained. Show less

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  Rotunda Hospital

  Aug 2020 - Aug 2021

  Medical Laboratory Scientist
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  St. James's Hospital Dublin

  Aug 2021 - now

  Medical Laboratory Scientist

  Staff grade medical laboratory scientist in Haematology cell counting and morphology lab