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Felipe Freitas De Castro, Ph.D.

Felipe Freitas De Castro, Ph.D.

Diretor Administrativo Financeiro

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  • Timeline

  • About me

    Especialista em Genética Médica | Diagnóstico Molecular | NGS | CRISPR | Pesquisa Translacional

  • Education

    • Faculdade de Minas

      2005 - 2007
      FAMINAS Farmácia

    • Universidade de São Paulo

      2012 - 2017
      Doctor of Philosophy - PhD Cellular and Molecular Biology

      Activities and Societies: - multiple characterization of G418 stress in Leishmania major - classical genetic manipulation of Leishmania parasites - profiled of coding and noncoding RNAs from Leishmania parasites by deep sequencing (Illumina) - Pull-down adaptation based on S1m aptamer RNA tag for Leishmania cells This method allows to determinate experimentally RNA binding proteins on a global scale - student-monitor of Biomolecules, Cell Biology and Biostructures classes

    • Universidade Federal de Viçosa

      2007 - 2012
      Bachelor of Science in Biochemistry Biochemistry and Molecular Biology

      Activities and Societies: - NTPDase-1 from Leishmania infantum and Trypanosoma cruzi enzymatic characterization, immunolocation and study of its role in "in vitro" infection - student-monitor of Biochemistry Laboratory I classes - administrative and financial director/presidency advisor of Tecnomol company

  • Experience

    • Tecnomol - Empresa Júnior de Consultoria em Bioquímica

      Aug 2008 - Dec 2011
      Diretor Administrativo Financeiro

      Diretor Administrativo Financeiro da Associação civil de Bioquímica de agosto de 2008 a 2011.

    • Universidade Federal de Viçosa

      Apr 2009 - Jan 2012

      Project: Immunolocalization and evaluation of the role of NTPDase-1 from Trypanosoma cruzi in cell adhesion. Lab. de Bioquímica I (BQI 101), do Departamento de Bioquímica da Universidade Federal de Viçosa.

      • Iniciação Científica

        Mar 2008 - Jan 2012

      • Monitor da Disciplina Lab. de Bioquímica I

        Apr 2009 - Dec 2009

    • Faculdade de Medicina de Ribeirão Preto (FMRP) da USP

      Feb 2012 - Sept 2017
      PHD Fellow | Cellular and Molecular Biology

      Project: Investigation of noncoding RNAs involved in gene expression regulation in Leishmania.

    • Hemocentro de Ribeirao Preto

      Jan 2018 - Jan 2019
      Postdoctoral Research Fellow | Human Molecular Genetics

      Project: Correction of pathogenic variants in COL1A1 / COL1A2 genes in mesenchymal stromal cells of Osteogenesis Imperfecta patients using CRISPR/Cas9 technology

    • Faculdade de Medicina de Ribeirão Preto (FMRP) da USP

      Jan 2019 - Nov 2021
      Postdoctoral Research Fellow | Molecular Biology

      Projects: 1) Biogenesis and mechanism of action of ODD3, a non-coding RNA that acts in the control of gene expression in Leishmania.2)Use of CRISPR/Cas9 technology to study the role of extracellular vesicles in the modulation of the inflammasome in macrophages infected by Leishmania.

    • Hospital das Clínicas da Faculdade de Medicina da USP

      Nov 2021 - now
      Postdoctoral Research Fellow | Human Molecular Genetics

      Project: Whole-exome sequencing for the investigation of novel genetic causes of metastatic pheochromocytomas and paragangliomas.

  • Licenses & Certifications

    • Certificado de Participação - Projeto Genomas Raros - Workshop

      Even3
      Dec 2022
      View certificate certificate