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Anh-Thu Lam, Ph.D.

Anh-Thu Lam, Ph.D.

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  • Timeline

  • About me

    Patent Law Technical Specialist

  • Education

    • Hanover High School

      2003 - 2007
      Highschool Diploma

      Activities and Societies: National Honor Society

    • University of Vermont

      2007 - 2011
      Bachelor's Degree Spanish

      Activities and Societies: Sigma Delta Pi - La Sociedad Nacional Honoraria Hispánica ; The National Society of Collegiate Scholars

    • The Johns Hopkins University School of Medicine

      2014 - 2019
      Doctor of Philosophy (Ph.D.) Human Genetics and Molecular Biology

      Cystic fibrosis (CF) is a life-shortening genetic disorder that primarily affects the lungs and digestive system. CF affects over 30,000 individuals in the United States and more than 70,000 individuals worldwide. The gene responsible for CF (CFTR) was identified in 1989. However, phenotypic variation in a monogenic disorder, such as CF, can be attributed to several sources, including different mutations in the disease-causing gene, genetic modifiers, environmental factors, and interactions… Show more Cystic fibrosis (CF) is a life-shortening genetic disorder that primarily affects the lungs and digestive system. CF affects over 30,000 individuals in the United States and more than 70,000 individuals worldwide. The gene responsible for CF (CFTR) was identified in 1989. However, phenotypic variation in a monogenic disorder, such as CF, can be attributed to several sources, including different mutations in the disease-causing gene, genetic modifiers, environmental factors, and interactions among and between any of these sources. It has become increasingly evident that modifier genes play substantial roles in determining the severity of disease, particularly lung disease. Identifying and characterizing these modifiers is crucial in devising therapies and other interventions to decrease the morbidity and mortality associated with this disorder. Show less

    • University of Vermont

      2007 - 2011
      Bachelor's Degree Biochemistry

      Activities and Societies: UVM Taekwondo Club, MEDLIFE University of Vermont Honor College Class of 2011

  • Experience

    • University of Vermont

      Jun 2010 - Dec 2011

      Study focused on the phospho-regulation of Collapsin Response Mediator Proteins (CRMPs), key effectors downstream of neuronal guidance cues. Mentor: Bryan A. Ballif, PhDhttps://www.uvm.edu/~bballif/ Study focused on the psychological effect and stigmatism of men and women infected with the Human Immunodeficiency Virus. Mentor: Sondra Elice Solomon, PhD

      • Research Assistant

        Aug 2008 - Dec 2011

      • Student Researcher

        Jun 2010 - Aug 2011

    • Boston Children's Hospital

      Jun 2012 - May 2014
      Research Technician

      Research focuses on genetic analysis of pathogenic variants relating to cerebral cortical development and disorders of the human brain in consanguineous and non-consanguineous families. Mentor: Christopher A. Walsh, MD, PhDwalshlab.org

    • Johns Hopkins Medicine

      Aug 2014 - Jun 2021

      Studies revolved around modeling the effects of disease-associated variants in schizophrenia using CRISPR technologies to introduce the variants of interest into iPSCs Doctoral work focused on how noncoding variation in regulatory sequences may contribute to phenotype variation and disease risk/presentation in the context of cystic fibrosishttps://igm.jhmi.edu/human-genetics-students

      • Postdoctoral Research Fellow

        May 2019 - Jun 2021

      • Doctoral Candidate

        Aug 2014 - May 2019

    • DRT Strategies

      Jun 2021 - Apr 2023
      Expert Consultant - Clinical Data Scientist

      • Work as a clinical data scientist in support of the FDA Center for Drug Evaluation and Research• Lead meetings to communicate with clinical review teams to develop Safety Data Review Plans (SDRPs) for INDs/NDAs submitted to the Office of New Drugs• Conduct comprehensive clinical safety analyses using R and provide safety tables and figures to clinical review teams• Experience with JMP/JMP Clinical

    • Sterne, Kessler, Goldstein & Fox

      May 2023 - now
      Technical Specialist

  • Licenses & Certifications

    • First Aid and CPR

      Northern New England-VT
      Mar 2010

  • Volunteer Experience

    • Co-Chair

      Issued by 2022 Gordon Research Seminar on Human Genetic Variation and Disease on Jun 2018
      2022 Gordon Research Seminar on Human Genetic Variation and DiseaseAssociated with Anh-Thu Lam, Ph.D.

    • Data Specialist

      Issued by Beth Israel Deaconess Medical Center on Apr 2012
      Beth Israel Deaconess Medical CenterAssociated with Anh-Thu Lam, Ph.D.

    • Tutor

      Issued by Boston Children's Hospital on Aug 2012
      Boston Children's HospitalAssociated with Anh-Thu Lam, Ph.D.

    • Tutor

      Issued by Boys&Girls Club of Burlington on May 2010
      Boys&Girls Club of BurlingtonAssociated with Anh-Thu Lam, Ph.D.

    • Volunteer

      Issued by Medicine Education Development for Low Income Families Everywhere on Dec 2010
      Medicine Education Development for Low Income Families EverywhereAssociated with Anh-Thu Lam, Ph.D.

    • Hospital Volunteer

      Issued by Fletcher Allen Health Care on Jun 2009
      Fletcher Allen Health CareAssociated with Anh-Thu Lam, Ph.D.

    • Emergency Room Intern

      Issued by Quincy Medical Center on Jun 2006
      Quincy Medical CenterAssociated with Anh-Thu Lam, Ph.D.

    • Hospital Volunteer

      Issued by Caritas Carney Hospital, Boston MA on Jun 2005
      Caritas Carney Hospital, Boston MAAssociated with Anh-Thu Lam, Ph.D.