Franck S.

Franck S.

Industrial Intern, Medicinal Chemistry

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  • Timeline

  • About me

    Director, Project Management

  • Education

    • ENSCM

      2002 - 2005
      Master of Science (MSc) Organic Chemistry
    • Lycée Charlemagne/ENSCM

      1999 - 2002
      Bachelor of Science (BSc) Chemistry
    • Lycee Helene Boucher

      1996 - 1999
      Baccalaureat S Mathematics, Physics, Chemistry, Biology
    • University of Oxford

      2004 - 2007
      DPhil Organic Chemistry

      -Development of monoclonal antibody-mediated retro-aldolisation kinetic resolution of beta-hydroxyynones combined with cross-metathesis.-Development of Direct Organocatalytic Aldol Addition of Ynones to aromatic Aldehydes -Synthetic Applications: 6-endo-dig Palladium-mediated oxidative Domino Wacker-Heck cyclisation, 5-exo-dig phosphine-mediated cyclisation, 6-endo-dig Gold-Selectfluor mediated cyclisation/fluorination.-Studies towards total synthesis of natural product… Show more -Development of monoclonal antibody-mediated retro-aldolisation kinetic resolution of beta-hydroxyynones combined with cross-metathesis.-Development of Direct Organocatalytic Aldol Addition of Ynones to aromatic Aldehydes -Synthetic Applications: 6-endo-dig Palladium-mediated oxidative Domino Wacker-Heck cyclisation, 5-exo-dig phosphine-mediated cyclisation, 6-endo-dig Gold-Selectfluor mediated cyclisation/fluorination.-Studies towards total synthesis of natural product (goniothalesdiol).-Supervision of summer, undergraduate (Part II) and DPhil students. Demonstration in teaching laboratories. Show less

  • Experience

    • GlaxoSmithKline

      Sept 2003 - Aug 2004
      Industrial Intern, Medicinal Chemistry

      -Voluntary 12-month industrial placement. -Medicinal Chemistry: parallel organic synthesis (microwave-assisted Suzuki reactions), use of varied purification methods (SPE, Biotage, MDAP) and analysis of structure-activity-relationship of synthesised biologically active compounds.

    • Karus Therapeutics

      Oct 2007 - Dec 2017

      -Experience in leading medicinal chemistry projects in semi-virtual environment: Hit toLead, Lead Optimisation, Development Candidates.-Direct contribution to 2 Clinical candidates nominations and their successful IND filings.-Experience of Process Development for Tox and Clinical purposes-Design small molecules in Inflammation and Cancer disease settings.-CRO Outsourcing (Chemistry, DMPK, Tox, Efficacy)-Research Associate direct line management.-Project Manager (Phase I Trial): liaising with various teams (CMC, Pre-clinical, Regulatory, Clinical), direct management of IMP supply requirements and logistics, MS-Project Plans (Gantt charts) Show less

      • Principal Scientist, Medicinal Chemistry / Project Manager

        Aug 2014 - Dec 2017
      • Senior Scientist, Medicinal Chemistry

        Oct 2007 - Aug 2014
    • Immunocore

      Dec 2017 - Feb 2020

      -Continued integration of Project Management (MSP plans) within CMC across multiple Development programs of ImmTAXs (MSP Plans, Progress Monitoring, Risk Register, Actions)-Individual CMC Project leadership in cross-functional teams in Oncology-Key point of contact and management of external CMO/CROs-Facilitate effective PTMs: minutes, actions, team decisions, risk log-Close interaction with CMC and regulatory group (pre-IND, IND, IMPD, etc..)-Foster communication between Development, Clinical Supplies, Finance and Quality Show less

      • Senior Project Manager, CMC

        Jan 2019 - Feb 2020
      • Project Manager, CMC

        Dec 2017 - Dec 2018
    • ADC Therapeutics

      Feb 2020 - Oct 2023

      -Project management Lead of preclinical and clinical stage development programs-Manage and oversee work of internal/external cross-functional Project team members to effectively hit deliverables/milestones (Preclinical, CMC, Clinical, Regulatory, Finance, Alliance/Marketing)-Analyse and critically review project status/timelines/budgets within long-term goals-Develop tools and mechanisms for Project monitoring (plans, logs, dashboards, reports)

      • Project Director, Global Project Management

        Mar 2023 - Oct 2023
      • Project Leader, Global Project Management

        Feb 2020 - Mar 2023
    • Avacta

      Oct 2023 - Mar 2024
      VP, Global Project Management
    • Myricx Bio

      Jun 2024 - now
      Director, Project Management
  • Licenses & Certifications

    • Project Management Professional (PMP)

      Project Management Institute
      Nov 2021
    • GCP Foundation Course

      Institute of Clinical Research
      Mar 2017
    • Prince2 Foundation & Practitioner

      BCS, The Chartered Institute for IT
      Nov 2016