Jonatan U. Fangel

Experience

• 

  Lundbeck

  Jan 2008 - Jan 2009

  Student assistent
• 

  University of Copenhagen

  Sept 2010 - Oct 2015

  Project: Investigate evolutionary trends and their influence on cell wall composition and architecture in plants. Responsibilities:• Main responsible for setting up, running and troubleshooting microarray facility as well as training of new users.• Designed and managed projects and experiments for 10+ international collaborations.• Created extensive plant polysaccharide library covering the diversity of the plant kingdom for evolutionary research.• Solved the challenge of generating glycomic profiles for large sample sets.• Data management and analysis: Implemented multivariate data analysis for extracted glycan microarray data.• Invited speaker for 2 international conferences in Belgium and Spain.• Teaching Assistant, Plant Polysaccharides: Biology, Structure and Applications. Assisting in course development, and lecturing.New methodologies: Multivariate data analysis, High-performance liquid chromatography Show less The focus of the PhD was to develop, optimise and implement high throughput technologies for investigating plant cell wall polymers and probesThesis: ‘Advanced technologies for plant cell wall evolution’Responsibilities: • Set up a new microarray lab and adapted existing procedures to new equipment• Established an immuno-microarray based platform enabling fast, consistent and high quality glycomic analysis (mapping the complete polysaccharide material within an organism).• Created a new type of carbohydrate microarray for characterizing molecular probes such as monoclonal antibodies and carbohydrate binding modules.• Developed a new high throughput screening method for carbohydrate active enzymes.• Developed an integrated ‘omics approach for understanding cell wall evolution and diversity.• Shared knowledge at several scientific conferences (four oral presentations) and seminars.• Collaborated on 9 publications based on the research carried out.• Trained and mentored several MSc and PhD students.• Taught and supervised at the University of Copenhagen education program.New methodologies: Defined glycan microarrays; Extracted glycan microarrays; Enzyme characterisation; Epitope deletion; Immunocytochemistry; General microscopy - embedding and sectioning; Immunofluorescence; Bioinformatics: BLAST and alignment methods, sequence analysis, phylogenetic analyses, transcriptome/gene expression data analyses; Monosaccharide composition analysis. Show less

  • Postdoctoral Researcher

    Nov 2013 - Oct 2015

  • PHD Student

    Sept 2010 - Nov 2013
• 

  Carlsberg Group

  Oct 2015 - Feb 2018

  Project: Incorporate novel high-throughput technology for tracking in detail the fate of polysaccharides and enzyme activities throughout the brewing processResponsibilities:• Implemented high-throughput screening procedures for analysis of every key step during the brewing process.• Defined polysaccharide markers related to brewing process, raw materials and enzyme usage.• Developed grain pre-treatments for inactivation of enzyme activity and increasing polysaccharide yield.• Provided support for brewing technology and ingredient groups.• Provided quality control of beer and other products.• Detailed comparative analysis of beta-glucan detection assays.New methodologies: Ultra performance liquid chromatography, Enzymatic assays Show less

  • Research Scientist

    Oct 2017 - Feb 2018

  • Postdoctoral Researcher

    Oct 2015 - Oct 2017
• 

  Novozymes

  Mar 2018 - Jan 2024

  • EA to the EVP of R&D

    Feb 2023 - Jan 2024

  • Senior Scientist

    Jul 2021 - Feb 2023

  • Research Scientist

    Mar 2018 - Jun 2021
• 

  Novonesis

  Feb 2024 - now

  • R&D Strategy & Coordination Manager

    May 2024 - now

  • EA to the EVP of R&D

    Feb 2024 - Jun 2024