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Ahmed Metwaly

Ahmed Metwaly

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location of Ahmed MetwalyCairo, Egypt

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  • Timeline

  • About me

    Associate Professor of Pharmacy at Al-Azhar University, Cairo, Egypt. One of the most 2% world's impacting scientists.

  • Education

    • Al-Azhar University

      1996 - 2001
      Bachelor's Degree Pharmacy Excellent with grade of honor

    • Al-Azhar University

      2003 - 2009
      Master's Degree Natural Products Chemistry and Pharmacognosy

    • Al-Azhar University

      2009 - 2014
      Doctorate Degree Natural Products Chemistry and Pharmacognosy

    • University of Mississippi

      2012 - 2014
      Phytochemistry

      My Ph. D. subject was the isolation of bioactive secondary metabolites from endophytic fungi. The endophytic fungus Alternaria phragmospora (the most potent antimalarial) was subjected to different chromatographic techniques resulting in the isolation of five new (2, 4, 6, 7, 9) and four known (1, 3, 5, 8) isocoumarin derivatives as well as four new (12-15) and two known (16, 17) α-pyrone derivatives. Nigrosphaerin A, a new isochromene derivative (18) was isolated from the endophytic fungus… Show more My Ph. D. subject was the isolation of bioactive secondary metabolites from endophytic fungi. The endophytic fungus Alternaria phragmospora (the most potent antimalarial) was subjected to different chromatographic techniques resulting in the isolation of five new (2, 4, 6, 7, 9) and four known (1, 3, 5, 8) isocoumarin derivatives as well as four new (12-15) and two known (16, 17) α-pyrone derivatives. Nigrosphaerin A, a new isochromene derivative (18) was isolated from the endophytic fungus Nigrospora sphaerica in addition to nineteen known compounds (19-37). The isolated compounds were chemically identified using 1D NMR (1H, 13C, DEPT135) and 2D NMR (COSY, HMQC, HMBC), HR-ESI-MS as well as X-ray for some crystalline compounds. Compounds 1 and 10 showed potent antimalarial activities against Plasmodium falciparum D6 clone with IC50 values of 0.3 and 0.8 μM, respectively, and W2 clone with IC50 values of 0.2 and 0.8 μM, respectively. Show less

  • Experience

    • Al-Azhar University

      Aug 2003 - Jan 2012

      Teaching practical courses about phytochemistry and pharmacognosy Teaching practical courses about phytochemistry and pharmacognosy

      • Lecturer assistant

        May 2009 - Jan 2012

      • Demonstrator

        Aug 2003 - May 2009

    • University of Mississippi School of Pharmacy

      Jan 2012 - Feb 2014
      Visiting Scholar

      My work focused on the isolation and characterization of active secondary metabolites from endophytic fungi, and plants with significant activity against Methicillin-Resistant Staphylococcus aureus (MRSA), E-Coli, some fungi, malaria, and leishmania. I had handled some traditional and sophisticated isolation techniques as well as analytical instruments such as Biotage, Chromatotron, SPE, GC/MS, HPLC, HPTLC, NMR, LC/MS, ECD, UV, and IR.

    • Nahda University - NUB

      Sept 2014 - Aug 2015
      Lecturer

    • Al-Azhar University

      Sept 2014 - now

      I was the head of training committee in the faculty. I was teaching a vital course for postgraduates and scientific researchers about using Nuclear Magnetic Resonance (NMR) to identify the chemical structure of the isolated secondary metabolites as well as the synthesized compounds. I was teaching several courses for undergraduate students including Tissue culture, Phytochemistry, Pharmacognosy, Botany in addition to advanced chromatographic and analytical techniques (HPLC, HPTLC, GC, UPLC, and LC-Ms) as well as advanced spectrometric techniques (Ms, IR, UV, and NMR). Show less

      • Associate Professor of Pharmacy

        Jun 2020 - now

      • Assistant professor

        Sept 2014 - May 2020

    • Liaoning University of Traditional Chinese Medicine

      Jun 2018 - Jun 2019
      Senior Research Fellow

      I worked on three different projects;1. A project focusing on black ginseng2. A project focusing on the traditional antidiabetic herbal formula YTK.3. A project focusing on the isolation and characterization of active secondary metabolites from airial parts of Tagetes patula.

    • City of Scientific Research and Technological Applications SRTA-City

      Nov 2021 - Nov 2023
      Associate Professor

      Doing scientific research in the field of drug discovery

  • Licenses & Certifications

    • Ph D

      Al-Azhar University / University of Mississippi
      May 2014

  • Honors & Awards

    • Awarded to Ahmed Metwaly
      Training honor Faculty of pharmacy, Al-Azhar University December 1, 2021
    • Awarded to Ahmed Metwaly
      Talented Young Scientist (TYSP) Chinese Academy of science Jun 2018
    • Awarded to Ahmed Metwaly
      One of the best cited ten manuscripts in Journal of Phytoochemistry letters Journal of Phytoochemistry letters 2015 One of the best cited ten manuscripts in Journal of Phytoochemistry letters for the publication (Nigrosphaerin A a new isochromene derivative from the endophytic fungus Nigrospora sphaerica)
    • Awarded to Ahmed Metwaly
      Joint supervision scholarship Egyptian government Jan 2012